Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   EGX82_RS04930 Genome accession   NZ_CP033822
Coordinates   936668..937639 (-) Length   323 a.a.
NCBI ID   WP_025197279.1    Uniprot ID   A0AAW6XWD3
Organism   Streptococcus agalactiae strain FDAARGOS_512     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 931668..942639
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX82_RS04895 (EGX82_04895) - 931957..933150 (-) 1194 WP_000047535.1 acetate kinase -
  EGX82_RS04900 (EGX82_04900) comYH 933182..934156 (-) 975 WP_001008570.1 class I SAM-dependent methyltransferase Machinery gene
  EGX82_RS04905 (EGX82_04905) comGG 934271..934642 (-) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG -
  EGX82_RS04910 (EGX82_04910) comGF 934620..935081 (-) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  EGX82_RS04915 (EGX82_04915) comGE 935035..935334 (-) 300 WP_001867089.1 competence type IV pilus minor pilin ComGE -
  EGX82_RS04920 (EGX82_04920) comYD 935306..935734 (-) 429 WP_000793381.1 competence type IV pilus minor pilin ComGD Machinery gene
  EGX82_RS04925 (EGX82_04925) comYB 935731..936774 (-) 1044 WP_223295592.1 competence type IV pilus assembly protein ComGB Machinery gene
  EGX82_RS04930 (EGX82_04930) comYA 936668..937639 (-) 972 WP_025197279.1 competence type IV pilus ATPase ComGA Machinery gene
  EGX82_RS04940 (EGX82_04940) - 937812..938177 (-) 366 WP_000285373.1 DUF1033 family protein -
  EGX82_RS04945 (EGX82_04945) rpoC 938291..941941 (-) 3651 WP_000228729.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36851.29 Da        Isoelectric Point: 6.6157

>NTDB_id=326121 EGX82_RS04930 WP_025197279.1 936668..937639(-) (comYA) [Streptococcus agalactiae strain FDAARGOS_512]
MVQSLAKQVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGTRELYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSISGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=326121 EGX82_RS04930 WP_025197279.1 936668..937639(-) (comYA) [Streptococcus agalactiae strain FDAARGOS_512]
ATGGTTCAATCATTAGCAAAGCAAGTCATTCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTAGTTTCATTACGACTATCGAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTACAAGAGAGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTTCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAACTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.167

96.285

0.656
  comYA Streptococcus mutans UA140

68.167

96.285

0.656
  comYA Streptococcus gordonii str. Challis substr. CH1

63.009

98.762

0.622
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.379

96.285

0.601
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.415

96.285

0.591
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.415

96.285

0.591
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.29

95.975

0.588
  comGA Lactococcus lactis subsp. cremoris KW2

50.311

99.69

0.502

Multiple sequence alignment