Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   F5989_RS07445 Genome accession   NZ_CP044221
Coordinates   1502835..1503149 (+) Length   104 a.a.
NCBI ID   WP_002263437.1    Uniprot ID   -
Organism   Streptococcus mutans strain NCH105     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context


Location: 1497835..1508149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F5989_RS07430 (F5989_07565) - 1500414..1500797 (+) 384 WP_002264248.1 DUF1033 family protein -
  F5989_RS07435 (F5989_07570) comYA 1500927..1501868 (+) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  F5989_RS07440 (F5989_07575) comYB 1501804..1502835 (+) 1032 WP_255262721.1 competence type IV pilus assembly protein ComGB Machinery gene
  F5989_RS07445 (F5989_07580) comYC 1502835..1503149 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  F5989_RS07450 (F5989_07585) comYD 1503136..1503540 (+) 405 WP_002264246.1 competence type IV pilus minor pilin ComGD Machinery gene
  F5989_RS07455 (F5989_07590) comYE 1503512..1503805 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  F5989_RS07460 (F5989_07595) comYF 1503792..1504226 (+) 435 WP_061046398.1 competence type IV pilus minor pilin ComGF Machinery gene
  F5989_RS07465 (F5989_07600) comYG 1504204..1504593 (+) 390 WP_002263441.1 competence type IV pilus minor pilin ComGG Machinery gene
  F5989_RS07470 (F5989_07605) comYH 1504648..1505601 (+) 954 WP_002263442.1 class I SAM-dependent methyltransferase Machinery gene
  F5989_RS07475 (F5989_07610) - 1505660..1506859 (+) 1200 WP_002263443.1 acetate kinase -
  F5989_RS07480 (F5989_07615) - 1507412..1507657 (+) 246 WP_002263444.1 helix-turn-helix transcriptional regulator -
  F5989_RS07485 (F5989_07620) - 1507626..1508066 (+) 441 WP_002263445.1 hypothetical protein -

Sequence


Protein


Download         Length: 104 a.a.        Molecular weight: 11591.60 Da        Isoelectric Point: 10.2206

>NTDB_id=388855 F5989_RS07445 WP_002263437.1 1502835..1503149(+) (comYC) [Streptococcus mutans strain NCH105]
MKKIKRVSVRAFTLIEMLVVLLIISILLLLFVPNLTKQKDKVKDTGGSAVVKVVESQAELYELNKTDSATLSKLVASGDI
TQEQANSYKDYYAKHPSKTRHVAN

Nucleotide


Download         Length: 315 bp        

>NTDB_id=388855 F5989_RS07445 WP_002263437.1 1502835..1503149(+) (comYC) [Streptococcus mutans strain NCH105]
ATGAAAAAGATCAAGAGAGTCAGTGTACGAGCTTTTACGCTTATAGAAATGTTAGTAGTTCTTCTCATTATTAGTATTCT
TTTACTATTATTTGTTCCTAATTTAACTAAGCAAAAAGATAAGGTAAAAGATACTGGCGGTTCTGCCGTGGTTAAAGTTG
TAGAAAGTCAGGCTGAGCTTTATGAGCTTAATAAAACCGATTCTGCTACTCTTTCTAAATTAGTAGCTAGTGGTGATATT
ACACAAGAACAGGCAAATTCATACAAGGATTACTATGCAAAACACCCAAGTAAAACACGGCATGTCGCGAATTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus mutans UA140

100

100

1

  comYC Streptococcus mutans UA159

100

100

1

  comYC Streptococcus gordonii str. Challis substr. CH1

71.429

100

0.721

  comGC/cglC Streptococcus mitis SK321

66.667

95.192

0.635

  comGC/cglC Streptococcus mitis NCTC 12261

69.565

88.462

0.615

  comGC/cglC Streptococcus pneumoniae R6

63.636

95.192

0.606

  comGC/cglC Streptococcus pneumoniae Rx1

63.636

95.192

0.606

  comGC/cglC Streptococcus pneumoniae D39

63.636

95.192

0.606

  comGC/cglC Streptococcus pneumoniae TIGR4

63.636

95.192

0.606

  comGC Lactococcus lactis subsp. cremoris KW2

55.446

97.115

0.538

  comYC Streptococcus suis isolate S10

60.227

84.615

0.51


Multiple sequence alignment