Detailed information NTG0036561

Bioinformatically predicted

Overview

• Name: comYD
• Type: Machinery gene
• Locus tag: SMUNN2025_RS00975
• Genome accession: NC_013928
• Coordinates: 205931..206335 (+)
• Length: 134 a.a.
• NCBI ID: WP_002273742.1
• Uniprot ID: -
• Organism: Streptococcus mutans NN2025
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 200931..211335

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUNN2025_RS00955 (SmuNN2025_0170)	-	203207..203590 (+)	384	WP_002263434.1	DUF1033 family protein	-
SMUNN2025_RS00960 (SmuNN2025_0171)	comYA	203722..204663 (+)	942	WP_002263435.1	competence type IV pilus ATPase ComGA	Machinery gene
SMUNN2025_RS00965 (SmuNN2025_0172)	comYB	204599..205630 (+)	1032	WP_255262945.1	competence type IV pilus assembly protein ComGB	Machinery gene
SMUNN2025_RS00970 (SmuNN2025_0173)	comYC	205630..205944 (+)	315	WP_002263437.1	competence type IV pilus major pilin ComGC	Machinery gene
SMUNN2025_RS00975 (SmuNN2025_0174)	comYD	205931..206335 (+)	405	WP_002273742.1	competence type IV pilus minor pilin ComGD	Machinery gene
SMUNN2025_RS00980 (SmuNN2025_0175)	comYE	206307..206600 (+)	294	WP_002263439.1	competence type IV pilus minor pilin ComGE	Machinery gene
SMUNN2025_RS00985 (SmuNN2025_0176)	comYF	206587..207021 (+)	435	WP_002264245.1	competence type IV pilus minor pilin ComGF	Machinery gene
SMUNN2025_RS00990 (SmuNN2025_0177)	comYG	206999..207388 (+)	390	WP_002278009.1	competence type IV pilus minor pilin ComGG	Machinery gene
SMUNN2025_RS00995 (SmuNN2025_0178)	comYH	207443..208396 (+)	954	WP_002278010.1	class I SAM-dependent methyltransferase	Machinery gene
SMUNN2025_RS01000 (SmuNN2025_0179)	-	208455..209654 (+)	1200	WP_002265895.1	acetate kinase	-
SMUNN2025_RS01005 (SmuNN2025_0180)	-	210215..210460 (+)	246	WP_002278011.1	helix-turn-helix transcriptional regulator	-
SMUNN2025_RS01010 (SmuNN2025_0181)	-	210429..210869 (+)	441	WP_002263445.1	hypothetical protein	-

Sequence

Protein

• Length: 134 a.a.
• Molecular weight: 15437.78 Da
• Isoelectric Point: 9.2271

>NTDB_id=36561 SMUNN2025_RS00975 WP_002273742.1 205931..206335(+) (comYD) [Streptococcus mutans NN2025]
MSRIKAFTLIESLVTLAITSFLILSFSGSILQTFAKVEEHLFFLSFEHLYRDTQKLSVYQRQDMTLILKSEYISNGVEVL
KIPKDVKLERNKTLHFDQAGGNSSLEKLVFQTSDEKRVTYQLYIGSGQYKKTES

Nucleotide

• Length: 405 bp

>NTDB_id=36561 SMUNN2025_RS00975 WP_002273742.1 205931..206335(+) (comYD) [Streptococcus mutans NN2025]
ATGTCGCGAATTAAAGCTTTTACGCTTATAGAAAGTTTAGTGACTTTGGCAATTACTAGTTTTTTGATTTTAAGCTTTTC
AGGTAGTATACTTCAAACGTTTGCCAAAGTAGAAGAGCATCTCTTTTTTCTTTCTTTTGAACATCTTTACCGTGACACGC
AAAAACTTAGTGTTTATCAAAGACAAGATATGACTTTAATATTAAAAAGCGAATATATCTCAAATGGTGTTGAAGTACTT
AAAATCCCTAAGGATGTCAAACTAGAGAGGAATAAAACTTTGCACTTTGATCAGGCAGGAGGAAATTCTTCTTTAGAAAA
ACTTGTTTTTCAAACATCTGATGAAAAAAGAGTTACTTATCAATTATATATAGGAAGTGGTCAGTATAAAAAAACAGAAA
GTTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (1-25)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYD	Streptococcus mutans UA140	98.507	100	0.985
comYD	Streptococcus mutans UA159	98.507	100	0.985
comYD	Streptococcus gordonii str. Challis substr. CH1	50.388	96.269	0.485
comGD/cglD	Streptococcus mitis NCTC 12261	49.612	96.269	0.478
comGD/cglD	Streptococcus pneumoniae Rx1	49.219	95.522	0.47
comGD/cglD	Streptococcus pneumoniae D39	49.219	95.522	0.47
comGD/cglD	Streptococcus pneumoniae R6	49.219	95.522	0.47
comGD/cglD	Streptococcus pneumoniae TIGR4	48.438	95.522	0.463
comGD/cglD	Streptococcus mitis SK321	48.438	95.522	0.463
comGD	Lactococcus lactis subsp. cremoris KW2	38.636	98.507	0.381