Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   ETT62_RS00660 Genome accession   NZ_CP035437
Coordinates   101990..102928 (+) Length   312 a.a.
NCBI ID   WP_136121098.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm78.3     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 96990..107928
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT62_RS00650 (ETT62_00650) rpoC 97739..101380 (+) 3642 WP_136121099.1 DNA-directed RNA polymerase subunit beta' -
  ETT62_RS00655 (ETT62_00655) - 101532..101897 (+) 366 WP_002986560.1 DUF1033 family protein -
  ETT62_RS00660 (ETT62_00660) comYA 101990..102928 (+) 939 WP_136121098.1 competence type IV pilus ATPase ComGA Machinery gene
  ETT62_RS00665 (ETT62_00665) comYB 102864..103898 (+) 1035 WP_227878200.1 competence type IV pilus assembly protein ComGB Machinery gene
  ETT62_RS00670 (ETT62_00670) comYC 103900..104226 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  ETT62_RS00675 (ETT62_00675) comGD 104201..104629 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  ETT62_RS00680 (ETT62_00680) comGE 104586..104870 (+) 285 WP_011284422.1 competence type IV pilus minor pilin ComGE -
  ETT62_RS00685 (ETT62_00685) comYF 104863..105297 (+) 435 WP_002992738.1 competence type IV pilus minor pilin ComGF Machinery gene
  ETT62_RS00690 (ETT62_00690) comGG 105281..105607 (+) 327 WP_009880358.1 competence type IV pilus minor pilin ComGG -
  ETT62_RS00695 (ETT62_00695) comYH 105705..106658 (+) 954 WP_136121096.1 class I SAM-dependent methyltransferase Machinery gene
  ETT62_RS00700 (ETT62_00700) - 106717..107913 (+) 1197 WP_136121095.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35004.22 Da        Isoelectric Point: 8.2452

>NTDB_id=341514 ETT62_RS00660 WP_136121098.1 101990..102928(+) (comYA) [Streptococcus pyogenes strain emm78.3]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDQMAPLISHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISSYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHRPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide


Download         Length: 939 bp        

>NTDB_id=341514 ETT62_RS00660 WP_136121098.1 101990..102928(+) (comYA) [Streptococcus pyogenes strain emm78.3]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCAGATGGCTCCTC
TTATTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTTAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAGTTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCGACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

61.736

99.679

0.615
  comYA Streptococcus mutans UA140

61.736

99.679

0.615
  comYA Streptococcus gordonii str. Challis substr. CH1

61.093

99.679

0.609
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

60.968

99.359

0.606
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

59.807

99.679

0.596
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae D39

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae R6

59.164

99.679

0.59
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

59.164

99.679

0.59
  comGA Lactococcus lactis subsp. cremoris KW2

50.482

99.679

0.503
  comGA Latilactobacillus sakei subsp. sakei 23K

39.655

92.949

0.369

Multiple sequence alignment