Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   HPF_RS19655 Genome accession   NZ_CP037867
Coordinates   4084920..4086137 (+) Length   405 a.a.
NCBI ID   WP_066152952.1    Uniprot ID   A0A1V4CD57
Organism   Hydrogenophaga pseudoflava strain DSM 1084     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4079920..4091137
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPF_RS19630 (HPF_19505) rpmA 4081080..4081337 (-) 258 WP_066152967.1 50S ribosomal protein L27 -
  HPF_RS19635 (HPF_19510) rplU 4081351..4081662 (-) 312 WP_066152961.1 50S ribosomal protein L21 -
  HPF_RS19640 (HPF_19515) - 4081945..4082874 (+) 930 WP_133158174.1 polyprenyl synthetase family protein -
  HPF_RS19650 (HPF_19525) pilB 4083153..4084889 (+) 1737 WP_133157603.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HPF_RS19655 (HPF_19530) pilC 4084920..4086137 (+) 1218 WP_066152952.1 type II secretion system F family protein Machinery gene
  HPF_RS19660 (HPF_19535) pilD 4086143..4086985 (+) 843 WP_133157604.1 A24 family peptidase Machinery gene
  HPF_RS19665 (HPF_19540) coaE 4087000..4087590 (+) 591 WP_133157605.1 dephospho-CoA kinase -
  HPF_RS19670 (HPF_19545) zapD 4087631..4088386 (+) 756 WP_066152938.1 cell division protein ZapD -
  HPF_RS19675 (HPF_19550) - 4088395..4088583 (+) 189 WP_066152933.1 DNA gyrase inhibitor YacG -
  HPF_RS19680 (HPF_19555) - 4088590..4089060 (-) 471 WP_066152930.1 NUDIX domain-containing protein -
  HPF_RS19685 (HPF_19560) - 4089057..4089935 (-) 879 WP_066152927.1 ATP-binding protein -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 44422.19 Da        Isoelectric Point: 9.3633

>NTDB_id=350300 HPF_RS19655 WP_066152952.1 4084920..4086137(+) (pilC) [Hydrogenophaga pseudoflava strain DSM 1084]
MATAASKGTQDFVFEWEGKDRNGKAVRGETRAIGENQVLAAMRRQGIVVTKVKKRRMRSGKRIKPKDIAIFTRQLATMMK
AGVPLLQAFDIVGRGNPNPSLSKLLNDIRSDVETGTSLSAAFRKYPLYFDSLYCNLVEAGEAAGILEELLDRLATYMEKT
EALKSKIKSALMYPVAVIIVAFVVVAVIMIFVIPSFKQVFTSFGADLPGPTLFVIAMSEFFTEYWWLIFGGIFGVSYFFM
QAWKRNEKVQMFMDRLLLKIPIFGALVEKSVIARWTRTLATMFAAGVPLVEALDSVGGASGNSVFSKATERIQQEVSTGT
SLTNAMTNANIFPSMVLQMCAIGEESGSIDHMLGKAADFYEAEVDDMVAGLSSLMEPIIIVVLGTVIGGIVVSMYLPIFK
LGQVV

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=350300 HPF_RS19655 WP_066152952.1 4084920..4086137(+) (pilC) [Hydrogenophaga pseudoflava strain DSM 1084]
ATGGCTACCGCAGCATCAAAAGGCACCCAGGATTTCGTGTTCGAGTGGGAGGGAAAGGATCGCAACGGAAAGGCGGTTCG
GGGCGAGACACGGGCGATTGGAGAAAACCAAGTGCTGGCTGCCATGCGACGCCAAGGCATCGTGGTCACCAAGGTCAAGA
AGCGCCGGATGCGTTCGGGCAAGCGAATCAAGCCCAAGGACATCGCCATCTTCACGCGCCAGTTGGCAACCATGATGAAA
GCAGGCGTCCCCCTCCTGCAGGCTTTCGACATCGTCGGACGTGGCAACCCCAATCCGAGCCTCTCCAAACTGCTCAACGA
CATCCGGTCCGACGTCGAAACCGGTACATCCCTCAGCGCAGCCTTCCGCAAGTATCCGCTGTACTTTGACAGCCTGTACT
GCAATCTCGTCGAAGCGGGGGAAGCGGCCGGCATCTTGGAAGAGTTGCTGGACCGCCTGGCGACCTACATGGAGAAAACG
GAGGCACTGAAGTCGAAGATCAAGTCGGCCCTCATGTACCCGGTCGCGGTGATCATCGTGGCGTTCGTGGTGGTGGCGGT
GATCATGATCTTCGTGATTCCGTCCTTCAAACAGGTGTTCACCTCGTTCGGTGCCGATCTGCCTGGCCCCACACTGTTCG
TGATTGCGATGAGCGAGTTCTTCACCGAATACTGGTGGTTGATCTTCGGCGGCATCTTCGGCGTCTCGTACTTCTTCATG
CAGGCTTGGAAGCGCAATGAAAAAGTGCAAATGTTCATGGACCGACTACTGTTGAAAATACCCATCTTTGGGGCATTGGT
GGAGAAGTCGGTAATCGCACGATGGACCCGCACACTGGCCACCATGTTTGCGGCTGGCGTACCGTTGGTCGAGGCACTGG
ACTCTGTCGGTGGCGCATCGGGCAACTCGGTTTTCTCCAAAGCCACCGAGCGCATCCAGCAGGAGGTATCGACCGGCACC
AGCCTGACCAATGCCATGACCAATGCCAACATCTTCCCTTCCATGGTGCTGCAGATGTGTGCCATCGGTGAAGAATCCGG
CTCCATCGACCACATGCTGGGCAAGGCCGCGGACTTCTACGAGGCCGAAGTGGACGACATGGTCGCTGGGCTGTCCAGCC
TGATGGAACCCATCATCATCGTGGTGCTCGGTACGGTGATCGGTGGCATTGTGGTGTCGATGTACCTGCCAATCTTCAAG
CTGGGCCAGGTCGTTTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(275-397)

Type II secretion system (T2SS), protein F (T2SSF)

(71-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1V4CD57

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

53.713

99.753

0.536
  pilC Acinetobacter baylyi ADP1

50.122

100

0.506
  pilG Neisseria gonorrhoeae MS11

50.75

98.765

0.501
  pilG Neisseria meningitidis 44/76-A

50.25

98.765

0.496
  pilC Legionella pneumophila strain ERS1305867

50.251

98.272

0.494
  pilC Acinetobacter baumannii D1279779

49.875

98.519

0.491
  pilC Vibrio cholerae strain A1552

42.857

98.519

0.422
  pilC Vibrio campbellii strain DS40M4

39.651

99.012

0.393
  pilC Thermus thermophilus HB27

38.75

98.765

0.383

Multiple sequence alignment