Detailed information NTG0338165

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EQH22_RS08560
• Genome accession: NZ_CP035258
• Coordinates: 1714274..1715341 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1901927
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1709274..1720341

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH22_RS08535 (EQH22_08995)	treR	1709445..1710155 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
EQH22_RS08540 (EQH22_09000)	-	1710188..1710991 (-)	804	WP_000157664.1	ABC transporter ATP-binding protein	-
EQH22_RS08545 (EQH22_09005)	-	1711004..1711897 (-)	894	WP_001012093.1	ABC transporter permease	-
EQH22_RS08550 (EQH22_09010)	-	1711909..1712718 (-)	810	Protein_1720	ABC transporter substrate-binding protein	-
EQH22_RS08555 (EQH22_09015)	amiF	1713337..1714263 (-)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
EQH22_RS08560 (EQH22_09020)	amiE	1714274..1715341 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
EQH22_RS08565 (EQH22_09025)	amiD	1715350..1716276 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
EQH22_RS08570 (EQH22_09030)	amiC	1716276..1717772 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
EQH22_RS08575 (EQH22_09035)	amiA3	1717839..1719818 (-)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=338165 EQH22_RS08560 WP_000159554.1 1714274..1715341(-) (amiE) [Streptococcus pneumoniae strain TVO_1901927]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=338165 EQH22_RS08560 WP_000159554.1 1714274..1715341(-) (amiE) [Streptococcus pneumoniae strain TVO_1901927]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAAATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541