Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   LPB220_RS04060 Genome accession   NZ_CP044230
Coordinates   756808..757476 (+) Length   222 a.a.
NCBI ID   WP_150905697.1    Uniprot ID   A0A5J6LLL6
Organism   Streptococcus sp. LPB0220     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 751808..762476
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB220_RS04035 (LPB220_04035) - 752246..752509 (-) 264 WP_150905693.1 GIY-YIG nuclease family protein -
  LPB220_RS04040 (LPB220_04040) - 752499..753245 (-) 747 WP_021152863.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  LPB220_RS04050 (LPB220_04050) - 753480..755819 (-) 2340 WP_150905695.1 cation-translocating P-type ATPase -
  LPB220_RS04055 (LPB220_04055) - 755995..756741 (+) 747 WP_070673821.1 lysophospholipid acyltransferase family protein -
  LPB220_RS04060 (LPB220_04060) comEA/celA/cilE 756808..757476 (+) 669 WP_150905697.1 helix-hairpin-helix domain-containing protein Machinery gene
  LPB220_RS04065 (LPB220_04065) comEC/celB 757457..759703 (+) 2247 WP_150905699.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  LPB220_RS04070 (LPB220_04070) - 759779..760381 (+) 603 WP_150905701.1 DUF805 domain-containing protein -
  LPB220_RS04075 (LPB220_04075) holA 760405..761439 (+) 1035 WP_049486408.1 DNA polymerase III subunit delta -
  LPB220_RS04080 (LPB220_04080) sodA 761528..762133 (+) 606 WP_150905703.1 superoxide dismutase SodA -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 23857.65 Da        Isoelectric Point: 4.9978

>NTDB_id=388988 LPB220_RS04060 WP_150905697.1 756808..757476(+) (comEA/celA/cilE) [Streptococcus sp. LPB0220]
MEDIIEKIKEYKLFLALTAIGLLLGGYFLFHRPQSSASTIPDLYQASSSTSSKEKVQTTSSKEEKTATSVSDAPEIITVD
VKGAVKQPGVYELRSNSRVHDAIYKAGGMTADANSQSVNLAQKLSDEAVIYVAKEGEDVPELGSSESPATSSAPAEKTGK
VHLNRATESDLQTVSGIGQKRAQDIIAYREANGPFRSVDDLKNVSGIGEKTLEKLRDAFTVD

Nucleotide


Download         Length: 669 bp        

>NTDB_id=388988 LPB220_RS04060 WP_150905697.1 756808..757476(+) (comEA/celA/cilE) [Streptococcus sp. LPB0220]
ATGGAGGATATCATCGAAAAAATCAAAGAATATAAGCTATTTTTAGCTCTTACTGCTATCGGACTCTTACTTGGAGGGTA
TTTTCTTTTTCATCGACCTCAGTCAAGTGCATCCACCATACCGGATCTTTATCAGGCTTCTAGTTCAACTTCGAGCAAAG
AAAAGGTGCAGACCACTAGTTCCAAAGAAGAAAAGACGGCGACTTCTGTGTCTGATGCACCCGAGATCATTACGGTCGAT
GTCAAAGGAGCCGTCAAACAACCAGGTGTCTATGAGTTGCGCTCCAATAGCAGAGTCCACGATGCTATTTATAAGGCAGG
CGGGATGACAGCAGATGCCAATAGTCAATCGGTCAACTTGGCGCAAAAACTCTCCGATGAAGCAGTGATCTATGTTGCTA
AAGAAGGAGAGGATGTTCCAGAACTTGGAAGTTCAGAAAGTCCTGCAACTTCGTCAGCACCAGCAGAAAAAACAGGCAAG
GTCCATTTAAATCGAGCAACCGAATCAGATCTCCAGACAGTATCAGGCATTGGCCAGAAACGTGCCCAGGACATTATCGC
CTATCGCGAAGCAAATGGTCCTTTTCGATCAGTGGATGATCTGAAGAATGTTTCAGGAATCGGAGAGAAAACACTGGAGA
AACTAAGAGATGCTTTCACGGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(158-219)

SLBB domain (SLBB)

(79-132)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5J6LLL6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

49.778

100

0.505
  comEA/celA/cilE Streptococcus mitis SK321

49.554

100

0.5
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50

100

0.5
  comEA/celA/cilE Streptococcus pneumoniae R6

49.55

100

0.496
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.55

100

0.496
  comEA/celA/cilE Streptococcus pneumoniae D39

49.55

100

0.496
  comEA Lactococcus lactis subsp. cremoris KW2

42.241

100

0.441
  comEA Streptococcus thermophilus LMD-9

42.982

100

0.441
  comEA Staphylococcus aureus MW2

35.874

100

0.36

Multiple sequence alignment