Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   FDP16_RS08130 Genome accession   NZ_CP040798
Coordinates   1634257..1636497 (-) Length   746 a.a.
NCBI ID   WP_176799269.1    Uniprot ID   A0A7H8V2A4
Organism   Streptococcus sanguinis strain CGMH058     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1629257..1641497
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS08110 (FDP16_08440) - 1630108..1631052 (+) 945 WP_176799267.1 IS30 family transposase -
  FDP16_RS08115 (FDP16_08445) sodA 1631124..1631729 (-) 606 WP_002906995.1 superoxide dismutase SodA -
  FDP16_RS08120 (FDP16_08450) holA 1631792..1632838 (-) 1047 WP_176799268.1 DNA polymerase III subunit delta -
  FDP16_RS08125 (FDP16_08455) - 1633086..1634131 (-) 1046 Protein_1588 DUF805 domain-containing protein -
  FDP16_RS08130 (FDP16_08460) comEC/celB 1634257..1636497 (-) 2241 WP_176799269.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FDP16_RS08135 (FDP16_08465) comEA 1636481..1637161 (-) 681 WP_176799270.1 helix-hairpin-helix domain-containing protein Machinery gene
  FDP16_RS08140 (FDP16_08470) - 1637308..1637856 (-) 549 WP_176799800.1 HXXEE domain-containing protein -
  FDP16_RS08145 (FDP16_08475) - 1637929..1638669 (-) 741 WP_002900842.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FDP16_RS08150 (FDP16_08480) - 1638827..1641166 (+) 2340 WP_176799271.1 cation-translocating P-type ATPase -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 85044.37 Da        Isoelectric Point: 9.2708

>NTDB_id=367230 FDP16_RS08130 WP_176799269.1 1634257..1636497(-) (comEC/celB) [Streptococcus sanguinis strain CGMH058]
MLQWIKKLPLAPIYLAFILVWAYFAVYSGSSLAYFGLGVLLLRLFFSYPLKKSLAALAFLSLFVLFFLLRRGMAEQAFRQ
EPPSASSVQVLPDTIKVNGDSLSFRGRTDGRLYQVFYKIKSASEKEVFQQLTDLVVLDMEAEFEQAQQQRNFSGFDYQAY
LKSQGIYRTLKINKIQSLRPISSLNPLDWLSVWRRKALVYIRNNFPSPMSHYMTGLLFGDLDTEFAEMSDLYSSLGIIHL
FALSGMQVGFFLDGFRRILLRLGMKRETVNTLQLPFSFIYAGLTGFSVSVVRSLVQKLLAQQGLTRMDNFALTLMLLFII
MPNFLLTAGGVLSCAYAFLISMMDFEELSPFRKLLAESLTISLGILPILIYYFSEFQPWSVILTFLFSLLFDLLMLPGLT
LIFILSPMIKITQVNFFFQILEDVIRWVADFAPRPLIFGKPNLWLLVSLLLVLALIYDFRRKKSWLLSLSLLALLLFFLT
KHPLQNEITVVDIGQGDSIFLRDWQGRTILIDVGGRVELGKKEKWQERQTSSNAEKTLIPYLKSRGVGSLDVLILTHTDT
DHMGDMLEVAKHFSIKEVYVSKGSLTQPDFVQKLEQIETSVHVVKVGDEIPVFDSALQVLYPSGTGDGGNDDSIVLYGEF
FQTKFLFTGDLERKGETELLQRFPQLKADVLKAGHHGSKGSSSPEFLEQIQPKLALISAGQNNRYRHPHQETLQRFEKLN
TAIYRTDQQGAVRLIGWNSWRIETVH

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=367230 FDP16_RS08130 WP_176799269.1 1634257..1636497(-) (comEC/celB) [Streptococcus sanguinis strain CGMH058]
ATGTTACAGTGGATTAAAAAGCTACCCCTCGCCCCTATCTATCTGGCTTTCATCCTTGTATGGGCCTATTTTGCCGTCTA
TTCTGGTAGTTCCTTGGCTTATTTTGGGCTGGGTGTCCTTCTGCTTCGTCTCTTTTTCAGCTATCCCCTCAAGAAAAGTC
TGGCTGCTTTGGCATTCCTGTCCCTTTTTGTCCTCTTTTTCTTGCTTCGTCGGGGAATGGCAGAGCAGGCCTTTAGGCAG
GAACCTCCTTCAGCTAGCTCGGTTCAAGTTTTGCCGGATACGATCAAAGTCAATGGAGATTCCCTATCCTTTCGAGGGCG
AACGGACGGTCGGCTTTATCAAGTCTTCTACAAGATTAAATCAGCCAGTGAAAAGGAAGTTTTTCAGCAACTGACAGATT
TGGTTGTCCTTGATATGGAAGCAGAGTTTGAACAGGCGCAGCAGCAACGAAATTTTTCAGGCTTTGACTATCAGGCTTAT
TTAAAGAGTCAGGGGATTTACCGTACCTTAAAAATCAATAAGATTCAGTCACTAAGACCAATTTCCAGCCTTAATCCACT
CGATTGGCTGTCTGTCTGGCGCAGAAAAGCGCTGGTTTACATTAGAAATAATTTTCCTAGTCCAATGAGCCATTACATGA
CTGGACTCTTATTTGGTGACTTGGATACAGAGTTTGCAGAAATGAGTGACCTCTATTCTAGCTTGGGTATCATCCATTTG
TTTGCCTTGTCTGGTATGCAGGTAGGTTTCTTTTTGGATGGTTTTCGCAGAATTCTTCTAAGGTTGGGGATGAAGAGGGA
GACAGTAAACACCTTGCAGCTGCCTTTTTCATTTATCTATGCTGGACTGACGGGCTTTTCTGTTTCTGTCGTCAGAAGCT
TAGTTCAGAAGTTATTGGCCCAGCAAGGCCTGACCAGAATGGATAATTTTGCTCTGACACTGATGCTTCTCTTTATCATC
ATGCCCAATTTTCTTCTGACAGCTGGCGGTGTCTTGTCCTGCGCTTATGCTTTTTTGATTTCTATGATGGATTTTGAGGA
GTTGTCGCCGTTTCGGAAGCTTTTAGCGGAAAGTCTGACTATTTCATTGGGGATTTTGCCTATACTAATCTACTATTTTT
CTGAATTTCAGCCCTGGTCCGTGATTTTAACTTTTCTATTTTCACTACTCTTTGACCTGCTGATGCTGCCAGGGTTAACC
CTCATTTTTATTTTGTCACCAATGATAAAAATCACTCAAGTCAATTTTTTCTTTCAGATACTTGAAGATGTGATTCGTTG
GGTAGCTGATTTTGCTCCGCGTCCTTTGATTTTTGGGAAGCCCAACCTCTGGTTACTGGTCTCTCTGCTTTTGGTTTTGG
CTTTAATCTATGACTTTCGGAGAAAGAAAAGCTGGCTTTTGTCTCTTAGTTTGCTTGCTCTTCTCTTATTTTTTCTAACA
AAGCATCCGCTGCAAAATGAGATTACAGTGGTGGATATTGGTCAAGGTGATAGCATTTTTCTCAGGGACTGGCAGGGCAG
GACGATTTTGATTGACGTAGGAGGACGAGTTGAGCTAGGAAAGAAAGAGAAGTGGCAAGAACGACAGACTTCATCCAATG
CAGAAAAGACCTTGATTCCCTATCTCAAAAGCCGAGGGGTTGGTAGTCTGGATGTATTGATTCTGACTCATACCGATACC
GACCACATGGGCGATATGCTGGAGGTAGCTAAGCATTTTTCTATCAAGGAAGTCTATGTTTCCAAAGGAAGTTTGACTCA
GCCTGATTTTGTTCAAAAGCTGGAGCAGATAGAAACTTCTGTCCATGTCGTAAAAGTTGGAGATGAGATTCCGGTATTTG
ACTCGGCTTTGCAGGTTCTCTATCCTAGTGGGACAGGCGACGGTGGAAATGATGATTCGATTGTACTCTACGGGGAGTTC
TTTCAGACAAAATTTTTGTTTACAGGTGATTTGGAAAGGAAAGGAGAAACTGAACTGCTGCAGCGATTTCCTCAACTGAA
AGCAGATGTCTTAAAAGCAGGGCATCATGGCTCCAAAGGCTCTTCCAGTCCAGAGTTTTTAGAGCAAATTCAGCCGAAAC
TGGCCTTGATATCAGCTGGCCAGAATAATCGTTATCGACATCCGCATCAGGAAACTTTGCAAAGATTTGAGAAGCTTAAT
ACAGCCATCTATCGAACTGACCAGCAGGGGGCTGTTCGTTTGATTGGTTGGAATTCCTGGAGGATTGAAACAGTTCACTG
A

Domains

Predicted by InterproScan.

Competence protein (Competence)

(216-461)

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8V2A4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

57.831

100

0.579
  comEC/celB Streptococcus mitis NCTC 12261

57.507

100

0.575
  comEC/celB Streptococcus pneumoniae TIGR4

56.76

100

0.568
  comEC/celB Streptococcus pneumoniae Rx1

56.225

100

0.563
  comEC/celB Streptococcus pneumoniae D39

56.225

100

0.563
  comEC/celB Streptococcus pneumoniae R6

56.225

100

0.563
  comEC Lactococcus lactis subsp. cremoris KW2

48.725

99.866

0.487

Multiple sequence alignment