Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SUB_RS08840 Genome accession   NC_012004
Coordinates   1765432..1766703 (-) Length   423 a.a.
NCBI ID   WP_015912069.1    Uniprot ID   B9DW66
Organism   Streptococcus uberis 0140J     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1760432..1771703
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS08810 (SUB1773) - 1760662..1762224 (-) 1563 WP_015912064.1 membrane protein -
  SUB_RS08815 (SUB1774) - 1762380..1762685 (-) 306 WP_015912065.1 DUF1292 domain-containing protein -
  SUB_RS08820 (SUB1775) ruvX 1762696..1763115 (-) 420 WP_015912066.1 Holliday junction resolvase RuvX -
  SUB_RS08825 (SUB1776) - 1763112..1763381 (-) 270 WP_003083367.1 IreB family regulatory phosphoprotein -
  SUB_RS08830 (SUB1777) spx 1763497..1763895 (-) 399 WP_015912067.1 transcriptional regulator Spx -
  SUB_RS08835 (SUB1778) recA 1764211..1765350 (-) 1140 WP_015912068.1 recombinase RecA Machinery gene
  SUB_RS08840 (SUB1779) cinA 1765432..1766703 (-) 1272 WP_015912069.1 competence/damage-inducible protein A Machinery gene
  SUB_RS08845 (SUB1780) - 1766794..1767348 (-) 555 WP_015912070.1 DNA-3-methyladenine glycosylase I -
  SUB_RS08850 (SUB1781) ruvA 1767353..1767946 (-) 594 WP_015912071.1 Holliday junction branch migration protein RuvA -
  SUB_RS08855 (SUB1782) - 1767948..1769171 (-) 1224 WP_015912072.1 MDR family MFS transporter -
  SUB_RS08860 (SUB1783) mutL 1769181..1771163 (-) 1983 WP_015912073.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45552.19 Da        Isoelectric Point: 6.1834

>NTDB_id=32949 SUB_RS08840 WP_015912069.1 1765432..1766703(-) (cinA) [Streptococcus uberis 0140J]
MKAEIIAVGTELLTGQVLNTNAQFLSEKMAEIGVDVFFQTAVGDNESRLLNLLDIASQRSDLILLCGGLGPTEDDLTKQT
VASFLGKSLVFEPSASQKLDHFFASRPHYSRTPNNERQAQIIEGSTPIPNITGLAVGGILEVDGVTYVLLPGPPSELKPM
VNQYLLPALSGNHTALYSRVLRFFGIGESQLVTILSEMIHKQSDPTIAPYAKIGEVTLRLSTKAETPEQAKAKLDGLEQK
ILQTPSFEGGLLADYHYGYGETNSLSAEVVNMLKERSMTITAAESLTAGLFQSTIADFPGSSKLFRGGFVTYHIEEKAKM
LQLQLSDLELHGVVSAFTAKKMAEQSRHLTASDIGVGLTGVAGPDALEGHNVGTVFIGIATLKGAKSYKVSIGGRSRSDI
RYIACLHAFDLVRKTLLNGLNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=32949 SUB_RS08840 WP_015912069.1 1765432..1766703(-) (cinA) [Streptococcus uberis 0140J]
ATGAAAGCTGAAATAATAGCAGTTGGAACAGAATTGTTAACAGGACAAGTTTTAAATACGAATGCGCAATTTTTATCTGA
AAAAATGGCTGAGATTGGAGTTGATGTTTTTTTTCAAACAGCTGTGGGTGATAATGAATCTCGCTTACTAAACTTACTTG
ACATTGCAAGCCAGAGAAGTGATTTAATCCTTCTATGTGGAGGTTTAGGTCCAACAGAGGATGATTTAACAAAACAAACT
GTTGCAAGCTTTTTAGGGAAGTCTTTAGTTTTTGAGCCATCCGCCAGTCAAAAATTAGATCACTTTTTTGCGAGTCGACC
TCATTATTCCCGAACTCCAAATAATGAGCGACAAGCGCAAATTATTGAGGGGTCAACACCCATCCCAAATATTACAGGAC
TGGCTGTTGGTGGTATTTTGGAAGTTGATGGTGTAACCTATGTTCTTTTACCAGGACCACCAAGTGAATTAAAACCGATG
GTCAACCAATACCTTCTACCAGCATTATCAGGTAATCATACTGCCTTATACTCAAGAGTATTGCGTTTTTTCGGCATTGG
AGAAAGTCAACTTGTGACAATTTTATCAGAAATGATTCATAAGCAATCAGACCCAACAATTGCACCTTATGCAAAGATTG
GTGAAGTGACATTGCGGTTGTCAACAAAAGCAGAAACACCTGAGCAGGCAAAAGCAAAGCTAGATGGTCTTGAACAGAAA
ATTTTACAAACGCCTAGCTTTGAAGGTGGATTATTAGCAGACTATCATTATGGTTATGGCGAAACCAATAGTCTCAGTGC
AGAAGTCGTAAACATGTTAAAGGAAAGAAGCATGACAATAACAGCTGCAGAGAGTCTAACCGCTGGGCTTTTTCAATCAA
CAATTGCCGACTTTCCAGGATCTTCTAAACTATTTCGTGGCGGTTTTGTGACATACCATATTGAGGAAAAGGCTAAAATG
TTACAGTTACAGCTAAGTGATTTAGAGCTCCATGGAGTTGTAAGTGCGTTTACGGCTAAAAAAATGGCGGAGCAGTCACG
TCATTTAACAGCAAGTGATATTGGAGTTGGACTAACAGGTGTGGCAGGACCAGATGCTTTAGAAGGACATAATGTGGGAA
CAGTGTTTATTGGAATTGCAACCTTAAAAGGAGCAAAATCATATAAAGTATCAATAGGTGGAAGAAGTCGTTCAGACATC
CGGTATATTGCTTGTTTACACGCTTTTGATTTGGTCCGAAAAACTTTATTAAATGGTTTGAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-242)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DW66

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.292

98.818

0.704
  cinA Streptococcus mitis NCTC 12261

69.856

98.818

0.69
  cinA Streptococcus pneumoniae Rx1

69.617

98.818

0.688
  cinA Streptococcus pneumoniae TIGR4

69.617

98.818

0.688
  cinA Streptococcus pneumoniae R6

69.617

98.818

0.688
  cinA Streptococcus pneumoniae D39

69.378

98.818

0.686
  cinA Streptococcus mutans UA159

67.849

100

0.678
  cinA Streptococcus suis isolate S10

52.644

98.345

0.518
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

98.818

0.456

Multiple sequence alignment