Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   FNC98_RS02745 Genome accession   NZ_CP041638
Coordinates   628643..629890 (-) Length   415 a.a.
NCBI ID   WP_143579825.1    Uniprot ID   A0A516H9F6
Organism   Thalassotalea sp. PS06     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 623643..634890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNC98_RS02725 (FNC98_02725) - 625163..625990 (-) 828 WP_143579821.1 glycerophosphodiester phosphodiesterase family protein -
  FNC98_RS02730 (FNC98_02730) - 626012..626758 (-) 747 WP_143579822.1 cell division protein ZapD -
  FNC98_RS02735 (FNC98_02735) coaE 627011..627619 (-) 609 WP_143579823.1 dephospho-CoA kinase -
  FNC98_RS02740 (FNC98_02740) pilD 627672..628571 (-) 900 WP_313904112.1 A24 family peptidase Machinery gene
  FNC98_RS02745 (FNC98_02745) pilC 628643..629890 (-) 1248 WP_143579825.1 type II secretion system F family protein Machinery gene
  FNC98_RS02750 (FNC98_02750) pilB 629966..631663 (-) 1698 WP_143579826.1 type IV-A pilus assembly ATPase PilB Machinery gene
  FNC98_RS02755 (FNC98_02755) - 631759..632181 (-) 423 WP_313904113.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  FNC98_RS02760 (FNC98_02760) nadC 632701..633567 (-) 867 WP_143579828.1 carboxylating nicotinate-nucleotide diphosphorylase -
  FNC98_RS02765 (FNC98_02765) - 633606..634133 (-) 528 WP_143579829.1 TIGR02281 family clan AA aspartic protease -

Sequence

Protein


Download         Length: 415 a.a.        Molecular weight: 44780.05 Da        Isoelectric Point: 9.5583

>NTDB_id=372674 FNC98_RS02745 WP_143579825.1 628643..629890(-) (pilC) [Thalassotalea sp. PS06]
MAVTAAKKAPKVKELETFIWEGVNRKGKKIKGELSASNIGELKAQLRAQGVTPLKHKKKPKPLFGMGGGNKKIVPKDIAI
MTRQIATMLGAGVPLVQSIEMIGKGSEKPAMQQLLGEIGARVQAGIPLSDALREHPKYFDGLYCDLVQSGEQSGALETIY
DRIALYKEKAEALKSKIKKAMTYPIAVIVVAAIVTSILLIKVVPTFVDIFASFDAELPAFTRFVVSISDMMVASWYFVLA
GLFIAGYLFKQAHLKSQDFRDKVDKAVLKIPVIGMILDKAAVARFSRTLSTTFAAGVPLIDALESAAGASGNAVYRDAIR
EIRTEVAAGMQMNLAMRNVNVFPDMVIQMVSIGEESGALDDMLAKVATVYEQEVDDAVDGLTALLEPMIMAVLGVVIGGL
IIAMYLPIFQIGMVV

Nucleotide


Download         Length: 1248 bp        

>NTDB_id=372674 FNC98_RS02745 WP_143579825.1 628643..629890(-) (pilC) [Thalassotalea sp. PS06]
ATGGCAGTGACTGCAGCAAAAAAAGCGCCAAAAGTAAAAGAGCTGGAGACCTTCATTTGGGAAGGGGTAAACCGCAAAGG
CAAGAAAATTAAAGGGGAGCTGTCGGCTTCCAATATCGGTGAGTTAAAGGCCCAACTGCGAGCACAGGGTGTCACCCCTT
TAAAGCATAAGAAGAAGCCAAAACCGTTATTTGGCATGGGGGGTGGTAATAAAAAAATTGTCCCCAAAGATATCGCCATT
ATGACCCGACAAATAGCGACGATGTTGGGTGCCGGTGTGCCTTTAGTGCAATCCATTGAGATGATTGGTAAAGGCTCCGA
AAAACCTGCTATGCAGCAGCTACTGGGAGAAATAGGTGCTCGTGTACAGGCCGGTATCCCGCTCTCCGATGCGTTGCGTG
AGCATCCAAAATATTTTGATGGTCTCTACTGTGATTTAGTACAATCTGGTGAGCAATCCGGTGCTCTGGAAACTATCTAC
GATAGAATCGCTCTTTATAAAGAAAAAGCCGAAGCCCTTAAATCAAAAATTAAAAAGGCAATGACCTATCCGATTGCGGT
TATCGTGGTAGCAGCAATCGTGACCTCTATCTTGTTAATAAAAGTTGTTCCGACCTTTGTTGATATTTTTGCAAGCTTTG
ACGCGGAGCTGCCAGCATTTACTCGTTTCGTAGTGAGTATTTCCGATATGATGGTGGCCTCCTGGTACTTTGTGTTGGCA
GGCTTATTCATCGCTGGCTACCTGTTTAAGCAAGCGCACTTAAAGAGTCAGGATTTTCGCGATAAGGTTGATAAAGCAGT
ACTGAAAATACCGGTAATCGGGATGATCTTAGATAAAGCCGCTGTTGCCCGATTTTCCCGTACTCTATCGACGACCTTTG
CCGCCGGTGTGCCATTAATTGACGCCTTGGAATCAGCGGCCGGTGCTTCCGGTAATGCCGTTTACCGGGATGCTATACGA
GAAATTCGCACCGAGGTTGCAGCTGGTATGCAAATGAACCTTGCGATGCGAAATGTAAACGTATTTCCCGATATGGTTAT
TCAAATGGTTAGCATTGGTGAGGAATCTGGTGCCTTGGATGATATGCTTGCCAAGGTCGCGACCGTTTATGAACAGGAAG
TTGATGATGCGGTAGACGGATTAACTGCCCTGCTTGAACCTATGATTATGGCGGTGTTAGGTGTGGTGATTGGTGGCCTG
ATTATTGCCATGTACCTGCCTATTTTCCAAATTGGTATGGTTGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(285-407)

Type II secretion system (T2SS), protein F (T2SSF)

(82-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A516H9F6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

60.934

98.072

0.598
  pilC Acinetobacter baumannii D1279779

56.145

100

0.561
  pilC Acinetobacter baylyi ADP1

55.501

98.554

0.547
  pilC Legionella pneumophila strain ERS1305867

51.122

96.627

0.494
  pilC Vibrio cholerae strain A1552

44.307

97.349

0.431
  pilG Neisseria meningitidis 44/76-A

44.307

97.349

0.431
  pilG Neisseria gonorrhoeae MS11

44.059

97.349

0.429
  pilC Vibrio campbellii strain DS40M4

43.641

96.627

0.422

Multiple sequence alignment