Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SP70585_RS10035 Genome accession   NC_012468
Coordinates   1857523..1858779 (-) Length   418 a.a.
NCBI ID   WP_000642705.1    Uniprot ID   A0A0T7I3F9
Organism   Streptococcus pneumoniae 70585     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1852523..1863779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS10010 - 1852580..1852786 (-) 207 WP_000366087.1 hypothetical protein -
  SP70585_RS10015 (SP70585_2015) - 1852773..1852934 (-) 162 WP_000289348.1 helix-turn-helix domain-containing protein -
  SP70585_RS10020 (SP70585_2016) lytA 1853293..1854249 (-) 957 WP_000405234.1 N-acetylmuramoyl-L-alanine amidase LytA -
  SP70585_RS10025 (SP70585_2018) - 1854625..1855995 (-) 1371 WP_001036282.1 MATE family efflux transporter -
  SP70585_RS10030 (SP70585_2019) recA 1856302..1857468 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  SP70585_RS10035 (SP70585_2020) cinA 1857523..1858779 (-) 1257 WP_000642705.1 competence/damage-inducible protein A Machinery gene
  SP70585_RS10040 (SP70585_2021) brpA 1858864..1859880 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  SP70585_RS10045 (SP70585_2022) - 1859888..1860406 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  SP70585_RS10050 (SP70585_2023) tsaE 1860396..1860839 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  SP70585_RS10055 (SP70585_2024) comM 1860926..1861546 (-) 621 WP_000839908.1 hypothetical protein Regulator
  SP70585_RS10060 (SP70585_2025) - 1861929..1862792 (-) 864 WP_001093623.1 helix-turn-helix domain-containing protein -
  SP70585_RS14185 (SP70585_2026) - 1862981..1863151 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45047.43 Da        Isoelectric Point: 4.6064

>NTDB_id=33330 SP70585_RS10035 WP_000642705.1 1857523..1858779(-) (cinA) [Streptococcus pneumoniae 70585]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGASSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=33330 SP70585_RS10035 WP_000642705.1 1857523..1858779(-) (cinA) [Streptococcus pneumoniae 70585]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGGCAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCAACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGTTGGTTACGATTTTGGCTGATTTAATTGATAATCAGATCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAGCTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACCGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGAGCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CATATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-414)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T7I3F9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.282

100

0.993
  cinA Streptococcus pneumoniae Rx1

99.043

100

0.99
  cinA Streptococcus pneumoniae R6

99.043

100

0.99
  cinA Streptococcus pneumoniae D39

98.804

100

0.988
  cinA Streptococcus mitis SK321

94.258

100

0.943
  cinA Streptococcus mitis NCTC 12261

94.019

100

0.94
  cinA Streptococcus mutans UA159

71.292

100

0.713
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment