Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYD   Type   Machinery gene
Locus tag   LPB220_RS01230 Genome accession   NZ_CP044230
Coordinates   212011..212415 (+) Length   134 a.a.
NCBI ID   WP_003004513.1    Uniprot ID   A0A414PH54
Organism   Streptococcus sp. LPB0220     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 207011..217415
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB220_RS01210 (LPB220_01210) - 209325..209714 (+) 390 WP_042759849.1 DUF1033 family protein -
  LPB220_RS01215 (LPB220_01215) comYA 209802..210743 (+) 942 WP_021154281.1 competence type IV pilus ATPase ComGA Machinery gene
  LPB220_RS01220 (LPB220_01220) comYB 210676..211707 (+) 1032 WP_176745544.1 competence type IV pilus assembly protein ComGB Machinery gene
  LPB220_RS01225 (LPB220_01225) comYC 211704..212021 (+) 318 WP_150905144.1 competence type IV pilus major pilin ComGC Machinery gene
  LPB220_RS01230 (LPB220_01230) comYD 212011..212415 (+) 405 WP_003004513.1 competence type IV pilus minor pilin ComGD Machinery gene
  LPB220_RS01235 (LPB220_01235) comGE 212381..212668 (+) 288 WP_003004353.1 competence type IV pilus minor pilin ComGE -
  LPB220_RS01240 (LPB220_01240) comGF/cglF 212658..213110 (+) 453 WP_031572613.1 competence type IV pilus minor pilin ComGF Machinery gene
  LPB220_RS01245 (LPB220_01245) comGG 213067..213534 (+) 468 WP_225305918.1 competence type IV pilus minor pilin ComGG -
  LPB220_RS01250 (LPB220_01250) comYH 213565..214518 (+) 954 WP_021154287.1 class I SAM-dependent methyltransferase Machinery gene
  LPB220_RS01255 (LPB220_01255) - 214570..215763 (+) 1194 WP_150905146.1 acetate kinase -
  LPB220_RS01260 (LPB220_01260) - 215836..216567 (+) 732 WP_150905148.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 134 a.a.        Molecular weight: 15164.50 Da        Isoelectric Point: 9.7563

>NTDB_id=388961 LPB220_RS01230 WP_003004513.1 212011..212415(+) (comYD) [Streptococcus sp. LPB0220]
MQIKAFTLVETLLTLMIVSFIYLGLSGSIKTSFQQVEEKVFFAEFEHLYQESQKIALARQTELDVEVTARKIQTPYQTVE
IPDSVILQDPKTIRLDRAGGNSSLANVHFQTQRGVVTYQLSLGNGKIKKSIRSR

Nucleotide


Download         Length: 405 bp        

>NTDB_id=388961 LPB220_RS01230 WP_003004513.1 212011..212415(+) (comYD) [Streptococcus sp. LPB0220]
TTGCAGATTAAGGCCTTCACCTTGGTGGAGACCCTTCTGACCTTGATGATCGTCAGTTTTATCTATCTGGGCTTATCGGG
ATCGATCAAGACGAGCTTTCAGCAGGTGGAAGAAAAAGTATTTTTTGCAGAGTTTGAACACCTCTATCAAGAAAGCCAGA
AAATAGCGCTGGCAAGGCAAACGGAATTGGATGTTGAAGTGACTGCAAGGAAGATTCAAACGCCTTACCAGACGGTGGAG
ATTCCTGATTCTGTCATTTTGCAAGATCCTAAAACTATTCGTTTAGACCGAGCAGGTGGCAATTCATCCCTGGCCAATGT
TCACTTTCAGACACAGAGAGGAGTGGTGACCTATCAACTGTCGCTTGGAAATGGGAAAATTAAAAAAAGCATCCGTTCCC
GCTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A414PH54

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYD Streptococcus gordonii str. Challis substr. CH1

50

97.015

0.485
  comGD/cglD Streptococcus mitis NCTC 12261

48.837

96.269

0.47
  comGD/cglD Streptococcus pneumoniae Rx1

48.819

94.776

0.463
  comGD/cglD Streptococcus pneumoniae D39

48.819

94.776

0.463
  comGD/cglD Streptococcus pneumoniae R6

48.819

94.776

0.463
  comGD/cglD Streptococcus mitis SK321

48.819

94.776

0.463
  comGD/cglD Streptococcus pneumoniae TIGR4

48.031

94.776

0.455
  comYD Streptococcus mutans UA140

44.615

97.015

0.433
  comYD Streptococcus mutans UA159

44.615

97.015

0.433

Multiple sequence alignment