Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   E2P79_RS16445 Genome accession   NZ_CP039611
Coordinates   3481534..3482772 (+) Length   412 a.a.
NCBI ID   WP_050666599.1    Uniprot ID   A0A0S2SE58
Organism   Aeromonas schubertii strain LF1708     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3476534..3487772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E2P79_RS16420 (E2P79_16420) ampD 3477164..3477736 (-) 573 WP_136614163.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  E2P79_RS16425 (E2P79_16425) - 3477761..3478243 (+) 483 WP_136614164.1 TIGR02281 family clan AA aspartic protease -
  E2P79_RS16430 (E2P79_16430) nadC 3478249..3479109 (+) 861 WP_136614165.1 carboxylating nicotinate-nucleotide diphosphorylase -
  E2P79_RS16435 (E2P79_16435) - 3479370..3479807 (+) 438 WP_136614166.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  E2P79_RS16440 (E2P79_16440) pilB 3479807..3481513 (+) 1707 WP_136614167.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  E2P79_RS16445 (E2P79_16445) pilC 3481534..3482772 (+) 1239 WP_050666599.1 type II secretion system F family protein Machinery gene
  E2P79_RS16450 (E2P79_16450) pilD 3482798..3483667 (+) 870 WP_136614168.1 A24 family peptidase Machinery gene
  E2P79_RS16455 (E2P79_16455) coaE 3483678..3484292 (+) 615 WP_136614169.1 dephospho-CoA kinase -
  E2P79_RS16460 (E2P79_16460) zapD 3484331..3485053 (+) 723 WP_050666596.1 cell division protein ZapD -
  E2P79_RS16465 (E2P79_16465) yacG 3485063..3485251 (+) 189 WP_050666595.1 DNA gyrase inhibitor YacG -
  E2P79_RS16470 (E2P79_16470) mutT 3485283..3485693 (-) 411 WP_050666594.1 8-oxo-dGTP diphosphatase MutT -

Sequence

Protein


Download         Length: 412 a.a.        Molecular weight: 45251.22 Da        Isoelectric Point: 9.3713

>NTDB_id=360089 E2P79_RS16445 WP_050666599.1 3481534..3482772(+) (pilC) [Aeromonas schubertii strain LF1708]
MATLAQKNKSPKISAFRWSGVNRKGQKVSGEMQADSVNTVKAELRKQGVTVSKVSKKSQGLFSKGAAKINTMDIAVITRQ
ITTMLSAGVPLVQTLQVIARSHEKATMRELVGEIAANVETGTPLSEALRQHPRQFDQLYCDLVEAGEQSGALETIFDRIA
TYREKTEALKSKIKKAMFYPTMVIIVAIVVTSILLLFVIPQFEDIFKSFGAELPAFTQFVIGISRFMQDWWYVFFGGTAL
VIFLYVRAWRASEKVRDRTDKFVLELPVVGMILHKAAMARFARTLATTFAAGIPLVDALISSAGASGNYVYRTAIMAIRN
EVIAGMQVNVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIAM
YLPIFKLGDVVG

Nucleotide


Download         Length: 1239 bp        

>NTDB_id=360089 E2P79_RS16445 WP_050666599.1 3481534..3482772(+) (pilC) [Aeromonas schubertii strain LF1708]
ATGGCAACGCTGGCTCAGAAAAATAAATCGCCCAAGATCTCCGCCTTTCGCTGGAGTGGCGTGAACCGCAAGGGACAGAA
AGTCTCCGGCGAGATGCAGGCCGACTCGGTCAATACCGTCAAGGCTGAGCTGCGCAAGCAGGGGGTGACCGTCTCCAAGG
TGAGCAAGAAGTCCCAGGGGCTCTTCTCCAAGGGCGCGGCCAAGATCAATACCATGGATATCGCCGTCATCACCCGCCAG
ATCACCACCATGCTCTCGGCCGGCGTGCCTCTGGTACAGACCCTTCAGGTCATCGCCCGCAGCCACGAGAAGGCAACCAT
GCGCGAGCTCGTCGGCGAGATCGCCGCCAATGTGGAGACGGGCACCCCCCTCTCCGAAGCCCTGCGCCAACACCCGCGCC
AGTTCGATCAGCTCTACTGCGACCTGGTGGAAGCCGGCGAACAATCGGGAGCTCTCGAGACCATTTTCGATCGCATCGCC
ACCTATCGAGAGAAGACCGAAGCACTCAAGTCGAAGATCAAGAAGGCCATGTTCTACCCCACCATGGTCATCATAGTGGC
CATCGTCGTGACCTCTATCCTGTTGTTGTTCGTCATCCCCCAGTTCGAGGATATCTTCAAGAGCTTCGGGGCCGAACTCC
CCGCCTTCACCCAGTTTGTCATCGGCATCTCACGCTTCATGCAAGACTGGTGGTATGTCTTCTTCGGCGGTACCGCCCTG
GTTATCTTCCTCTATGTGCGGGCATGGCGTGCCTCCGAGAAGGTACGAGACCGAACCGACAAGTTTGTGCTCGAGCTCCC
CGTGGTCGGCATGATACTGCACAAGGCGGCCATGGCCCGTTTTGCCCGCACCCTGGCCACCACCTTTGCCGCCGGTATTC
CGCTGGTTGACGCACTGATCTCCTCGGCCGGGGCCTCGGGCAACTATGTCTATCGCACCGCCATCATGGCCATTCGCAAC
GAAGTGATCGCCGGCATGCAGGTCAACGTCGCCATGCGCACGGTCGATCTCTTCCCCGATATGGTGATCCAGATGGTGAT
GATCGGCGAGGAATCGGGGGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGACCTCG
TCGATGGCCTGACCAGCCTGCTCGAACCCCTCATCATGGTGGTATTGGGGGTACTGGTAGGGGGCATGGTCATCGCCATG
TACCTGCCCATCTTCAAGCTGGGGGATGTGGTGGGTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(78-200)

Type II secretion system (T2SS), protein F (T2SSF)

(281-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0S2SE58

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

56.576

97.816

0.553
  pilC Acinetobacter baumannii D1279779

54.167

99.029

0.536
  pilC Acinetobacter baylyi ADP1

51.852

98.301

0.51
  pilC Legionella pneumophila strain ERS1305867

51.365

97.816

0.502
  pilC Vibrio cholerae strain A1552

47.512

97.573

0.464
  pilC Vibrio campbellii strain DS40M4

45.455

98.786

0.449
  pilG Neisseria meningitidis 44/76-A

41.927

93.204

0.391
  pilG Neisseria gonorrhoeae MS11

41.927

93.204

0.391

Multiple sequence alignment