Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   F1537_RS05500 Genome accession   NZ_CP043770
Coordinates   1053219..1055048 (+) Length   609 a.a.
NCBI ID   WP_013525416.1    Uniprot ID   -
Organism   Haemophilus influenzae biotype aegyptius strain HE7/F1946     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1048219..1060048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  F1537_RS05485 (F1537_05495) msbA 1049413..1051176 (+) 1764 WP_005663238.1 lipid A ABC transporter ATP-binding protein/permease MsbA -
  F1537_RS05490 (F1537_05500) lpxK 1051249..1052247 (+) 999 WP_013525418.1 tetraacyldisaccharide 4'-kinase -
  F1537_RS05495 (F1537_05505) kdsB 1052318..1053082 (+) 765 WP_013525417.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  F1537_RS05500 (F1537_05510) uvrC 1053219..1055048 (+) 1830 WP_013525416.1 excinuclease ABC subunit UvrC Machinery gene
  F1537_RS05505 (F1537_05515) - 1055146..1055859 (+) 714 WP_013525415.1 TerC family protein -
  F1537_RS05510 (F1537_05520) - 1055874..1056224 (-) 351 WP_013525414.1 zinc ribbon domain-containing protein YjdM -
  F1537_RS05515 (F1537_05525) - 1056328..1056882 (+) 555 WP_013525413.1 YtfJ family protein -
  F1537_RS05525 (F1537_05535) - 1057209..1057871 (+) 663 WP_005649826.1 Bax inhibitor-1/YccA family protein -
  F1537_RS05530 (F1537_05540) - 1057931..1058995 (+) 1065 WP_013525412.1 YcjF family protein -
  F1537_RS05535 (F1537_05545) - 1058995..1059669 (+) 675 WP_013525411.1 TIGR01621 family pseudouridine synthase -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69515.43 Da        Isoelectric Point: 9.5182

>NTDB_id=338576 F1537_RS05500 WP_013525416.1 1053219..1055048(+) (uvrC) [Haemophilus influenzae biotype aegyptius strain HE7/F1946]
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTMLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQQVLDYLIGKMEQASRNLGFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLSEQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQFKQSSRMSARYQALCDLLNLPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERNLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVARRAGQEVLIISKQDREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISPKLAERIFETLKND

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=338576 F1537_RS05500 WP_013525416.1 1053219..1055048(+) (uvrC) [Haemophilus influenzae biotype aegyptius strain HE7/F1946]
ATGTTCAATTACAAAAAATTCCTCGCTGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGACGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATCTAAAAAAACGTCTTTCAAGCTATTTTCGTAAAAATCTGAGTAGTAAAAAAACAG
AGGCGTTGGTGGCATCAATTCATCATATTGACACCATGCTAACTTCATCTGAAACGGAAGCTTTACTGCTAGAGCATAAT
TTTATCAAGCTTTATCAGCCTCGCTATAACGTATTATTGCGTGATGATAAATCCTATCCATTTATTTTATTAACCAAAGA
ACGTCATCCAAGAATCACGTCTTATCGTGGGTCTAAAAAATTTGCGGGTGAATATTTCGGGCCTTATCCTCACGCGGGAG
CCGTGCGTGAAACTTTATCGCTTTTGCAAAAACTTTTCCCTGTTCGACAATGTGAAAATTCCGTTTATTCCAACCGCTCT
CGTCCTTGTTTGCAGTATCAAATTGGGCGTTGTTCTGCGCCTTGTGTACAGGGATATGTTTCCGATGAAGAATATAATCA
GCAAGTTGAATTAGCGCGTTTATTTTTACAAGGCAAAGATCAACAGGTGTTAGATTATTTAATCGGTAAAATGGAGCAGG
CAAGCAGAAATTTAGGTTTTGAACAGGCTGCTCGTTATCGCGATCAAATTCAGGCGGTGCGTTCGGTTATAGAGAAACAA
TTTGTATCTAATGAGCGTTTAGATGATATGGATATTATGTCTATCGCTTACCAACACGGGTTAGCCTGTGTACAGGTTAT
GTTTATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTATTTCCCAAAAGTCCCCGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTGGGGCAATTTTATTTACAAGGTCATCAAGGACGAAGTATCCCGAATAGCATTATTGTTGATCGTCAA
TTAGCTGAAAAATCAGAGCTTGAGCAACTTCTTAGCGAGCAAGCGGGCAGAAAAGTAACGATTCAAGAAAGCGTAAAAGG
CGATAAGAGTAAATACTTACAGCTCGCACAAGTTAATGCTAAAGCGGCTTTAAATGTACAATTTAAACAATCTTCACGAA
TGTCAGCGCGTTATCAAGCGTTATGTGATCTGTTAAATCTTCCTGAAATTAAGCGTATGGAATGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACAGTAGCATCTTGCGTTGTCTTTAATCAAGAAGGACCACTGAAATCTGATTATCGCCGTTTTAA
TATTGAAGGCATTACTGGCGGGGATGATTATGCAGCGATGGAACAAGCCCTGCAGAAACGTTACGAACGTAATTTAGAAG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGAAAAGGGCAGTTAAATCGTGCGCTGAACGTGTTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGGGTTGCTCGTCGAGCAGGGCAGGAAGTGCT
GATTATCAGCAAACAAGACCGCGAAATTCATTTGCCCGATGATAGTTTGGCATTGCATTTGATTCAACATATCCGTGATG
AAAGCCATAATCACGCCATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGTGGTTTAGAAACCATTGAA
GGCGTGGGTGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGTGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCGGGCATTTCCCCTAAACTTGCTGAAAGGATTTTTGAAACGCTTAAAAACGACTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrB/uvrC motif (UVR)

(210-234)

Helix-hairpin-helix domain (HHH_5)

(556-607)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.355

99.343

0.371
  uvrC Streptococcus pneumoniae R6

37.025

99.343

0.368
  uvrC Streptococcus pneumoniae D39

37.025

99.343

0.368

Multiple sequence alignment