Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   FGL73_RS06390 Genome accession   NZ_CP042408
Coordinates   1358595..1359296 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain CBA3619     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1353595..1364296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL73_RS06370 (FGL73_06370) - 1353704..1354921 (-) 1218 WP_146978217.1 cysteine desulfurase -
  FGL73_RS06375 (FGL73_06375) sufD 1354921..1356177 (-) 1257 WP_038601850.1 Fe-S cluster assembly protein SufD -
  FGL73_RS06380 (FGL73_06380) sufC 1356315..1357085 (-) 771 WP_146978218.1 Fe-S cluster assembly ATPase SufC -
  FGL73_RS06385 (FGL73_06385) - 1357261..1358592 (-) 1332 WP_058205200.1 glycosyltransferase family 4 protein -
  FGL73_RS06390 (FGL73_06390) mecA 1358595..1359296 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  FGL73_RS06395 (FGL73_06395) - 1359426..1360160 (-) 735 WP_038601859.1 amino acid ABC transporter ATP-binding protein -
  FGL73_RS06400 (FGL73_06400) - 1360160..1360846 (-) 687 WP_098393284.1 amino acid ABC transporter permease -
  FGL73_RS06405 (FGL73_06405) - 1360994..1361902 (-) 909 WP_038601862.1 diacylglycerol kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=377709 FGL73_RS06390 WP_004255173.1 1358595..1359296(-) (mecA) [Lactococcus lactis strain CBA3619]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=377709 FGL73_RS06390 WP_004255173.1 1358595..1359296(-) (mecA) [Lactococcus lactis strain CBA3619]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGACATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTTGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATTGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97

Multiple sequence alignment