Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   LPB220_RS10355 Genome accession   NZ_CP044230
Coordinates   2051001..2052269 (-) Length   422 a.a.
NCBI ID   WP_150906731.1    Uniprot ID   A0A5J6LR66
Organism   Streptococcus sp. LPB0220     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2046001..2057269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB220_RS10325 (LPB220_10330) - 2047378..2047683 (-) 306 WP_003001941.1 DUF1292 domain-containing protein -
  LPB220_RS10330 (LPB220_10335) ruvX 2047706..2048125 (-) 420 WP_023919889.1 Holliday junction resolvase RuvX -
  LPB220_RS10335 (LPB220_10340) - 2048125..2048391 (-) 267 WP_003002070.1 IreB family regulatory phosphoprotein -
  LPB220_RS10340 (LPB220_10345) - 2048516..2049112 (-) 597 WP_150906727.1 SP0191 family lipoprotein -
  LPB220_RS10345 (LPB220_10350) spx 2049249..2049647 (-) 399 WP_150906729.1 transcriptional regulator Spx -
  LPB220_RS10350 (LPB220_10355) recA 2049735..2050880 (-) 1146 WP_003002082.1 recombinase RecA Machinery gene
  LPB220_RS10355 (LPB220_10360) cinA 2051001..2052269 (-) 1269 WP_150906731.1 competence/damage-inducible protein A Machinery gene
  LPB220_RS10365 (LPB220_10370) - 2052801..2053838 (+) 1038 WP_150906733.1 S66 peptidase family protein -
  LPB220_RS10370 (LPB220_10375) - 2053891..2054457 (-) 567 WP_150906735.1 DNA-3-methyladenine glycosylase I -
  LPB220_RS10375 (LPB220_10380) ruvA 2054467..2055060 (-) 594 WP_150906737.1 Holliday junction branch migration protein RuvA -
  LPB220_RS10380 (LPB220_10385) mutL 2055081..2057024 (-) 1944 WP_070594641.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45139.30 Da        Isoelectric Point: 4.8024

>NTDB_id=389013 LPB220_RS10355 WP_150906731.1 2051001..2052269(-) (cinA) [Streptococcus sp. LPB0220]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGIDVYYHVAVGDNEGRLFSTIETASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGKELVFDPTALAKLDTFFASRPDYVRTPNNERQAQMIAGSIPLQNRTGLAVGGLIEVDDVTYVVLPGPPSELKPM
VNEQLVPHLTTGEQLFSRVLRFFGIGESQLVTILADIIEEQSDPTVAPYAKTGEVTLRLSTKAKDQASADAKLDVLEKEI
LSRHTLDHQPLHELFYGYGDDNSMAKVAFDLLKGTGKTITVAESLTAGLFQATLADFSGASSIFAGGFVTYSLEEKSKML
SIPAQELEQHGVVSHFTAQAMASQARKLTGSDYGVSLTGVAGPDSLEGHPAGTVFIGLATPHGVDSVQVNIAGRSRADVR
EIAVLHAFNLVRLAVLNGENLV

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=389013 LPB220_RS10355 WP_150906731.1 2051001..2052269(-) (cinA) [Streptococcus sp. LPB0220]
ATGAAGGCGGAAATTATTGCAGTTGGAACAGAAATTCTAACAGGACAAATTGTGAACACCAATGCTCAATTCTTGTCTGA
AAAATTGGCTAGTTTAGGGATTGATGTCTATTATCATGTGGCGGTAGGAGACAATGAAGGCCGTCTCTTCTCGACCATTG
AGACAGCTTCAAAACGCAGTGATTTGGTGATTTTATGCGGTGGACTTGGGCCAACAGAGGATGATTTGACCAAGCAAACC
CTTGCTAAGTTTTTAGGGAAAGAACTGGTTTTTGATCCGACAGCGCTTGCTAAACTCGACACCTTCTTTGCCAGTCGCCC
TGATTATGTCCGGACGCCCAATAATGAGCGACAAGCACAAATGATCGCCGGATCAATCCCCCTTCAAAACCGTACAGGTC
TCGCGGTTGGAGGTTTGATTGAAGTCGATGATGTGACCTATGTCGTTCTACCTGGTCCGCCAAGTGAGTTAAAACCCATG
GTCAATGAACAATTGGTGCCTCATTTGACAACAGGGGAACAGCTCTTTTCAAGAGTCTTGCGCTTCTTTGGGATTGGGGA
AAGCCAGCTGGTTACGATCCTAGCAGATATCATTGAAGAGCAGAGTGATCCGACGGTTGCCCCTTATGCCAAGACGGGAG
AAGTAACCTTGCGTCTATCTACAAAGGCGAAGGATCAAGCTTCAGCGGATGCTAAGCTCGATGTCTTAGAAAAGGAAATC
TTATCACGTCACACGCTGGACCATCAACCCTTGCATGAACTGTTTTACGGTTATGGGGATGACAATTCGATGGCCAAGGT
TGCCTTTGATCTCTTGAAAGGGACTGGTAAGACCATTACAGTTGCAGAAAGCCTGACGGCTGGCCTCTTTCAAGCGACTT
TGGCAGATTTTTCAGGGGCGTCCAGCATCTTCGCGGGTGGTTTTGTCACCTATAGTCTGGAAGAAAAAAGCAAGATGTTG
TCTATTCCAGCTCAAGAGTTGGAGCAACATGGAGTTGTGTCTCATTTTACAGCACAAGCCATGGCTTCACAGGCCCGTAA
GTTAACAGGATCCGATTATGGTGTTAGCCTAACCGGAGTTGCGGGGCCAGATAGTCTAGAAGGGCATCCAGCAGGGACCG
TCTTTATCGGACTTGCGACTCCACATGGAGTGGATAGTGTCCAAGTCAATATCGCTGGACGTAGCCGGGCGGATGTCCGC
GAAATTGCAGTCCTTCATGCCTTTAATTTGGTGCGCTTGGCTGTATTAAATGGTGAAAATTTGGTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-412)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5J6LR66

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.58

98.815

0.737
  cinA Streptococcus mitis NCTC 12261

74.341

98.815

0.735
  cinA Streptococcus pneumoniae TIGR4

73.141

98.815

0.723
  cinA Streptococcus pneumoniae Rx1

73.141

98.815

0.723
  cinA Streptococcus pneumoniae R6

73.141

98.815

0.723
  cinA Streptococcus pneumoniae D39

72.902

98.815

0.72
  cinA Streptococcus mutans UA159

70.213

100

0.704
  cinA Streptococcus suis isolate S10

55.448

97.867

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

46.618

98.104

0.457

Multiple sequence alignment