Detailed information NTG0362681

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: FD735_RS09790
• Genome accession: NZ_CP040231
• Coordinates: 1896297..1897493 (+)
• Length: 398 a.a.
• NCBI ID: WP_070569607.1
• Uniprot ID: -
• Organism: Streptococcus sp. 1643
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1891297..1902493

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD735_RS09750 (FD735_09750)	-	1892358..1892900 (+)	543	WP_070569601.1	TetR/AcrR family transcriptional regulator	-
FD735_RS09765 (FD735_09765)	comE	1893136..1893888 (-)	753	WP_000866079.1	competence system response regulator transcription factor ComE	Regulator
FD735_RS09770 (FD735_09770)	comD	1893885..1895204 (-)	1320	WP_139659086.1	competence system sensor histidine kinase ComD	Regulator
FD735_RS09775 (FD735_09775)	comC/comC2	1895225..1895350 (-)	126	WP_000799678.1	competence-stimulating peptide ComC	Regulator
FD735_RS09785 (FD735_09785)	rlmH	1895632..1896111 (-)	480	WP_070569604.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
FD735_RS09790 (FD735_09790)	htrA	1896297..1897493 (+)	1197	WP_070569607.1	S1C family serine protease	Regulator
FD735_RS09795 (FD735_09795)	spo0J	1897551..1898309 (+)	759	WP_139659087.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 42042.85 Da
• Isoelectric Point: 6.3586

>NTDB_id=362681 FD735_RS09790 WP_070569607.1 1896297..1897493(+) (htrA) [Streptococcus sp. 1643]
MKHLQKFYKKGVKVLIIILIGFLSGALGSFVTLQLYQKQGNQATNNNSGTVTQTSYKNENSTTQAVNKVKDAVVSIITYS
SSSSRQSSVFNADETNSDSDNQQIASEGSGVIYKKDDKDAYLVTNTHVINGASKVDIRLADGTKVPGEIVGSDTFSDIAV
VKISSEKVTTVAEFGDSSQLSVGETAIAIGSPLGSEYANTVTQGIISSLNRNVSLKSEDGQAISTKAIQTDTAINPGNSG
GPLVNIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDAQNIIKQLESDGKVTRPALGIQMVNLSNVGASDLRKLNIPSGL
TSGVVVRSVQNNMPANGHLQKYDVITKVDDKEIASSTDLQHALYNHAIGDTIKVTYYRNGKEETTSIKLDKNSSDLES

Nucleotide

• Length: 1197 bp

>NTDB_id=362681 FD735_RS09790 WP_070569607.1 1896297..1897493(+) (htrA) [Streptococcus sp. 1643]
ATGAAACACTTACAAAAATTTTACAAAAAAGGAGTTAAAGTTCTAATAATCATTCTAATCGGATTTTTAAGTGGTGCCTT
AGGAAGTTTCGTAACATTACAACTTTATCAAAAACAAGGAAATCAAGCTACAAATAATAATTCTGGCACTGTCACTCAAA
CATCCTATAAGAATGAAAATTCAACCACTCAAGCAGTAAATAAAGTTAAGGATGCTGTTGTCTCAATCATTACTTATTCT
TCTTCTAGCAGTAGACAAAGTAGTGTATTTAATGCTGACGAAACTAATTCTGATTCAGACAATCAACAAATCGCAAGTGA
GGGATCAGGTGTTATCTATAAAAAGGATGATAAAGATGCCTATCTTGTAACTAATACTCACGTTATCAATGGAGCTTCAA
AAGTTGATATCCGCTTAGCAGATGGTACTAAGGTTCCTGGTGAAATTGTCGGATCTGATACCTTCTCTGATATTGCTGTC
GTTAAAATTTCTTCCGAAAAAGTTACAACAGTCGCAGAATTTGGAGATTCAAGTCAACTTAGTGTTGGAGAAACAGCGAT
TGCTATCGGTAGTCCTCTAGGTTCAGAATATGCTAATACAGTTACACAGGGGATTATTTCAAGTCTTAATCGAAATGTTT
CTCTAAAATCTGAAGATGGTCAAGCTATTTCAACAAAAGCCATTCAAACAGATACAGCCATTAACCCTGGTAACTCTGGT
GGTCCACTTGTAAATATTCAAGGACAAGTAATTGGTATTACATCAAGTAAAATTGCAAGTAATGGTGGAACATCTGTAGA
AGGTCTTGGTTTTGCAATTCCTTCAAACGATGCACAAAATATCATTAAACAACTTGAAAGTGATGGTAAAGTGACTCGTC
CTGCTCTTGGAATTCAAATGGTCAATCTGTCAAATGTTGGAGCTAGTGATCTTAGAAAACTTAACATTCCAAGTGGCCTC
ACTTCAGGTGTAGTTGTTCGATCTGTTCAAAACAATATGCCAGCAAATGGACATCTTCAAAAATATGATGTCATTACCAA
AGTTGACGACAAAGAGATTGCCTCATCAACAGACCTACAACACGCTCTTTACAATCATGCTATCGGAGATACGATCAAAG
TAACCTACTACCGTAACGGTAAGGAGGAAACAACCTCAATTAAACTAGATAAGAATTCTAGTGATTTAGAGTCTTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (294-389)

• Peptidase family M50 (Peptidase_M50) (219-393)

• Trypsin-like peptidase domain (Trypsin_2) (108-253)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mitis NCTC 12261	83.166	100	0.832
htrA	Streptococcus pneumoniae Rx1	82.412	100	0.824
htrA	Streptococcus pneumoniae D39	82.412	100	0.824
htrA	Streptococcus pneumoniae R6	82.412	100	0.824
htrA	Streptococcus pneumoniae TIGR4	82.412	100	0.824
htrA	Streptococcus gordonii str. Challis substr. CH1	66.915	100	0.676
htrA	Streptococcus mutans UA159	54.822	98.995	0.543