Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   LPB220_RS01220 Genome accession   NZ_CP044230
Coordinates   210676..211707 (+) Length   343 a.a.
NCBI ID   WP_176745544.1    Uniprot ID   -
Organism   Streptococcus sp. LPB0220     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 205676..216707
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LPB220_RS01210 (LPB220_01210) - 209325..209714 (+) 390 WP_042759849.1 DUF1033 family protein -
  LPB220_RS01215 (LPB220_01215) comYA 209802..210743 (+) 942 WP_021154281.1 competence type IV pilus ATPase ComGA Machinery gene
  LPB220_RS01220 (LPB220_01220) comYB 210676..211707 (+) 1032 WP_176745544.1 competence type IV pilus assembly protein ComGB Machinery gene
  LPB220_RS01225 (LPB220_01225) comYC 211704..212021 (+) 318 WP_150905144.1 competence type IV pilus major pilin ComGC Machinery gene
  LPB220_RS01230 (LPB220_01230) comYD 212011..212415 (+) 405 WP_003004513.1 competence type IV pilus minor pilin ComGD Machinery gene
  LPB220_RS01235 (LPB220_01235) comGE 212381..212668 (+) 288 WP_003004353.1 competence type IV pilus minor pilin ComGE -
  LPB220_RS01240 (LPB220_01240) comGF/cglF 212658..213110 (+) 453 WP_031572613.1 competence type IV pilus minor pilin ComGF Machinery gene
  LPB220_RS01245 (LPB220_01245) comGG 213067..213534 (+) 468 WP_225305918.1 competence type IV pilus minor pilin ComGG -
  LPB220_RS01250 (LPB220_01250) comYH 213565..214518 (+) 954 WP_021154287.1 class I SAM-dependent methyltransferase Machinery gene
  LPB220_RS01255 (LPB220_01255) - 214570..215763 (+) 1194 WP_150905146.1 acetate kinase -
  LPB220_RS01260 (LPB220_01260) - 215836..216567 (+) 732 WP_150905148.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39349.32 Da        Isoelectric Point: 9.9155

>NTDB_id=388959 LPB220_RS01220 WP_176745544.1 210676..211707(+) (comYB) [Streptococcus sp. LPB0220]
MSWLNRDISSWLRRKPKKLSTAKQKQIIELFLNLYSSGFHLSEIVDFLDRSHLVESRLVSQMREDLSRGRSFSEMMAGIG
FSDAVTTQLSLAELHGNLALSLEKISAYLENMRKVKKKLIEVSTYPLILLGFLVLIMLGLRNYLLPQMDAQNIGTQLISS
FPQLFLALGAGLVIFFLLSFLYYRKSGKIKVFRTLSHLPFGKGMIQAYLTAYYAREWGNLIGQGLELSQIFSMMQGQKSQ
LFQEIGRDLALSLDRGQSFSETVRGYSFFKKELSLMIEYGEVKSKLGSELEIYAEKTWEDFFRRVHKAMNVIQPLVFVFV
ALVIVLLYAAMLLPIYQNMEVHL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=388959 LPB220_RS01220 WP_176745544.1 210676..211707(+) (comYB) [Streptococcus sp. LPB0220]
ATCTCTTGGCTCAATCGGGATATATCCAGCTGGCTCAGGCGCAAGCCGAAAAAATTATCTACCGCTAAACAAAAGCAAAT
CATCGAATTGTTTTTGAATCTTTATTCGAGTGGTTTTCATCTGTCTGAGATTGTCGATTTTCTGGATCGCTCTCACCTAG
TGGAGAGTCGTTTGGTTTCCCAGATGCGAGAGGACCTCTCGAGGGGGCGGAGTTTTTCAGAGATGATGGCGGGGATCGGT
TTTTCAGATGCGGTCACGACACAGCTGTCTCTCGCTGAACTCCATGGCAATCTTGCATTGAGCTTGGAGAAAATCAGTGC
TTACCTAGAAAACATGCGCAAGGTCAAGAAAAAGCTGATTGAGGTGAGCACCTATCCTCTCATCTTGCTTGGATTTTTAG
TTCTGATTATGCTAGGCCTGCGCAATTACTTGCTTCCTCAAATGGATGCTCAAAATATTGGGACGCAATTGATCAGTTCC
TTCCCCCAACTCTTTTTGGCCTTAGGAGCGGGACTGGTGATCTTCTTCTTACTCAGCTTTCTCTATTATCGAAAGTCAGG
CAAGATCAAGGTTTTTAGAACCTTGTCTCATCTGCCTTTCGGGAAAGGCATGATTCAAGCTTATTTGACAGCCTATTATG
CCAGAGAATGGGGTAATCTGATTGGACAAGGATTGGAATTGTCTCAGATTTTTTCCATGATGCAGGGGCAAAAATCCCAG
CTTTTTCAGGAAATTGGAAGGGACTTAGCTCTTTCTTTAGATCGTGGCCAGTCCTTTTCAGAGACGGTCAGGGGGTATTC
TTTTTTCAAAAAAGAATTGTCCCTTATGATTGAATACGGTGAAGTCAAATCAAAGCTCGGAAGTGAGCTAGAGATCTACG
CTGAAAAAACATGGGAAGATTTCTTTCGTCGGGTTCACAAGGCCATGAATGTGATACAACCCTTGGTGTTTGTCTTTGTG
GCTCTTGTGATTGTCTTACTCTATGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGGTTCATTTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)

Type II secretion system (T2SS), protein F (T2SSF)

(28-146)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

65.598

100

0.656
  comGB/cglB Streptococcus mitis SK321

66.369

97.959

0.65
  comGB/cglB Streptococcus mitis NCTC 12261

65.774

97.959

0.644
  comGB/cglB Streptococcus pneumoniae TIGR4

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae R6

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae Rx1

65.476

97.959

0.641
  comGB/cglB Streptococcus pneumoniae D39

65.476

97.959

0.641
  comYB Streptococcus mutans UA159

58.43

100

0.586
  comYB Streptococcus mutans UA140

58.43

100

0.586
  comGB Lactococcus lactis subsp. cremoris KW2

49.555

98.251

0.487

Multiple sequence alignment