Detailed information    

insolico Bioinformatically predicted

Overview

Name   comM   Type   Regulator
Locus tag   SP70585_RS10055 Genome accession   NC_012468
Coordinates   1860926..1861546 (-) Length   206 a.a.
NCBI ID   WP_000839908.1    Uniprot ID   A0A0B7M636
Organism   Streptococcus pneumoniae 70585     
Function   fratricide immunity (predicted from homology)   
Competence regulation

Genomic Context

Location: 1855926..1866546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS10030 (SP70585_2019) recA 1856302..1857468 (-) 1167 WP_001085463.1 recombinase RecA Machinery gene
  SP70585_RS10035 (SP70585_2020) cinA 1857523..1858779 (-) 1257 WP_000642705.1 competence/damage-inducible protein A Machinery gene
  SP70585_RS10040 (SP70585_2021) brpA 1858864..1859880 (-) 1017 WP_000239282.1 biofilm formation/cell division transcriptional regulator BrpA -
  SP70585_RS10045 (SP70585_2022) - 1859888..1860406 (-) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  SP70585_RS10050 (SP70585_2023) tsaE 1860396..1860839 (-) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  SP70585_RS10055 (SP70585_2024) comM 1860926..1861546 (-) 621 WP_000839908.1 hypothetical protein Regulator
  SP70585_RS10060 (SP70585_2025) - 1861929..1862792 (-) 864 WP_001093623.1 helix-turn-helix domain-containing protein -
  SP70585_RS14185 (SP70585_2026) - 1862981..1863151 (+) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  SP70585_RS10070 (SP70585_2027) - 1863296..1865311 (+) 2016 WP_000732371.1 DUF1430 domain-containing protein -
  SP70585_RS10075 (SP70585_2028) - 1865313..1865945 (+) 633 WP_000571415.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 23552.72 Da        Isoelectric Point: 10.1254

>NTDB_id=33331 SP70585_RS10055 WP_000839908.1 1860926..1861546(-) (comM) [Streptococcus pneumoniae 70585]
MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFVSGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLL
INLLGAVLVLSDNLFIKNTLQQELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF

Nucleotide


Download         Length: 621 bp        

>NTDB_id=33331 SP70585_RS10055 WP_000839908.1 1860926..1861546(-) (comM) [Streptococcus pneumoniae 70585]
ATGAAATCAATGAGAATCTTATTTTTGTTAGCTTTAATTCAAATCAGTTTGAGTAGCTGTTTCCTATGGAAGGAATGCAT
CTTGTCCTTTAAACAAAGTACAGCTTTTTTCATCGGAAGCATGGTTTTCGTTTCAGGAATCTGTGCTGGAGTAAATTATC
TTTATACCCGTAAGCAAGAAGTCCATAGTGTCCTAGCCAGTAAGAAGTCGGTGAAGCTTTTTTACAGTATGTTACTCTTA
ATTAATTTGTTAGGAGCTGTTCTTGTTTTGTCAGATAACTTGTTCATCAAAAATACGCTGCAGCAAGAATTAGTTGACTT
TTTATTGCCATCCTTCTTTTTCCTATTTGGGCTAGATTTGCTGATTTTTTTACCCTTGAAAAAATACGTGCGCGATTTTC
TTGCTATGCTAGACAGAAAAAAGACAGTGTTGGTGACTATTTTAGCAACACTTCTTTTCTTAAGAAATCCAATGACCATT
GTCTCACTTCTGATTTATATTGGACTGGGCTTGTTTTTTGCAGCCTATCTTGTCCCAAATTCGGTTAAGAAGGAAGTTTC
CTTTTATGGTCATATTTTCCGAGATCTTGTATTGGTCATTGTTACGCTCATTTTCTTTTAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M636

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comM Streptococcus pneumoniae D39

100

100

1
  comM Streptococcus pneumoniae R6

100

100

1
  comM Streptococcus pneumoniae TIGR4

100

100

1
  comM Streptococcus mitis NCTC 12261

38.974

94.66

0.369
  comM Streptococcus mitis SK321

38.974

94.66

0.369

Multiple sequence alignment