Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M594_RS08905 Genome accession   NZ_CP047883
Coordinates   1861104..1862360 (-) Length   418 a.a.
NCBI ID   WP_173876608.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V3-A4     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1856104..1867360
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS08885 (M594_08925) - 1856949..1857419 (-) 471 WP_173876605.1 MarR family winged helix-turn-helix transcriptional regulator -
  M594_RS08890 (M594_08930) - 1857597..1858313 (-) 717 WP_000532877.1 YebC/PmpR family DNA-binding transcriptional regulator -
  M594_RS08895 (M594_08935) - 1858410..1859780 (-) 1371 WP_173876606.1 MATE family efflux transporter -
  M594_RS08900 (M594_08940) recA 1859895..1861049 (-) 1155 WP_173876607.1 recombinase RecA -
  M594_RS08905 (M594_08945) cinA 1861104..1862360 (-) 1257 WP_173876608.1 competence/damage-inducible protein A Machinery gene
  M594_RS08910 (M594_08950) brpA 1862428..1863468 (-) 1041 WP_173876609.1 biofilm formation/cell division transcriptional regulator BrpA -
  M594_RS08915 (M594_08955) - 1863473..1863994 (-) 522 WP_173876610.1 GNAT family N-acetyltransferase -
  M594_RS08920 (M594_08960) tsaE 1863984..1864427 (-) 444 WP_173876611.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  M594_RS08925 (M594_08965) comM 1864522..1865142 (-) 621 WP_173876612.1 hypothetical protein Regulator
  M594_RS08930 (M594_08970) ndk 1865278..1865697 (-) 420 WP_173876613.1 nucleoside-diphosphate kinase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45243.45 Da        Isoelectric Point: 4.6295

>NTDB_id=366344 M594_RS08905 WP_173876608.1 1861104..1862360(-) (cinA) [Streptococcus mitis strain S022-V3-A4]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKELVFDSQAQEKLDVFFTQRPDYARTPNNERQAQIVDGATPLPNETGLAVGGILEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGRKLYSRVLRFFGIGESQLVTILSDLIDNQTDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDRQTFEGISLRDLCYGYGEETSLASIVVEELKRQGKTITAAESLTAGLFQARVADFSGASSIFKGGFVTYSLEEKSRML
DIPAKDLEEHGVVSEFTAQKMAEQARIKTQSDFGLSLTGVAGPDSLEGHPAGTVFIGLAQEHGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=366344 M594_RS08905 WP_173876608.1 1861104..1862360(-) (cinA) [Streptococcus mitis strain S022-V3-A4]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAATACCAATGCCCAGTTTTTATCAGA
AAAACTAGCAGAGATTGGGGTAGATGTTTATTTTCAGACGGCTGTAGGAGACAATGAAGCTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTAACAGGTGGTTTGGGGCCAACTGAGGACGACCTAACTAAACAAACT
CTAGCTAAATTTTTAGGGAAAGAATTAGTCTTCGATTCTCAGGCTCAGGAGAAGTTGGATGTCTTTTTTACCCAGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCCCAAATTGTAGATGGAGCGACTCCACTGCCAAACGAAACCGGAC
TGGCTGTAGGAGGAATATTGGAAGTCGATGGAGTGACCTACGTTGTCCTTCCAGGTCCACCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGAAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
AAGTCAGTTGGTTACGATTTTGTCTGATTTGATTGATAATCAAACAGATCCGACTTTGGCCCCTTATGCCAAGACAGGAG
AAGTTACTCTGCGTCTGTCAACAAAAGCTAGCAGCCAAGAAGAGGCGAATCAAGCGCTAGATATCTTGGAAAATCAAATC
TTGGACCGCCAGACTTTCGAAGGAATTTCTTTACGAGACCTTTGTTATGGTTATGGGGAAGAAACTAGTTTAGCTAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACTATCACGGCTGCAGAGAGTTTGACGGCTGGTCTTTTCCAAGCTAGGG
TAGCGGATTTTTCGGGTGCTTCAAGTATATTCAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGGATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAAAAGATGGCTGAGCAGGCACGAAT
CAAGACCCAGTCTGATTTTGGCCTTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACATCCAGCTGGGACAG
TTTTCATAGGCTTGGCTCAAGAGCATGGAACTGAGGTCATAAAGGTCAATATTGGAGGCAGAAGTCGAGCAGATGTACGT
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterProScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis NCTC 12261

96.411

100

0.964
  cinA Streptococcus mitis SK321

96.172

100

0.962
  cinA Streptococcus pneumoniae TIGR4

94.498

100

0.945
  cinA Streptococcus pneumoniae R36A

93.78

100

0.938
  cinA Streptococcus pneumoniae Rx1

93.78

100

0.938
  cinA Streptococcus pneumoniae R6

93.78

100

0.938
  cinA Streptococcus pneumoniae D39

93.541

100

0.935
  cinA Streptococcus mutans UA159

72.488

100

0.725
  cinA Streptococcus suis isolate S10

54.567

99.522

0.543
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment