Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | EGX82_RS04900 | Genome accession | NZ_CP033822 |
| Coordinates | 933182..934156 (-) | Length | 324 a.a. |
| NCBI ID | WP_001008570.1 | Uniprot ID | A0AAW6XQQ3 |
| Organism | Streptococcus agalactiae strain FDAARGOS_512 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 888765..934445 | 933182..934156 | within | 0 |
Gene organization within MGE regions
Location: 888765..934445
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EGX82_RS04640 (EGX82_04640) | - | 888886..889176 (-) | 291 | WP_000158581.1 | DUF5962 family protein | - |
| EGX82_RS04645 (EGX82_04645) | - | 889187..890041 (-) | 855 | WP_000005759.1 | phage replisome organizer N-terminal domain-containing protein | - |
| EGX82_RS04650 (EGX82_04650) | - | 890053..890337 (-) | 285 | WP_001287945.1 | hypothetical protein | - |
| EGX82_RS04655 (EGX82_04655) | - | 890484..891002 (+) | 519 | WP_000181342.1 | helix-turn-helix transcriptional regulator | - |
| EGX82_RS04660 (EGX82_04660) | - | 891057..892211 (+) | 1155 | WP_000110711.1 | site-specific integrase | - |
| EGX82_RS04665 (EGX82_04665) | rpsI | 892357..892749 (-) | 393 | WP_000035940.1 | 30S ribosomal protein S9 | - |
| EGX82_RS04670 (EGX82_04670) | rplM | 892770..893216 (-) | 447 | WP_001867156.1 | 50S ribosomal protein L13 | - |
| EGX82_RS04675 (EGX82_04675) | - | 893517..894683 (+) | 1167 | WP_000160598.1 | IS30-like element ISSag9 family transposase | - |
| EGX82_RS04680 (EGX82_04680) | - | 895001..895120 (-) | 120 | Protein_868 | helix-turn-helix domain-containing protein | - |
| EGX82_RS04690 (EGX82_04690) | - | 895658..896518 (-) | 861 | WP_000143135.1 | DegV family protein | - |
| EGX82_RS04695 (EGX82_04695) | - | 896611..897129 (-) | 519 | WP_000716636.1 | NYN domain-containing protein | - |
| EGX82_RS04700 (EGX82_04700) | rlmB | 897126..897881 (-) | 756 | WP_000178023.1 | 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB | - |
| EGX82_RS04705 (EGX82_04705) | - | 897984..898370 (-) | 387 | WP_000568029.1 | Mini-ribonuclease 3 | - |
| EGX82_RS04710 (EGX82_04710) | cysS | 898363..899706 (-) | 1344 | WP_000591129.1 | cysteine--tRNA ligase | - |
| EGX82_RS04715 (EGX82_04715) | - | 899703..899885 (-) | 183 | WP_000656477.1 | hypothetical protein | - |
| EGX82_RS04720 (EGX82_04720) | cysE | 899895..900479 (-) | 585 | WP_000539954.1 | serine O-acetyltransferase | - |
| EGX82_RS04725 (EGX82_04725) | - | 900488..901240 (-) | 753 | WP_000204780.1 | SseB family protein | - |
| EGX82_RS04730 (EGX82_04730) | pnp | 901242..903371 (-) | 2130 | WP_000043857.1 | polyribonucleotide nucleotidyltransferase | - |
| EGX82_RS04735 (EGX82_04735) | rpsO | 903752..904021 (-) | 270 | WP_001018249.1 | 30S ribosomal protein S15 | - |
| EGX82_RS04740 (EGX82_04740) | - | 904109..905368 (-) | 1260 | WP_001203074.1 | ferric reductase-like transmembrane domain-containing protein | - |
| EGX82_RS04745 (EGX82_04745) | - | 905477..906406 (-) | 930 | WP_001203828.1 | transketolase C-terminal domain-containing protein | - |
| EGX82_RS04750 (EGX82_04750) | - | 906403..907260 (-) | 858 | WP_000203492.1 | transketolase | - |
| EGX82_RS04755 (EGX82_04755) | - | 907263..908618 (-) | 1356 | WP_000677351.1 | PTS ascorbate transporter subunit IIC | - |
| EGX82_RS04760 (EGX82_04760) | - | 908631..908915 (-) | 285 | WP_000944235.1 | PTS sugar transporter subunit IIB | - |
| EGX82_RS04765 (EGX82_04765) | - | 908918..910954 (-) | 2037 | WP_000228178.1 | BglG family transcription antiterminator | - |
| EGX82_RS04770 (EGX82_04770) | treC | 911174..912799 (-) | 1626 | WP_000151014.1 | alpha,alpha-phosphotrehalase | - |
| EGX82_RS04775 (EGX82_04775) | treP | 913021..915051 (-) | 2031 | WP_000434610.1 | PTS system trehalose-specific EIIBC component | - |
| EGX82_RS04780 (EGX82_04780) | - | 915333..915959 (-) | 627 | WP_000171304.1 | ABC transporter ATP-binding protein | - |
| EGX82_RS04785 (EGX82_04785) | - | 915943..916746 (-) | 804 | WP_000140979.1 | ABC transporter ATP-binding protein | - |
| EGX82_RS04790 (EGX82_04790) | - | 916758..917579 (-) | 822 | WP_000603397.1 | ABC transporter permease | - |
| EGX82_RS04795 (EGX82_04795) | - | 917576..918553 (-) | 978 | WP_000680644.1 | ABC transporter permease | - |
| EGX82_RS04800 (EGX82_04800) | - | 918666..920294 (-) | 1629 | WP_000170504.1 | ABC transporter substrate-binding protein | - |
| EGX82_RS04810 (EGX82_04810) | lrgB | 920537..921265 (-) | 729 | WP_000421727.1 | antiholin-like protein LrgB | - |
| EGX82_RS04815 (EGX82_04815) | - | 921267..921722 (-) | 456 | WP_000683316.1 | CidA/LrgA family protein | - |
| EGX82_RS04820 (EGX82_04820) | - | 921892..922632 (-) | 741 | WP_000697630.1 | LytTR family transcriptional regulator DNA-binding domain-containing protein | - |
| EGX82_RS04825 (EGX82_04825) | - | 922613..924358 (-) | 1746 | WP_000930334.1 | LytS/YhcK type 5TM receptor domain-containing protein | - |
| EGX82_RS04830 (EGX82_04830) | - | 924385..925029 (-) | 645 | WP_000416612.1 | HAD family hydrolase | - |
| EGX82_RS04835 (EGX82_04835) | ssbA | 925152..925547 (-) | 396 | WP_000282450.1 | single-stranded DNA-binding protein | Machinery gene |
| EGX82_RS04840 (EGX82_04840) | - | 925628..926344 (+) | 717 | WP_000186183.1 | class I SAM-dependent methyltransferase | - |
| EGX82_RS04845 (EGX82_04845) | ytpR | 926398..927024 (-) | 627 | WP_000578331.1 | YtpR family tRNA-binding protein | - |
| EGX82_RS04850 (EGX82_04850) | - | 927057..927380 (-) | 324 | WP_000601792.1 | thioredoxin family protein | - |
| EGX82_RS04855 (EGX82_04855) | - | 927377..927661 (-) | 285 | WP_000791272.1 | DUF4651 domain-containing protein | - |
| EGX82_RS04860 (EGX82_04860) | - | 927822..928061 (+) | 240 | WP_000660181.1 | hypothetical protein | - |
| EGX82_RS04865 (EGX82_04865) | pepA | 928246..929313 (+) | 1068 | WP_001281321.1 | glutamyl aminopeptidase | - |
| EGX82_RS04870 (EGX82_04870) | proC | 929383..930153 (+) | 771 | WP_001867096.1 | pyrroline-5-carboxylate reductase | - |
| EGX82_RS04875 (EGX82_04875) | - | 930174..930839 (-) | 666 | WP_000008111.1 | type II CAAX endopeptidase family protein | - |
| EGX82_RS04880 (EGX82_04880) | - | 930908..931363 (-) | 456 | WP_000905674.1 | hypothetical protein | - |
| EGX82_RS04885 (EGX82_04885) | - | 931404..931541 (-) | 138 | WP_001867090.1 | hypothetical protein | - |
| EGX82_RS04890 (EGX82_04890) | - | 931600..931806 (-) | 207 | WP_000798242.1 | helix-turn-helix transcriptional regulator | - |
| EGX82_RS04895 (EGX82_04895) | - | 931957..933150 (-) | 1194 | WP_000047535.1 | acetate kinase | - |
| EGX82_RS04900 (EGX82_04900) | comYH | 933182..934156 (-) | 975 | WP_001008570.1 | class I SAM-dependent methyltransferase | Machinery gene |
Sequence
Protein
Download Length: 324 a.a. Molecular weight: 37100.99 Da Isoelectric Point: 4.4041
>NTDB_id=326118 EGX82_RS04900 WP_001008570.1 933182..934156(-) (comYH) [Streptococcus agalactiae strain FDAARGOS_512]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE
Nucleotide
Download Length: 975 bp
>NTDB_id=326118 EGX82_RS04900 WP_001008570.1 933182..934156(-) (comYH) [Streptococcus agalactiae strain FDAARGOS_512]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.984 |
97.222 |
0.651 |
| comYH | Streptococcus mutans UA140 |
66.984 |
97.222 |
0.651 |