Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   E3983_RS08265 Genome accession   NZ_CP038254
Coordinates   1852047..1853267 (+) Length   406 a.a.
NCBI ID   WP_135060608.1    Uniprot ID   A0AAX1EGV5
Organism   Legionella israelensis strain HL-0427-4011     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1847047..1858267
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3983_RS08240 (E3983_08240) - 1847064..1848200 (+) 1137 WP_135060606.1 HlyD family type I secretion periplasmic adaptor subunit -
  E3983_RS08245 (E3983_08245) - 1848222..1848797 (-) 576 WP_058502290.1 hypoxanthine-guanine phosphoribosyltransferase -
  E3983_RS08250 (E3983_08250) - 1848920..1849246 (-) 327 WP_058502289.1 DUF1820 family protein -
  E3983_RS08255 (E3983_08255) - 1849372..1850151 (-) 780 WP_167554556.1 methyltransferase domain-containing protein -
  E3983_RS08260 (E3983_08260) pilB 1850320..1852041 (+) 1722 WP_058502405.1 type IV-A pilus assembly ATPase PilB Machinery gene
  E3983_RS08265 (E3983_08265) pilC 1852047..1853267 (+) 1221 WP_135060608.1 type II secretion system F family protein Machinery gene
  E3983_RS08270 (E3983_08270) - 1853271..1854131 (+) 861 WP_058502286.1 A24 family peptidase -
  E3983_RS08275 (E3983_08275) - 1854357..1854947 (-) 591 WP_058502285.1 hypothetical protein -
  E3983_RS08280 (E3983_08280) - 1854959..1855366 (-) 408 WP_131780737.1 hypothetical protein -
  E3983_RS08285 (E3983_08285) - 1855731..1856546 (+) 816 WP_058502283.1 pyruvate, water dikinase regulatory protein -
  E3983_RS08290 (E3983_08290) - 1856744..1858189 (-) 1446 WP_135060609.1 bifunctional 2-methylcitrate dehydratase/aconitate hydratase -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44585.49 Da        Isoelectric Point: 9.6840

>NTDB_id=352780 E3983_RS08265 WP_135060608.1 1852047..1853267(+) (pilC) [Legionella israelensis strain HL-0427-4011]
MPKNANPMITFQYEGINRSGEKTKGEIEARSLAIAKADLRRQGIITKKVIKKRKSLFDRANKKITQADITVFSRQLATMI
EAGIPLVQSFDIVAKGQSNKRVQDLINTIKNDVETGLTLAESLAKHPAYFNDLFCNLVDAGEKSGSLEVMLNKVATYKEK
IESIKKKIKKALTYPIAVMVIAFLVTAGLLIFVVPQFESLFQGFGADLPAMTRMVIRLSETFQAYWYIIFGVLALAVYAF
IYAKNHSPNFAQGVDRVMLKFPVIGPILEKAAIARFSRTLSITFAAGLPLVDALKSVAGATGNILFAKATDKIREEVSTG
QQMQLAMENTHMFPNMVVQMVAIGEESGALEQMLSKVADFYEEEVDNAVDSLSSLLEPLIMAILGILVGGLVVAMYLPIF
KLGSVV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=352780 E3983_RS08265 WP_135060608.1 1852047..1853267(+) (pilC) [Legionella israelensis strain HL-0427-4011]
ATGCCTAAAAATGCGAATCCAATGATTACCTTTCAATATGAAGGCATCAATCGTTCAGGAGAAAAAACAAAAGGTGAAAT
AGAAGCCAGAAGTCTGGCTATTGCCAAAGCGGATCTTCGCCGACAAGGAATTATTACCAAAAAAGTCATCAAGAAAAGAA
AATCTCTTTTTGACAGAGCCAATAAAAAAATTACTCAGGCTGATATTACCGTTTTCAGTCGGCAGTTGGCCACCATGATA
GAAGCCGGTATTCCTTTGGTACAATCGTTTGATATTGTGGCAAAAGGTCAAAGCAATAAGCGCGTTCAGGATTTAATTAA
TACCATAAAAAATGATGTTGAAACAGGACTTACACTTGCTGAATCATTGGCGAAACATCCGGCTTATTTTAATGATTTAT
TTTGCAACCTGGTCGATGCCGGAGAAAAATCAGGTTCACTGGAGGTCATGTTAAATAAAGTCGCAACTTATAAGGAAAAA
ATAGAATCCATCAAAAAGAAAATTAAAAAAGCGCTGACTTATCCTATAGCCGTTATGGTGATAGCCTTTCTTGTGACCGC
AGGTTTGTTGATTTTTGTCGTTCCTCAGTTTGAGTCTTTATTTCAAGGTTTTGGAGCTGATTTACCGGCCATGACCCGGA
TGGTCATTCGCTTATCTGAGACATTCCAGGCTTATTGGTATATTATTTTCGGTGTTTTAGCACTTGCTGTTTATGCTTTT
ATCTACGCTAAAAATCATTCTCCTAATTTTGCTCAGGGGGTAGATCGCGTCATGCTTAAGTTTCCTGTTATAGGTCCTAT
TCTTGAAAAAGCAGCCATTGCTCGATTTTCACGTACGCTATCCATCACTTTTGCAGCCGGCTTGCCTTTGGTTGATGCTT
TAAAATCAGTTGCCGGAGCCACAGGTAATATTCTTTTTGCCAAGGCGACTGATAAAATCAGAGAAGAAGTCTCGACCGGC
CAACAAATGCAACTCGCCATGGAAAATACTCATATGTTTCCCAATATGGTAGTACAAATGGTAGCGATTGGTGAGGAGTC
GGGCGCTTTGGAGCAAATGCTGTCCAAGGTGGCTGATTTTTATGAAGAAGAAGTGGATAATGCCGTTGATTCATTAAGCA
GTTTACTTGAACCTCTTATTATGGCTATATTAGGCATTCTGGTTGGTGGGCTGGTTGTGGCCATGTATTTACCTATCTTC
AAACTTGGATCAGTGGTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

83.005

100

0.83
  pilC Pseudomonas stutzeri DSM 10701

58.838

97.537

0.574
  pilC Acinetobacter baumannii D1279779

55.309

99.754

0.552
  pilC Acinetobacter baylyi ADP1

54.815

99.754

0.547
  pilG Neisseria meningitidis 44/76-A

44.836

97.783

0.438
  pilG Neisseria gonorrhoeae MS11

44.584

97.783

0.436
  pilC Vibrio cholerae strain A1552

43

98.522

0.424
  pilC Vibrio campbellii strain DS40M4

40.554

97.783

0.397
  pilC Thermus thermophilus HB27

36.973

99.261

0.367

Multiple sequence alignment