Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EB817_RS04845 Genome accession   NZ_CP033336
Coordinates   927367..928209 (-) Length   280 a.a.
NCBI ID   WP_129304691.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY165     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 922367..933209
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EB817_RS04825 (EB817_04830) - 922630..923581 (-) 952 Protein_863 D-lactate dehydrogenase -
  EB817_RS04830 (EB817_04835) - 923596..924162 (-) 567 Protein_864 PTS sugar transporter subunit IIC -
  EB817_RS04835 (EB817_04840) - 924175..925059 (+) 885 Protein_865 LysR family transcriptional regulator -
  EB817_RS04840 (EB817_04845) topA 925135..927267 (-) 2133 WP_129304689.1 type I DNA topoisomerase -
  EB817_RS04845 (EB817_04850) dprA 927367..928209 (-) 843 WP_129304691.1 DNA-processing protein DprA Machinery gene
  EB817_RS04850 (EB817_04855) - 928274..929065 (-) 792 WP_129304693.1 ribonuclease HII -
  EB817_RS04855 (EB817_04860) ylqF 929055..929903 (-) 849 WP_129304695.1 ribosome biogenesis GTPase YlqF -
  EB817_RS04860 (EB817_04865) - 930122..930562 (+) 441 WP_002989774.1 DUF1836 domain-containing protein -
  EB817_RS04865 (EB817_04870) - 930559..931209 (+) 651 WP_002984629.1 hemolysin III family protein -
  EB817_RS04870 (EB817_04875) - 931326..932237 (+) 912 WP_129304697.1 diacylglycerol kinase family protein -
  EB817_RS04875 (EB817_04880) - 932287..932727 (-) 441 WP_024623381.1 hypothetical protein -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31391.44 Da        Isoelectric Point: 9.2510

>NTDB_id=323080 EB817_RS04845 WP_129304691.1 927367..928209(-) (dprA) [Streptococcus pyogenes strain TSPY165]
MNHFELYKLKKARLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIETYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLDKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AVIGTGLDRFYPKENQELQTFLGRKHLILTEYGPGEEPLSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGESEGCLQLIKEGATCVTSGMDILSEYQK

Nucleotide


Download         Length: 843 bp        

>NTDB_id=323080 EB817_RS04845 WP_129304691.1 927367..928209(-) (dprA) [Streptococcus pyogenes strain TSPY165]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAGGCTAGACTGACTAATAAAAATATTCTCAATATTCTTGACTACCAAAA
GCAACAGGAAAAATCGTTGTCGCTTCGAGACATGGCCGTTGTTTCCGGTTGTAAGCACCCGTCTCACTTTATAGAAACCT
ATAAGCAGTTAGATATCCAAAAGTTAAAAATGGAATTTAAACAATTCCCTAGTATTTCTATCCTAGATAAACATTACCCA
ATGGCTTTGAAAGAAATATATAATCCGCCCGTCCTCTTGTTTTTTCAAGGCAATTTAGACCTTCTTGATAAACCTAAATT
AGCCATTGTGGGCTCAAGGCGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTCAGCGGACTTGCTCGAGGTATTGACACTAGTGCACATTTAGCCTGTCTTAAAAACGGAGGACAAACCATT
GCGGTGATAGGAACAGGATTAGACCGTTTTTATCCCAAAGAAAATCAAGAATTACAAACATTCTTAGGAAGGAAACACCT
TATCTTGACGGAATACGGTCCAGGAGAAGAACCACTATCGTATCACTTTCCGGAACGCAATCGTATTATTGCAGGGCTTA
GTCGAGGTATTCTCGTCGTTGAAGCAAAAAATCGCTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAGGGTCGA
GATATTTTTGCTGTTCCAGGAAACATTTTGGACGGCGAATCTGAAGGTTGTTTACAGCTTATAAAAGAGGGAGCAACCTG
CGTCACATCAGGGATGGACATCCTTTCTGAATATCAAAAATAA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(68-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

66.547

99.286

0.661
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

60.215

99.643

0.6
  dprA/cilB/dalA Streptococcus pneumoniae D39

60.215

99.643

0.6
  dprA/cilB/dalA Streptococcus pneumoniae R6

60.215

99.643

0.6
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

60.215

99.643

0.6
  dprA/cilB/dalA Streptococcus mitis SK321

60.215

99.643

0.6
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

59.857

99.643

0.596
  dprA Lactococcus lactis subsp. cremoris KW2

56.835

99.286

0.564
  dprA Acinetobacter baumannii D1279779

36.842

100

0.375
  dprA Acinetobacter baumannii strain A118

35.739

100

0.371
  dprA Legionella pneumophila strain ERS1305867

43.333

85.714

0.371
  dprA Haemophilus influenzae Rd KW20

38.202

95.357

0.364

Multiple sequence alignment