Detailed information NTG0337131

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: EQH38_RS03100
• Genome accession: NZ_CP035242
• Coordinates: 547016..548083 (+)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1901947
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 542016..553083

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH38_RS03085 (EQH38_03240)	amiA3	542539..544518 (+)	1980	WP_000742234.1	peptide ABC transporter substrate-binding protein	Regulator
EQH38_RS03090 (EQH38_03245)	amiC	544585..546081 (+)	1497	WP_000759901.1	ABC transporter permease	Regulator
EQH38_RS03095 (EQH38_03250)	amiD	546081..547007 (+)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
EQH38_RS03100 (EQH38_03255)	amiE	547016..548083 (+)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
EQH38_RS03105 (EQH38_03260)	amiF	548094..549020 (+)	927	WP_001291293.1	ATP-binding cassette domain-containing protein	Regulator
EQH38_RS03110	-	549640..550449 (+)	810	Protein_576	ABC transporter substrate-binding protein	-
EQH38_RS03115 (EQH38_03275)	-	550461..551338 (+)	878	Protein_577	ABC transporter permease	-
EQH38_RS03120 (EQH38_03280)	-	551351..552154 (+)	804	WP_238097320.1	ABC transporter ATP-binding protein	-
EQH38_RS03125 (EQH38_03285)	treR	552187..552896 (-)	710	Protein_579	trehalose operon repressor	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=337131 EQH38_RS03100 WP_000159554.1 547016..548083(+) (amiE) [Streptococcus pneumoniae strain TVO_1901947]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=337131 EQH38_RS03100 WP_000159554.1 547016..548083(+) (amiE) [Streptococcus pneumoniae strain TVO_1901947]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTCGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCGAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541