Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SMUNN2025_RS00965 Genome accession   NC_013928
Coordinates   204599..205630 (+) Length   343 a.a.
NCBI ID   WP_255262945.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 199599..210630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS00955 (SmuNN2025_0170) - 203207..203590 (+) 384 WP_002263434.1 DUF1033 family protein -
  SMUNN2025_RS00960 (SmuNN2025_0171) comYA 203722..204663 (+) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  SMUNN2025_RS00965 (SmuNN2025_0172) comYB 204599..205630 (+) 1032 WP_255262945.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMUNN2025_RS00970 (SmuNN2025_0173) comYC 205630..205944 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMUNN2025_RS00975 (SmuNN2025_0174) comYD 205931..206335 (+) 405 WP_002273742.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMUNN2025_RS00980 (SmuNN2025_0175) comYE 206307..206600 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMUNN2025_RS00985 (SmuNN2025_0176) comYF 206587..207021 (+) 435 WP_002264245.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMUNN2025_RS00990 (SmuNN2025_0177) comYG 206999..207388 (+) 390 WP_002278009.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMUNN2025_RS00995 (SmuNN2025_0178) comYH 207443..208396 (+) 954 WP_002278010.1 class I SAM-dependent methyltransferase Machinery gene
  SMUNN2025_RS01000 (SmuNN2025_0179) - 208455..209654 (+) 1200 WP_002265895.1 acetate kinase -
  SMUNN2025_RS01005 (SmuNN2025_0180) - 210215..210460 (+) 246 WP_002278011.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39816.40 Da        Isoelectric Point: 9.5151

>NTDB_id=36559 SMUNN2025_RS00965 WP_255262945.1 204599..205630(+) (comYB) [Streptococcus mutans NN2025]
MTFLQQDISLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEIYTKKMRQGLLNGLHLAEIMSSLG
FSDDVVTQLALSEVHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVAIMLGLKNYLLPQLERGNFATRLISN
FPILFLLGCCFFILLVGIFTFFSRKISRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=36559 SMUNN2025_RS00965 WP_255262945.1 204599..205630(+) (comYB) [Streptococcus mutans NN2025]
ATGACCTTTTTACAGCAGGATATATCACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATCCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAATATACACAAAGAAAATGCGACAAGGGTTGTTGAATGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAGTTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
TTATCTAAATAATCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCGATCATTTTATTGATTTTTCTTG
TCGCTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAGGGGAAATTTTGCGACTCGGTTGATTTCTAAT
TTCCCAATACTTTTCTTGCTGGGATGTTGCTTTTTTATTTTACTAGTTGGCATTTTTACTTTCTTTTCACGAAAGATCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAA
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCTCTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGCCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCAAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

99.708

100

0.997
  comYB Streptococcus mutans UA140

99.125

100

0.991
  comYB Streptococcus gordonii str. Challis substr. CH1

60.058

100

0.601
  comGB/cglB Streptococcus mitis NCTC 12261

58.407

98.834

0.577
  comGB/cglB Streptococcus mitis SK321

56.548

97.959

0.554
  comGB/cglB Streptococcus pneumoniae Rx1

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae D39

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae R6

55.952

97.959

0.548
  comGB/cglB Streptococcus pneumoniae TIGR4

55.952

97.959

0.548
  comGB Lactococcus lactis subsp. cremoris KW2

51.632

98.251

0.507

Multiple sequence alignment