Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   FDP16_RS08135 Genome accession   NZ_CP040798
Coordinates   1636481..1637161 (-) Length   226 a.a.
NCBI ID   WP_176799270.1    Uniprot ID   A0A7H8V244
Organism   Streptococcus sanguinis strain CGMH058     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1631481..1642161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS08120 (FDP16_08450) holA 1631792..1632838 (-) 1047 WP_176799268.1 DNA polymerase III subunit delta -
  FDP16_RS08125 (FDP16_08455) - 1633086..1634131 (-) 1046 Protein_1588 DUF805 domain-containing protein -
  FDP16_RS08130 (FDP16_08460) comEC/celB 1634257..1636497 (-) 2241 WP_176799269.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FDP16_RS08135 (FDP16_08465) comEA 1636481..1637161 (-) 681 WP_176799270.1 helix-hairpin-helix domain-containing protein Machinery gene
  FDP16_RS08140 (FDP16_08470) - 1637308..1637856 (-) 549 WP_176799800.1 HXXEE domain-containing protein -
  FDP16_RS08145 (FDP16_08475) - 1637929..1638669 (-) 741 WP_002900842.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FDP16_RS08150 (FDP16_08480) - 1638827..1641166 (+) 2340 WP_176799271.1 cation-translocating P-type ATPase -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24066.88 Da        Isoelectric Point: 4.9343

>NTDB_id=367231 FDP16_RS08135 WP_176799270.1 1636481..1637161(-) (comEA) [Streptococcus sanguinis strain CGMH058]
MLEEIIEKLKEYKLFVGLAVVGAVLGGFFLIKGNHQPQNQVTALSQEVTSSSSSADEEREKIVSKAKADEEESEQVTVDI
KGAVKNPGVYELRAGARVHEAIQKAGGLTADAEAKSINQAQKLTDEAVIYVAKIGEEGADVTQTGQHQAGASDSAGASGR
KSDKVNLNTATEAELQTISGIGQKRASDIIAYRESSGRFKSVDDLKKVSGIGDKTLEKLKEYVTVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=367231 FDP16_RS08135 WP_176799270.1 1636481..1637161(-) (comEA) [Streptococcus sanguinis strain CGMH058]
ATGCTTGAAGAAATCATTGAAAAGTTGAAAGAATACAAGCTCTTTGTTGGTCTAGCAGTAGTTGGCGCTGTGCTAGGTGG
TTTTTTCCTCATCAAGGGAAATCATCAGCCGCAAAATCAGGTAACCGCCTTAAGTCAGGAAGTAACTTCCTCATCCAGCT
CAGCTGATGAAGAAAGAGAAAAGATTGTTTCTAAGGCCAAGGCGGACGAAGAGGAAAGCGAGCAGGTCACTGTGGATATA
AAGGGCGCGGTCAAAAATCCTGGTGTCTATGAGCTGAGAGCAGGAGCGAGAGTCCATGAAGCCATCCAAAAAGCTGGCGG
ATTGACAGCAGACGCCGAGGCTAAGTCCATCAATCAGGCGCAAAAATTAACGGATGAAGCAGTAATCTACGTGGCAAAGA
TTGGTGAAGAAGGAGCCGATGTCACACAGACTGGCCAGCATCAAGCAGGAGCTTCTGATTCTGCTGGTGCCAGTGGTAGA
AAGTCAGACAAGGTCAATCTAAATACGGCGACAGAGGCTGAACTGCAGACTATTTCAGGCATTGGACAGAAGCGGGCTTC
TGACATCATCGCCTACCGCGAAAGCAGTGGCCGCTTCAAGTCAGTAGATGATCTGAAAAAGGTGTCAGGGATTGGAGATA
AGACCTTAGAAAAGCTGAAAGAATATGTTACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(78-131)

Helix-hairpin-helix motif (HHH_3)

(162-224)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8V244

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Streptococcus thermophilus LMD-9

50.644

100

0.522
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50.222

99.558

0.5
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50.222

99.558

0.5
  comEA/celA/cilE Streptococcus pneumoniae D39

50.222

99.558

0.5
  comEA/celA/cilE Streptococcus pneumoniae R6

50.222

99.558

0.5
  comEA/celA/cilE Streptococcus mitis NCTC 12261

50.222

99.558

0.5
  comEA/celA/cilE Streptococcus mitis SK321

49.558

100

0.496
  comEA Bacillus subtilis subsp. subtilis str. 168

42.534

97.788

0.416
  comEA Lactococcus lactis subsp. cremoris KW2

41.333

99.558

0.412
  comEA Latilactobacillus sakei subsp. sakei 23K

34.855

100

0.372

Multiple sequence alignment