Detailed information NTG0377707

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: FGL73_RS06265
• Genome accession: NZ_CP042408
• Coordinates: 1335534..1337744 (-)
• Length: 736 a.a.
• NCBI ID: WP_146978210.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain CBA3619
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1330534..1342744

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL73_RS06235 (FGL73_06235)	atpA	1330577..1332079 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
FGL73_RS06240 (FGL73_06240)	-	1332266..1332793 (-)	528	WP_029344288.1	F0F1 ATP synthase subunit delta	-
FGL73_RS06245 (FGL73_06245)	atpF	1332795..1333301 (-)	507	WP_146978208.1	F0F1 ATP synthase subunit B	-
FGL73_RS06250 (FGL73_06250)	atpB	1333316..1334029 (-)	714	WP_146978209.1	F0F1 ATP synthase subunit A	-
FGL73_RS06255 (FGL73_06255)	-	1334074..1334289 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
FGL73_RS06260 (FGL73_06260)	-	1334473..1335249 (-)	777	WP_058206315.1	alpha/beta hydrolase family protein	-
FGL73_RS06265 (FGL73_06265)	comEC	1335534..1337744 (-)	2211	WP_146978210.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
FGL73_RS06270 (FGL73_06270)	comEA	1337725..1338372 (-)	648	WP_146978211.1	ComEA family DNA-binding protein	Machinery gene
FGL73_RS06275 (FGL73_06275)	-	1338432..1339793 (-)	1362	WP_146978212.1	ABC transporter permease	-
FGL73_RS06280 (FGL73_06280)	-	1339790..1340722 (-)	933	WP_038601819.1	ABC transporter ATP-binding protein	-
FGL73_RS06285 (FGL73_06285)	-	1340826..1341224 (-)	399	WP_146978213.1	hypothetical protein	-
FGL73_RS06290 (FGL73_06290)	-	1341328..1341891 (-)	564	WP_098393297.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84561.37 Da
• Isoelectric Point: 9.7095

>NTDB_id=377707 FGL73_RS06265 WP_146978210.1 1335534..1337744(-) (comEC) [Lactococcus lactis strain CBA3619]
MSYVLNKIPLIFLAYLSVILYFLIFNFNLLCLILFIFSSLLALYRKYYLVIPLLLVMGSFFLVVKMDTIKNSENQPTTLS
KITMIPDTIQVNGDLLSFLGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLESQNI
YRQIMIDKTNKIVLNDTFDLHVLRRKAIVWSQTNFPKPMNDYMTGLLFGFLSKDFNQMGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRQNPLDNLAVTTLLLMIVSPKFLLTTGGQLT
LFYAFVISMISHKFSELKGIRKLLTESLVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYS
FNINLIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPIYPSITAV
DIGQGDSIFLQDKFNKETILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVQKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGKENRYGHPNQETLETLKKYQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=377707 FGL73_RS06265 WP_146978210.1 1335534..1337744(-) (comEC) [Lactococcus lactis strain CBA3619]
ATGAGTTATGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATATTGTATTTTTTAATTTTTAATTT
TAATTTACTTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCACTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAACAGTGAAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACGATCCAAGTTAATGGTGATTTATTAAGTTTTCTAGGAAAAGAAAGAGGACAAAATTA
TCAAGTTTACGAGACTCTAAAAAGCAAAAAAGAACAGAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAACCAAAAGTATTTAGAGAGCCAGAATATT
TATCGGCAAATTATGATTGATAAAACTAATAAAATAGTTTTAAATGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTAATTTTCCAAAGCCAATGAATGACTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATGGGAGACATTTATAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATCTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCAAAATCCTT
TAGATAATCTAGCGGTGACAACCCTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTCACT
TTATTTTATGCTTTTGTTATTTCAATGATTAGTCATAAATTTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATTAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATTTTTCAACCTTTTTCAATTTTACTGACGA
TTGGCTTTGGATTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAGT
TTTAATATAAATCTTATTTTTCAAATTCTTGAATGGCTAATTCATGAGGTTGATTTACCCTTGCATTATCCTTTGGTTTT
AGGGAATCCCAGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTTTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAATTTACCCCAGTATCACAGCAGTT
GATATTGGTCAAGGGGATAGTATTTTTTTGCAAGATAAATTTAATAAAGAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAATTGACAAATAATCATTTTGTACAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGCAAGGAAAATCGAT
ATGGACATCCCAACCAAGAAACTCTAGAAACATTAAAAAAATACCAAATCAGAATACTTAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-170)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

• Competence protein (Competence) (206-446)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.766	100	0.768
comEC/celB	Streptococcus mitis SK321	45.148	100	0.455
comEC/celB	Streptococcus mitis NCTC 12261	44.879	100	0.452
comEC/celB	Streptococcus pneumoniae TIGR4	44.28	100	0.447
comEC/celB	Streptococcus pneumoniae Rx1	43.876	100	0.443
comEC/celB	Streptococcus pneumoniae D39	43.876	100	0.443
comEC/celB	Streptococcus pneumoniae R6	43.876	100	0.443