Detailed information NTG0388989

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: LPB220_RS04065
• Genome accession: NZ_CP044230
• Coordinates: 757457..759703 (+)
• Length: 748 a.a.
• NCBI ID: WP_150905699.1
• Uniprot ID: A0A5J6LL16
• Organism: Streptococcus sp. LPB0220
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 752457..764703

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LPB220_RS04040 (LPB220_04040)	-	752499..753245 (-)	747	WP_021152863.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
LPB220_RS04050 (LPB220_04050)	-	753480..755819 (-)	2340	WP_150905695.1	cation-translocating P-type ATPase	-
LPB220_RS04055 (LPB220_04055)	-	755995..756741 (+)	747	WP_070673821.1	lysophospholipid acyltransferase family protein	-
LPB220_RS04060 (LPB220_04060)	comEA/celA/cilE	756808..757476 (+)	669	WP_150905697.1	helix-hairpin-helix domain-containing protein	Machinery gene
LPB220_RS04065 (LPB220_04065)	comEC/celB	757457..759703 (+)	2247	WP_150905699.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LPB220_RS04070 (LPB220_04070)	-	759779..760381 (+)	603	WP_150905701.1	DUF805 domain-containing protein	-
LPB220_RS04075 (LPB220_04075)	holA	760405..761439 (+)	1035	WP_049486408.1	DNA polymerase III subunit delta	-
LPB220_RS04080 (LPB220_04080)	sodA	761528..762133 (+)	606	WP_150905703.1	superoxide dismutase SodA	-
LPB220_RS04085 (LPB220_04085)	-	762344..763816 (+)	1473	WP_150905705.1	helicase HerA-like domain-containing protein	-

Sequence

Protein

• Length: 748 a.a.
• Molecular weight: 85714.18 Da
• Isoelectric Point: 9.3102

>NTDB_id=388989 LPB220_RS04065 WP_150905699.1 757457..759703(+) (comEC/celB) [Streptococcus sp. LPB0220]
MLSRWIKDLPFSLVHLAFVLLWLYFSIYQPSWLSISGLVVVGVLAVHHYKGERSSLLGLALANLCFAAFFVFQRLQDHPV
QAESQPPSHLRLIPDTIKINGDALSFRAKNQGRTYQVFYTLKSEKEKQQWQSQTRLMELTYKGVIEEPEGQRNFRGFDYR
SYLETQGIHYQIKIEAIQSAVPIQTWNVFDWLSQWRRQAIVWSKEHFPQPMNQYMTGLLFGYLDTDFEEMDQLYTSLGII
HLFALSGMQVGFFINGIRKALLRLGILQETVDIWMLPISLVYAGLTGFSVSVVRSLLQKILSQKGIRGMENMAMTLMILM
VLMPKFLLTAGGVLSCAYAFILTLVDTSSYSGLKKLLVESFWISLGILPLLTYYFSVFQPWSLPLTFLFSFLFDLVLLPG
LTVLFILSILKPLTIFNSFFLLIEECIRWISKLTSLPLVFGQPTGPALIALFLLLGILYDLRKQKKRRFLLIGMILLIFC
WTKHPLENEITMVDIGQGDSIFLRDWKGRTILIDVGGRVTFKSGEKWQERSQSANADQTLIPYLKSRGVGKLDALVLTHT
DQDHMGDMVEVAKQIPVKKVYVSPGSLTNSQFREKLKQLHSPIKVVQRGDQLPIFDHHLEVLSPDEVGDGKNDDSIVLYG
QFFQKRFLFTGDLEEAGEKKLLKNDPQLQVDVLKVGHHGSKGSSSDVFLDQLHPQLALISVGKKNRYQHPHKELLDRLEE
RSISYLRTDERGAIRLIGWDHWRVETVR

Nucleotide

• Length: 2247 bp

>NTDB_id=388989 LPB220_RS04065 WP_150905699.1 757457..759703(+) (comEC/celB) [Streptococcus sp. LPB0220]
ATGCTTTCACGGTGGATTAAAGACCTTCCTTTTTCGCTTGTCCATCTCGCCTTTGTGCTCCTATGGCTGTATTTTAGTAT
CTATCAACCATCTTGGCTTTCGATCAGCGGTCTAGTAGTAGTGGGAGTTTTAGCGGTTCATCACTATAAAGGGGAGCGCT
CAAGTTTGCTAGGGCTTGCTTTAGCAAACCTTTGTTTTGCGGCCTTCTTTGTCTTTCAGCGACTACAGGATCATCCAGTA
CAAGCAGAAAGTCAGCCCCCATCCCACTTACGCCTGATTCCAGATACCATCAAGATCAATGGGGACGCCCTGTCTTTTCG
TGCTAAAAATCAGGGAAGGACCTACCAAGTCTTCTACACTTTAAAATCAGAAAAAGAAAAACAGCAGTGGCAAAGTCAAA
CCCGCTTGATGGAGTTGACATATAAAGGTGTTATAGAAGAACCAGAAGGGCAACGAAATTTTAGAGGATTTGACTACCGG
TCTTATTTGGAAACACAGGGAATTCACTATCAAATAAAAATTGAAGCGATCCAATCTGCGGTTCCCATCCAAACGTGGAA
TGTTTTTGACTGGCTATCTCAATGGAGGCGCCAAGCCATTGTTTGGAGCAAGGAGCACTTTCCACAGCCGATGAACCAGT
ATATGACCGGCCTTCTTTTTGGTTATTTAGATACGGATTTTGAAGAGATGGATCAGCTTTACACGAGTTTGGGCATCATC
CATTTGTTCGCCTTATCTGGGATGCAGGTCGGCTTTTTCATCAATGGGATCCGGAAAGCTCTCTTACGTCTAGGAATCTT
GCAAGAGACAGTCGATATCTGGATGCTTCCAATTTCTTTGGTCTATGCTGGCTTGACAGGTTTTTCAGTTTCAGTGGTTC
GTAGTCTCTTGCAGAAGATCCTCTCTCAAAAGGGGATCCGAGGGATGGAGAATATGGCGATGACCTTGATGATCTTAATG
GTGCTCATGCCCAAGTTTCTTCTGACAGCTGGAGGGGTCTTGAGTTGTGCCTACGCCTTTATTTTGACCTTGGTAGATAC
CAGTTCTTATTCAGGACTTAAAAAGCTACTAGTGGAAAGTTTCTGGATTAGCCTGGGAATTTTGCCCCTTTTGACCTATT
ACTTTAGTGTCTTTCAACCGTGGTCACTCCCTTTAACCTTCCTCTTTTCTTTCTTATTTGACCTTGTCCTTCTTCCAGGT
TTAACGGTGCTATTTATCTTATCGATTCTAAAGCCCCTTACAATTTTTAACAGTTTCTTTCTTCTCATAGAGGAGTGTAT
TCGTTGGATTTCAAAGCTCACGTCGCTACCTTTGGTATTTGGTCAGCCGACGGGACCAGCTCTGATTGCTCTCTTCCTTC
TTTTAGGAATCTTGTATGATCTTCGAAAGCAAAAAAAACGTCGTTTCCTGTTAATAGGCATGATTCTACTCATCTTTTGT
TGGACCAAGCATCCTTTAGAAAATGAGATTACCATGGTGGATATTGGTCAAGGAGACAGTATCTTTTTACGCGATTGGAA
AGGAAGAACCATATTGATTGATGTCGGAGGACGTGTCACTTTTAAAAGTGGAGAAAAGTGGCAAGAGCGCAGTCAATCTG
CCAATGCGGATCAAACCTTGATTCCCTATCTCAAGAGTCGTGGTGTTGGAAAACTCGATGCTTTGGTCTTGACTCATACA
GACCAGGACCATATGGGCGATATGGTGGAGGTTGCCAAACAAATCCCAGTTAAAAAAGTGTATGTCAGTCCAGGTAGTCT
AACTAATTCTCAATTTCGAGAGAAATTGAAACAGCTTCATAGTCCGATTAAAGTAGTCCAGAGAGGAGATCAACTACCTA
TTTTTGATCATCATCTAGAAGTCTTATCCCCTGATGAAGTGGGGGATGGTAAAAATGATGATTCAATTGTCCTCTATGGG
CAGTTCTTTCAGAAACGATTTTTGTTCACGGGTGATTTGGAAGAAGCTGGAGAGAAAAAACTATTGAAAAACGATCCACA
ATTACAAGTAGATGTCTTGAAAGTAGGCCACCACGGTTCTAAAGGTTCCTCTAGTGATGTGTTTTTAGATCAGTTACATC
CTCAGTTGGCCTTGATCTCTGTTGGAAAGAAAAATCGCTACCAACATCCCCATAAAGAATTGCTCGATCGTCTAGAGGAA
CGCTCTATTTCTTACCTTCGTACCGATGAAAGGGGAGCGATTCGCTTGATTGGGTGGGACCATTGGAGGGTAGAAACGGT
CCGCTAG

Domains

Predicted by InterproScan.

• Competence protein (Competence) (218-463)

• Metallo-beta-lactamase superfamily (Lactamase_B) (496-700)

• Domain of unknown function (DUF4131) (DUF4131) (30-178)

3D structure

• AlphaFold DB: A0A5J6LL16

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	53.805	100	0.539
comEC/celB	Streptococcus mitis NCTC 12261	52.815	99.733	0.527
comEC/celB	Streptococcus pneumoniae TIGR4	52.61	99.866	0.525
comEC/celB	Streptococcus pneumoniae Rx1	52.343	99.866	0.523
comEC/celB	Streptococcus pneumoniae D39	52.343	99.866	0.523
comEC/celB	Streptococcus pneumoniae R6	52.343	99.866	0.523
comEC	Lactococcus lactis subsp. cremoris KW2	46.996	100	0.471