Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   SMUNN2025_RS00995 Genome accession   NC_013928
Coordinates   207443..208396 (+) Length   317 a.a.
NCBI ID   WP_002278010.1    Uniprot ID   A0A829BNJ9
Organism   Streptococcus mutans NN2025     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 202443..213396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS00955 (SmuNN2025_0170) - 203207..203590 (+) 384 WP_002263434.1 DUF1033 family protein -
  SMUNN2025_RS00960 (SmuNN2025_0171) comYA 203722..204663 (+) 942 WP_002263435.1 competence type IV pilus ATPase ComGA Machinery gene
  SMUNN2025_RS00965 (SmuNN2025_0172) comYB 204599..205630 (+) 1032 WP_255262945.1 competence type IV pilus assembly protein ComGB Machinery gene
  SMUNN2025_RS00970 (SmuNN2025_0173) comYC 205630..205944 (+) 315 WP_002263437.1 competence type IV pilus major pilin ComGC Machinery gene
  SMUNN2025_RS00975 (SmuNN2025_0174) comYD 205931..206335 (+) 405 WP_002273742.1 competence type IV pilus minor pilin ComGD Machinery gene
  SMUNN2025_RS00980 (SmuNN2025_0175) comYE 206307..206600 (+) 294 WP_002263439.1 competence type IV pilus minor pilin ComGE Machinery gene
  SMUNN2025_RS00985 (SmuNN2025_0176) comYF 206587..207021 (+) 435 WP_002264245.1 competence type IV pilus minor pilin ComGF Machinery gene
  SMUNN2025_RS00990 (SmuNN2025_0177) comYG 206999..207388 (+) 390 WP_002278009.1 competence type IV pilus minor pilin ComGG Machinery gene
  SMUNN2025_RS00995 (SmuNN2025_0178) comYH 207443..208396 (+) 954 WP_002278010.1 class I SAM-dependent methyltransferase Machinery gene
  SMUNN2025_RS01000 (SmuNN2025_0179) - 208455..209654 (+) 1200 WP_002265895.1 acetate kinase -
  SMUNN2025_RS01005 (SmuNN2025_0180) - 210215..210460 (+) 246 WP_002278011.1 helix-turn-helix transcriptional regulator -
  SMUNN2025_RS01010 (SmuNN2025_0181) - 210429..210869 (+) 441 WP_002263445.1 hypothetical protein -
  SMUNN2025_RS01015 (SmuNN2025_0182) - 210922..211584 (+) 663 WP_002263446.1 type II CAAX endopeptidase family protein -
  SMUNN2025_RS01020 (SmuNN2025_0183) proC 211669..212439 (-) 771 WP_002263447.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 36289.55 Da        Isoelectric Point: 5.0963

>NTDB_id=36565 SMUNN2025_RS00995 WP_002278010.1 207443..208396(+) (comYH) [Streptococcus mutans NN2025]
MDFEKIEAAYNLLLDNCQRLETQLHTHLYDALIEQNACYLGAEGADDFIKENNKKLRQLNLSKEEWRRSFQFIFIKATQS
QQLQSNHQFTPDSIGFIILYLLEGLTNKSQLDIIEIGSGTGNLAETIVNNSSKSIDYMGIEVDDLLIDLSASIADVLDSS
VHFVQEDAVRPQILKESDIIISDLPVGFYPDDKIAQRYQVAAKLGHTYAHHLLMEQSLKYLKKEGLAIFLAPVDLLTSEQ
SPLLKKWLQNNVTILSVISLPEAIFKQKSNIKSIFVLKKQSQQSLESFVYPLTDLQDPEVLRRFMKNFKKWKEDNVF

Nucleotide


Download         Length: 954 bp        

>NTDB_id=36565 SMUNN2025_RS00995 WP_002278010.1 207443..208396(+) (comYH) [Streptococcus mutans NN2025]
ATGGATTTTGAAAAAATAGAAGCTGCCTATAACTTACTGTTAGATAATTGTCAAAGGCTGGAAACTCAACTTCATACTCA
CCTTTATGATGCCTTAATTGAGCAAAATGCTTGCTATCTAGGTGCTGAAGGTGCTGATGATTTTATTAAAGAAAATAATA
AAAAACTGCGTCAGCTTAATCTAAGTAAAGAAGAGTGGCGTCGTAGTTTTCAATTTATTTTTATTAAGGCTACTCAAAGT
CAGCAATTACAGTCAAATCACCAATTTACACCAGATAGTATTGGTTTTATTATTCTTTATTTATTGGAAGGTTTAACAAA
TAAGAGTCAGTTAGACATCATTGAAATTGGTTCTGGGACAGGAAATCTTGCAGAGACTATTGTGAATAACAGTTCAAAAA
GCATTGATTATATGGGGATTGAGGTTGACGATCTGTTAATTGATTTATCAGCAAGTATTGCCGATGTATTGGATTCTTCT
GTGCATTTTGTTCAAGAAGATGCAGTGCGGCCTCAGATTTTAAAAGAAAGTGATATCATTATCAGTGATCTGCCAGTTGG
CTTTTATCCCGATGATAAAATTGCTCAGCGTTATCAGGTTGCAGCCAAGTTAGGACATACTTATGCACATCATCTTTTGA
TGGAGCAATCGCTTAAGTATTTAAAAAAAGAGGGACTTGCTATTTTTTTAGCGCCAGTGGATCTTTTAACTAGTGAGCAG
AGTCCTTTGCTTAAAAAGTGGTTACAGAACAATGTAACTATTTTATCCGTTATTTCTTTACCTGAGGCAATTTTTAAACA
GAAAAGTAATATAAAGTCAATCTTTGTCTTAAAGAAACAATCGCAACAAAGTTTGGAAAGTTTTGTCTATCCTTTGACAG
ATTTACAAGACCCCGAAGTTTTAAGACGATTTATGAAAAATTTTAAAAAGTGGAAGGAAGATAATGTCTTTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(77-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A829BNJ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

99.369

100

0.994
  comYH Streptococcus mutans UA140

98.738

100

0.987

Multiple sequence alignment