Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EHW89_RS08760 Genome accession   NZ_CP034543
Coordinates   1788196..1789464 (-) Length   422 a.a.
NCBI ID   WP_126467892.1    Uniprot ID   A0A3Q9F4R2
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1783196..1794464
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS08725 (EHW89_08725) - 1783908..1784219 (-) 312 WP_003027765.1 DUF1292 domain-containing protein -
  EHW89_RS08730 (EHW89_08730) ruvX 1784237..1784656 (-) 420 WP_003026628.1 Holliday junction resolvase RuvX -
  EHW89_RS08735 (EHW89_08735) - 1784656..1784922 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  EHW89_RS08740 (EHW89_08740) - 1785203..1785760 (-) 558 WP_003026633.1 SP0191 family lipoprotein -
  EHW89_RS08745 (EHW89_08745) - 1785864..1786433 (-) 570 WP_003026634.1 SP0191 family lipoprotein -
  EHW89_RS08750 (EHW89_08750) spx 1786519..1786917 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  EHW89_RS08755 (EHW89_08755) recA 1787004..1788149 (-) 1146 WP_126467890.1 recombinase RecA Machinery gene
  EHW89_RS08760 (EHW89_08760) cinA 1788196..1789464 (-) 1269 WP_126467892.1 competence/damage-inducible protein A Machinery gene
  EHW89_RS08770 (EHW89_08770) - 1790065..1790478 (+) 414 WP_193552992.1 EamA family transporter -
  EHW89_RS08775 (EHW89_08775) - 1790581..1791159 (-) 579 WP_049517293.1 DNA-3-methyladenine glycosylase I -
  EHW89_RS08780 (EHW89_08780) ruvA 1791170..1791760 (-) 591 WP_126467896.1 Holliday junction branch migration protein RuvA -
  EHW89_RS08785 (EHW89_08785) - 1791922..1792431 (+) 510 WP_126467898.1 helix-turn-helix domain-containing protein -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45798.47 Da        Isoelectric Point: 8.2838

>NTDB_id=331804 EHW89_RS08760 WP_126467892.1 1788196..1789464(-) (cinA) [Streptococcus periodonticum strain KCOM 2412]
MKAEIIAVGTEILTGQIVNTNARFLSEKLASLGVDVYFQTAVGDNEARLLSILEIARNRSNLVILTGGLGPTEDDLTKQT
LAKFLNRRLVFDRMATEKLDRFFASRPNYARTPNNERQAQIVGGSTPLQNETGLAVGGVIEVSGVTYVVLPGPPSELKPM
VNNKLVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDNQTDPTIAPYAKTGEVTLRLSTKATSQKEADIKFAHLEKKI
LAVQTFEKQHLVDLFYAYGDDNSLGQTAFELLRRAEKTVTAAESLTAGLFQATLANFSGASNVFSGGFVTYSMEEKSRML
SIPLADLEKHGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTEDVQSIKVNIAGRSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=331804 EHW89_RS08760 WP_126467892.1 1788196..1789464(-) (cinA) [Streptococcus periodonticum strain KCOM 2412]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAGATTGTCAATACAAATGCCCGATTTTTATCGGA
AAAATTAGCGAGTCTGGGTGTAGATGTATATTTCCAAACAGCAGTTGGAGATAATGAAGCTCGTCTGTTATCCATTTTAG
AAATTGCTCGAAATCGTAGTAATTTGGTCATCTTAACTGGAGGATTAGGCCCAACAGAAGATGACTTGACTAAGCAGACT
TTGGCAAAATTCTTAAATCGTAGGTTGGTATTTGACCGAATGGCTACGGAGAAATTGGACCGCTTTTTCGCAAGTCGACC
GAATTATGCTCGAACACCAAACAATGAGCGACAAGCTCAGATAGTGGGAGGCTCGACTCCTCTACAAAATGAAACTGGGC
TTGCAGTAGGAGGCGTGATTGAGGTCAGTGGCGTGACCTATGTTGTTCTACCTGGTCCGCCTAGTGAATTAAAACCTATG
GTGAACAATAAGCTGGTTCCACTTTTAGCGACTGGTCAAAAATTGTATTCAAGAGTCTTACGTTTCTTTGGTATCGGTGA
AAGTCAATTAGTAACCCTTTTAGGAGATTTAATTGATAATCAGACCGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACCAAGGCTACTAGTCAAAAGGAAGCAGATATTAAGTTTGCTCATTTAGAAAAGAAAATT
TTAGCAGTACAGACTTTTGAGAAACAACATTTAGTAGACCTTTTCTACGCTTATGGAGATGATAATTCTCTGGGGCAAAC
AGCTTTTGAACTGCTGAGAAGAGCAGAAAAGACCGTCACAGCAGCTGAAAGTTTGACCGCAGGACTCTTTCAAGCGACTT
TGGCAAACTTTTCTGGAGCCTCCAATGTCTTTAGTGGTGGCTTTGTTACCTACAGTATGGAGGAAAAGAGCCGAATGCTG
AGCATTCCCTTGGCAGACTTAGAAAAGCATGGGGTAGTTTCAGCTTTTACAGCGGAGAAAATGGCTGAGCAGGCAAGAAA
ATTGACCGCTAGTGACTATGCGGTGAGCTTGACAGGTGTGGCAGGTCCAGACAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATCGGCCTAGCAACCACAGAAGATGTTCAGTCTATTAAGGTTAATATTGCGGGTCGCAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATCTGCTGCGAAAAACTTTATTAAAAAACGAAAACATGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q9F4R2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

76.316

99.052

0.756
  cinA Streptococcus mitis NCTC 12261

75.359

99.052

0.746
  cinA Streptococcus pneumoniae TIGR4

75.12

99.052

0.744
  cinA Streptococcus pneumoniae Rx1

75.12

99.052

0.744
  cinA Streptococcus pneumoniae R6

75.12

99.052

0.744
  cinA Streptococcus pneumoniae D39

74.88

99.052

0.742
  cinA Streptococcus mutans UA159

71.631

100

0.718
  cinA Streptococcus suis isolate S10

55.529

98.578

0.547
  cinA Bacillus subtilis subsp. subtilis str. 168

44.976

99.052

0.445

Multiple sequence alignment