Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   ETT57_RS00675 Genome accession   NZ_CP035442
Coordinates   103876..104202 (+) Length   108 a.a.
NCBI ID   WP_053308148.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm25     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98876..109202
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT57_RS00660 (ETT57_00660) - 101508..101873 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT57_RS00665 (ETT57_00665) comYA 101966..102904 (+) 939 WP_009880361.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT57_RS00670 (ETT57_00670) comYB 102840..103874 (+) 1035 WP_227877779.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT57_RS00675 (ETT57_00675) comGC 103876..104202 (+) 327 WP_053308148.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT57_RS00680 (ETT57_00680) comGD 104177..104605 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  ETT57_RS00685 (ETT57_00685) comGE 104562..104846 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  ETT57_RS00690 (ETT57_00690) comYF 104839..105273 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT57_RS00695 (ETT57_00695) comGG 105257..105583 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  ETT57_RS00700 (ETT57_00700) comYH 105681..106634 (+) 954 WP_053308149.1 class I SAM-dependent methyltransferase Machinery gene
  ETT57_RS00705 (ETT57_00705) - 106693..107889 (+) 1197 WP_002987791.1 acetate kinase -
  ETT57_RS00710 (ETT57_00710) - 108075..108383 (+) 309 Protein_90 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12358.33 Da        Isoelectric Point: 9.8992

>NTDB_id=341785 ETT57_RS00675 WP_053308148.1 103876..104202(+) (comGC) [Streptococcus pyogenes strain emm25]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLILLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=341785 ETT57_RS00675 WP_053308148.1 103876..104202(+) (comGC) [Streptococcus pyogenes strain emm25]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATACTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Lactococcus lactis subsp. cremoris KW2

57.843

94.444

0.546
  comYC Streptococcus gordonii str. Challis substr. CH1

55.238

97.222

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment