Detailed information NTG0338077

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: FTN78_RS12000
• Genome accession: NZ_CP043523
• Coordinates: 2325187..2325852 (-)
• Length: 221 a.a.
• NCBI ID: WP_004254535.1
• Uniprot ID: Q9CE22
• Organism: Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2320187..2330852

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FTN78_RS11980 (FTN78_chr2399)	-	2320681..2321811 (+)	1131	WP_010906275.1	aminotransferase	-
FTN78_RS11985 (FTN78_chr2400)	-	2322003..2323496 (+)	1494	WP_150891151.1	basic amino acid/polyamine antiporter	-
FTN78_RS11990 (FTN78_chr2401)	-	2323575..2324066 (+)	492	WP_010906273.1	prolyl-tRNA synthetase associated domain-containing protein	-
FTN78_RS11995 (FTN78_chr2402)	dinB	2324145..2325236 (+)	1092	WP_010906272.1	DNA polymerase IV	-
FTN78_RS12000 (FTN78_chr2403)	cclA/cilC	2325187..2325852 (-)	666	WP_004254535.1	A24 family peptidase	Machinery gene
FTN78_RS12005 (FTN78_chr2404)	-	2326019..2326465 (+)	447	WP_004254538.1	DNA starvation/stationary phase protection protein	-
FTN78_RS12010 (FTN78_chr2405)	-	2326548..2326934 (-)	387	WP_010906271.1	rhodanese-like domain-containing protein	-
FTN78_RS12015 (FTN78_chr2406)	-	2326937..2327908 (-)	972	WP_004254542.1	ROK family glucokinase	-
FTN78_RS12020 (FTN78_chr2407)	-	2327942..2328163 (-)	222	WP_010906270.1	YqgQ family protein	-
FTN78_RS12025 (FTN78_chr2408)	-	2328356..2329084 (+)	729	WP_004254546.1	LytTR family transcriptional regulator DNA-binding domain-containing protein	-
FTN78_RS12030 (FTN78_chr2409)	-	2329384..2329710 (+)	327	WP_010906269.1	lactococcin 972 family bacteriocin	-

Sequence

Protein

• Length: 221 a.a.
• Molecular weight: 25664.87 Da
• Isoelectric Point: 8.8481

>NTDB_id=338077 FTN78_RS12000 WP_004254535.1 2325187..2325852(-) (cclA/cilC) [Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96]
MDILFIFLIGSIFGSFFGLIVDRIPLRKSIIFGRSHCDSCQQLLAYRDLIPIFSQISSGSHCRYCKSKIPYLYVFLEFSS
ALIFVLAWVNYLKPSQFLLIILSLILSAFDYRQHSFPFVIWFIFALSFILIFPLSPLFYFWLILAVLAEKFNLRVGSGDF
LWFFTASFSLTFLNEMLLLQIACSLGIIYYLITKKRVEIAFIPFLTIAYLMLLFGHQILSP

Nucleotide

• Length: 666 bp

>NTDB_id=338077 FTN78_RS12000 WP_004254535.1 2325187..2325852(-) (cclA/cilC) [Lactococcus lactis subsp. lactis bv. diacetylactis strain SD96]
ATGGACATTTTATTTATATTTTTAATTGGAAGTATTTTTGGCTCCTTTTTTGGCTTAATAGTTGACCGTATTCCACTAAG
AAAATCAATTATTTTTGGACGCTCACATTGTGATTCTTGTCAGCAACTTTTAGCCTATCGTGATCTAATTCCTATTTTTT
CTCAAATAAGCTCTGGCTCACATTGCCGTTATTGTAAAAGTAAAATTCCATATTTATATGTTTTTTTGGAGTTCTCATCA
GCTTTAATTTTTGTTTTAGCTTGGGTAAATTATCTTAAACCTAGTCAATTTTTACTGATTATTCTTTCACTAATTTTATC
TGCTTTTGATTATCGTCAGCACAGTTTTCCTTTTGTTATCTGGTTTATTTTTGCACTCAGTTTTATTTTAATATTTCCTC
TTTCTCCCCTTTTCTATTTTTGGCTTATTTTAGCCGTCTTAGCTGAAAAATTCAATTTAAGAGTTGGCAGCGGTGATTTT
TTATGGTTTTTTACCGCTTCATTTTCTCTAACTTTCTTAAACGAAATGCTGCTCCTTCAAATCGCTTGTTCACTTGGTAT
CATTTATTATCTAATCACAAAAAAACGAGTTGAAATTGCCTTCATCCCGTTTCTAACTATTGCATATCTAATGTTGCTTT
TTGGGCACCAAATTCTGTCACCGTAA

Domains

Predicted by InterProScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-90)

3D structure

• AlphaFold DB: Q9CE22

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus mitis SK321	37.9	99.095	0.376
cclA/cilC	Streptococcus pneumoniae Rx1	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae D39	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae R6	38.14	97.285	0.371
cclA/cilC	Streptococcus pneumoniae TIGR4	37.674	97.285	0.367