Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssb   Type   Machinery gene
Locus tag   EGX72_RS02745 Genome accession   NZ_CP033809
Coordinates   477945..478361 (+) Length   138 a.a.
NCBI ID   WP_000609565.1    Uniprot ID   Q8DXI7
Organism   Streptococcus sp. FDAARGOS_521     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 466006..501798 477945..478361 within 0


Gene organization within MGE regions


Location: 466006..501798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX72_RS02640 (EGX72_02635) - 466006..467073 (-) 1068 WP_000332283.1 site-specific integrase -
  EGX72_RS02645 (EGX72_02640) - 467197..467601 (-) 405 WP_123957713.1 DUF4429 domain-containing protein -
  EGX72_RS02650 (EGX72_02645) - 467623..468369 (-) 747 WP_000878006.1 ImmA/IrrE family metallo-endopeptidase -
  EGX72_RS02655 (EGX72_02650) - 468378..468758 (-) 381 WP_000466347.1 helix-turn-helix domain-containing protein -
  EGX72_RS02660 (EGX72_02655) - 469046..469210 (+) 165 WP_000511144.1 hypothetical protein -
  EGX72_RS02665 (EGX72_02660) - 469193..469663 (-) 471 WP_001052629.1 hypothetical protein -
  EGX72_RS02670 (EGX72_02665) - 469724..469936 (+) 213 WP_000082754.1 helix-turn-helix transcriptional regulator -
  EGX72_RS02675 (EGX72_02670) - 469936..470181 (+) 246 WP_301182292.1 hypothetical protein -
  EGX72_RS02680 (EGX72_02675) - 470323..470853 (+) 531 WP_001006993.1 NUMOD4 domain-containing protein -
  EGX72_RS02685 (EGX72_02680) - 470853..471137 (+) 285 WP_000998974.1 hypothetical protein -
  EGX72_RS02690 (EGX72_02685) - 471161..471379 (+) 219 WP_001061695.1 hypothetical protein -
  EGX72_RS02695 (EGX72_02690) dnaB 471388..472719 (+) 1332 WP_000343910.1 replicative DNA helicase -
  EGX72_RS02700 (EGX72_02695) - 472721..473323 (+) 603 WP_000712924.1 hypothetical protein -
  EGX72_RS02705 (EGX72_02700) - 473301..474047 (+) 747 WP_000079055.1 conserved phage C-terminal domain-containing protein -
  EGX72_RS02710 (EGX72_02705) - 474048..474869 (+) 822 WP_001067868.1 ATP-binding protein -
  EGX72_RS02715 (EGX72_02710) - 474869..476182 (+) 1314 WP_000670039.1 DNA cytosine methyltransferase -
  EGX72_RS02720 (EGX72_02715) - 476179..476583 (+) 405 WP_000220554.1 hypothetical protein -
  EGX72_RS02725 (EGX72_02720) - 476576..477067 (+) 492 WP_000169322.1 MazG-like family protein -
  EGX72_RS02730 (EGX72_02725) - 477067..477396 (+) 330 WP_000793494.1 DUF1372 family protein -
  EGX72_RS11790 (EGX72_02730) - 477396..477752 (+) 357 WP_000158822.1 DUF3310 domain-containing protein -
  EGX72_RS02740 (EGX72_02735) - 477749..477955 (+) 207 WP_000748199.1 hypothetical protein -
  EGX72_RS02745 (EGX72_02740) ssb 477945..478361 (+) 417 WP_000609565.1 single-stranded DNA-binding protein Machinery gene
  EGX72_RS02755 (EGX72_02750) ltrA 478942..480261 (+) 1320 WP_000561483.1 group II intron reverse transcriptase/maturase -
  EGX72_RS02760 (EGX72_02755) - 480394..480654 (+) 261 WP_001008140.1 hypothetical protein -
  EGX72_RS02765 (EGX72_02760) - 480651..480998 (+) 348 WP_000776714.1 helix-turn-helix domain-containing protein -
  EGX72_RS02770 (EGX72_02765) - 480995..481459 (+) 465 WP_000163169.1 hypothetical protein -
  EGX72_RS02775 (EGX72_02770) - 481569..482111 (+) 543 WP_001028147.1 site-specific integrase -
  EGX72_RS02780 (EGX72_02775) - 482401..482688 (+) 288 WP_000651008.1 hypothetical protein -
  EGX72_RS02785 (EGX72_02780) - 482811..483047 (+) 237 WP_253257054.1 HNH endonuclease -
  EGX72_RS02790 (EGX72_02785) - 483135..483620 (+) 486 WP_000601033.1 hypothetical protein -
  EGX72_RS02795 (EGX72_02790) - 483613..485325 (+) 1713 WP_000230004.1 terminase TerL endonuclease subunit -
  EGX72_RS02800 (EGX72_02795) - 485334..486476 (+) 1143 WP_001067328.1 phage portal protein -
  EGX72_RS02805 (EGX72_02800) - 486526..487068 (+) 543 WP_000413200.1 HK97 family phage prohead protease -
  EGX72_RS02810 (EGX72_02805) - 487079..488341 (+) 1263 WP_000749069.1 phage major capsid protein -
  EGX72_RS02815 (EGX72_02810) - 488362..488697 (+) 336 WP_000153862.1 hypothetical protein -
  EGX72_RS02820 (EGX72_02815) - 488694..488999 (+) 306 WP_000842788.1 head-tail adaptor protein -
  EGX72_RS02825 (EGX72_02820) - 488999..489346 (+) 348 WP_001074485.1 hypothetical protein -
  EGX72_RS02830 (EGX72_02825) - 489333..489677 (+) 345 WP_000508737.1 hypothetical protein -
  EGX72_RS02835 (EGX72_02830) - 489692..490375 (+) 684 WP_000222195.1 hypothetical protein -
  EGX72_RS02840 (EGX72_02835) - 490375..490851 (+) 477 WP_000591556.1 hypothetical protein -
  EGX72_RS02850 (EGX72_02845) - 491037..493772 (+) 2736 WP_000140777.1 phage tail tape measure protein -
  EGX72_RS02855 (EGX72_02850) - 493769..494491 (+) 723 WP_000161556.1 hypothetical protein -
  EGX72_RS02860 (EGX72_02855) - 494492..498166 (+) 3675 WP_001880132.1 phage tail spike protein -
  EGX72_RS02865 (EGX72_02860) - 498183..498413 (+) 231 WP_001071123.1 hypothetical protein -
  EGX72_RS02870 (EGX72_02865) - 498416..498754 (+) 339 WP_000213864.1 hypothetical protein -
  EGX72_RS02875 (EGX72_02870) - 498789..499199 (+) 411 WP_001135353.1 hypothetical protein -
  EGX72_RS02880 (EGX72_02875) - 499202..499531 (+) 330 WP_000192161.1 phage holin -
  EGX72_RS02885 (EGX72_02880) - 499535..500941 (+) 1407 WP_000405193.1 peptidoglycan amidohydrolase family protein -
  EGX72_RS02890 (EGX72_02885) - 501148..501333 (+) 186 WP_000139836.1 type II toxin-antitoxin system HicA family toxin -
  EGX72_RS02895 (EGX72_02890) - 501394..501798 (+) 405 WP_000878124.1 type II toxin-antitoxin system HicB family antitoxin -

Sequence


Protein


Download         Length: 138 a.a.        Molecular weight: 15674.52 Da        Isoelectric Point: 4.6604

>NTDB_id=325867 EGX72_RS02745 WP_000609565.1 477945..478361(+) (ssb) [Streptococcus sp. FDAARGOS_521]
MINNVVLIGRLTRDVELRYTPSNIANATFNLAVNRNFKNAAGDREADFINCVMWRQQAENLANWTKKGMLIGITGRIQTR
SYENQQGQRIYVTEVVADSFQILEKRDNSTNQASMDDQLPPSFGNSQPMDISDDDLPF

Nucleotide


Download         Length: 417 bp        

>NTDB_id=325867 EGX72_RS02745 WP_000609565.1 477945..478361(+) (ssb) [Streptococcus sp. FDAARGOS_521]
ATGATCAATAATGTTGTACTTATTGGCCGCTTGACAAGAGATGTTGAGCTACGTTACACGCCGTCAAACATCGCAAACGC
TACTTTTAACCTAGCAGTCAATCGAAATTTCAAGAATGCTGCTGGTGATCGTGAAGCTGATTTCATCAACTGTGTGATGT
GGCGACAACAAGCTGAAAACTTGGCCAATTGGACGAAAAAAGGAATGCTGATTGGTATTACTGGACGAATCCAGACAAGA
AGCTACGAAAATCAGCAAGGTCAGCGTATCTATGTGACTGAGGTTGTTGCTGACAGCTTCCAGATTCTTGAAAAGCGTGA
TAATTCAACGAACCAGGCAAGCATGGATGACCAATTGCCACCATCATTTGGAAATAGTCAGCCTATGGATATTTCAGATG
ATGATCTACCGTTTTGA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB Q8DXI7

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssb Latilactobacillus sakei subsp. sakei 23K

54.118

100

0.667

  ssbA Bacillus subtilis subsp. subtilis str. 168

50.575

100

0.638

  ssbB/cilA Streptococcus pneumoniae TIGR4

41.259

100

0.428

  ssbB Bacillus subtilis subsp. subtilis str. 168

54.717

76.812

0.42

  ssbB/cilA Streptococcus pneumoniae R6

40.559

100

0.42

  ssbB/cilA Streptococcus mitis SK321

40.559

100

0.42

  ssbB/cilA Streptococcus mitis NCTC 12261

40.559

100

0.42

  ssbB/cilA Streptococcus pneumoniae Rx1

40.559

100

0.42

  ssbB/cilA Streptococcus pneumoniae D39

40.559

100

0.42

  ssbB Streptococcus sobrinus strain NIDR 6715-7

50.943

76.812

0.391


Multiple sequence alignment