Detailed information NTG0377708

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: FGL73_RS06270
• Genome accession: NZ_CP042408
• Coordinates: 1337725..1338372 (-)
• Length: 215 a.a.
• NCBI ID: WP_146978211.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain CBA3619
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1332725..1343372

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL73_RS06245 (FGL73_06245)	atpF	1332795..1333301 (-)	507	WP_146978208.1	F0F1 ATP synthase subunit B	-
FGL73_RS06250 (FGL73_06250)	atpB	1333316..1334029 (-)	714	WP_146978209.1	F0F1 ATP synthase subunit A	-
FGL73_RS06255 (FGL73_06255)	-	1334074..1334289 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
FGL73_RS06260 (FGL73_06260)	-	1334473..1335249 (-)	777	WP_058206315.1	alpha/beta hydrolase family protein	-
FGL73_RS06265 (FGL73_06265)	comEC	1335534..1337744 (-)	2211	WP_146978210.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FGL73_RS06270 (FGL73_06270)	comEA	1337725..1338372 (-)	648	WP_146978211.1	ComEA family DNA-binding protein	Machinery gene
FGL73_RS06275 (FGL73_06275)	-	1338432..1339793 (-)	1362	WP_146978212.1	ABC transporter permease	-
FGL73_RS06280 (FGL73_06280)	-	1339790..1340722 (-)	933	WP_038601819.1	ABC transporter ATP-binding protein	-
FGL73_RS06285 (FGL73_06285)	-	1340826..1341224 (-)	399	WP_146978213.1	hypothetical protein	-
FGL73_RS06290 (FGL73_06290)	-	1341328..1341891 (-)	564	WP_098393297.1	GNAT family N-acetyltransferase	-
FGL73_RS06295 (FGL73_06295)	-	1342064..1343242 (-)	1179	WP_038601825.1	SLC13 family permease	-

Sequence

Protein

• Length: 215 a.a.
• Molecular weight: 23618.89 Da
• Isoelectric Point: 4.9882

>NTDB_id=377708 FGL73_RS06270 WP_146978211.1 1337725..1338372(-) (comEA) [Lactococcus lactis strain CBA3619]
MDKILEKVKEYWKMIVLVVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVIKFSEPNEKSVSKIMVDLKGAVTKP
NVYQISSDERLIDLIKEAGGFTDQADQKSINLSAKLKDEEVIYVPKIGENSSTENTDSSANSVISQVSTTTAKININQAD
LTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTLEKLKDELCFE

Nucleotide

• Length: 648 bp

>NTDB_id=377708 FGL73_RS06270 WP_146978211.1 1337725..1338372(-) (comEA) [Lactococcus lactis strain CBA3619]
ATGGATAAGATTTTAGAAAAAGTAAAAGAATACTGGAAAATGATTGTTTTAGTTGTTTGTGGGCTTATTGCTGGTGGGAT
TTTTTACGTTTTAACCAATGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT
CTGTCATTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAAGGTGCGGTAACAAAACCT
AATGTCTATCAAATTTCGTCAGATGAACGTCTAATTGATTTAATTAAAGAAGCTGGTGGTTTTACTGACCAAGCTGACCA
GAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTGGTGAAAATTCAAGCACAG
AAAATACTGACAGCTCTGCTAATTCGGTCATTAGTCAAGTCTCAACAACCACTGCAAAAATAAATATCAATCAAGCAGAT
TTAACAGAATTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATCGATTTTCGAACGAAAAATGGTGA
TTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTAGAAAAATTGAAAGATGAGTTATGTT
TTGAATAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (70-125)

• Helix-hairpin-helix motif (HHH_3) (152-212)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Lactococcus lactis subsp. cremoris KW2	75.229	100	0.763
comEA/celA/cilE	Streptococcus mitis SK321	44.444	100	0.447
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.119	100	0.437
comEA/celA/cilE	Streptococcus pneumoniae Rx1	42.202	100	0.428
comEA/celA/cilE	Streptococcus pneumoniae D39	42.202	100	0.428
comEA/celA/cilE	Streptococcus pneumoniae R6	42.202	100	0.428
comEA/celA/cilE	Streptococcus mitis NCTC 12261	41.284	100	0.419
comEA	Latilactobacillus sakei subsp. sakei 23K	36.123	100	0.381