Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   D7D50_RS03160 Genome accession   NZ_CP032620
Coordinates   573121..573873 (+) Length   250 a.a.
NCBI ID   WP_023024804.1    Uniprot ID   -
Organism   Streptococcus koreensis strain KCOM 2890 (=JS71)     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 568121..578873
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D7D50_RS03130 (D7D50_03130) spo0J 568612..569373 (-) 762 WP_120701436.1 ParB/RepB/Spo0J family partition protein Regulator
  D7D50_RS03135 (D7D50_03135) htrA 569439..570617 (-) 1179 WP_120701437.1 S1C family serine protease Regulator
  D7D50_RS03140 (D7D50_03140) rlmH 570820..571299 (+) 480 WP_120701438.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  D7D50_RS03150 (D7D50_03150) - 571658..571801 (+) 144 WP_117744856.1 bacteriocin -
  D7D50_RS10215 - 571801..573120 (+) 1320 WP_227877756.1 sensor histidine kinase -
  D7D50_RS03160 (D7D50_03160) comE/comE2 573121..573873 (+) 753 WP_023024804.1 response regulator transcription factor Regulator
  D7D50_RS03180 (D7D50_03180) - 574306..576894 (-) 2589 WP_120701439.1 YfhO family protein -
  D7D50_RS03185 (D7D50_03185) - 576957..578579 (-) 1623 WP_120701440.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29425.19 Da        Isoelectric Point: 8.4063

>NTDB_id=317132 D7D50_RS03160 WP_023024804.1 573121..573873(+) (comE/comE2) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
MNIVLLEDEISQQVRVEKHVKAIAEEEGLRLNIVSTSKITELKEYLTNGDFHQLFFLDIDIKGDEKAGIKAAQMIREVNP
FAIIAFITTKSEFATITYRYKVSALEFIEKTLNENLFKEKIRECILYLKKNVIENKNIVDFFEYSFKNMEIRVPYRDILY
IETTGVSHKLRLVGKNFQKEFLGTIKDILEKDVDNHFFSPNQSYLVNQRMIVNFDRRKRLLMLEEETTCPVSRTQVKKVE
ELLNKIQKKA

Nucleotide


Download         Length: 753 bp        

>NTDB_id=317132 D7D50_RS03160 WP_023024804.1 573121..573873(+) (comE/comE2) [Streptococcus koreensis strain KCOM 2890 (=JS71)]
ATGAATATTGTATTGCTAGAGGACGAAATTTCTCAACAAGTTCGAGTAGAGAAACATGTGAAAGCTATCGCTGAGGAGGA
AGGCCTACGATTAAATATTGTTTCAACCAGTAAAATAACTGAACTAAAGGAATATCTAACCAATGGTGATTTTCATCAGC
TTTTCTTCCTTGACATTGATATCAAAGGGGATGAAAAAGCTGGTATCAAGGCAGCTCAAATGATTCGTGAAGTTAATCCT
TTTGCGATTATTGCCTTTATCACGACGAAATCGGAATTTGCTACCATTACCTATCGTTACAAGGTATCAGCTCTCGAATT
TATTGAAAAAACCTTGAATGAAAACTTGTTTAAAGAAAAAATTCGAGAATGTATTCTCTACTTGAAGAAGAATGTGATTG
AAAATAAAAATATCGTTGATTTCTTTGAGTATAGTTTCAAAAATATGGAAATTCGAGTTCCATATCGAGATATATTGTAC
ATTGAGACAACTGGAGTTTCCCACAAATTGCGACTTGTTGGAAAGAATTTTCAAAAGGAATTTTTAGGGACTATCAAGGA
TATACTTGAAAAAGATGTAGACAATCATTTCTTCAGTCCCAATCAGTCCTATCTAGTGAATCAAAGAATGATTGTCAACT
TTGATCGTCGCAAGAGACTCTTGATGTTAGAAGAGGAGACAACTTGCCCTGTCTCTCGTACACAGGTGAAAAAGGTCGAA
GAATTATTAAATAAAATACAGAAAAAGGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(18-121)

LytTr DNA-binding domain (LytTR)

(151-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

50.4

100

0.504
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

50.4

100

0.504
  comE Streptococcus infantis strain Atu-4

49.6

100

0.496
  comE Streptococcus mitis SK321

48.4

100

0.484
  comE Streptococcus mitis NCTC 12261

48.4

100

0.484
  comE Streptococcus pneumoniae Rx1

47.6

100

0.476
  comE Streptococcus pneumoniae D39

47.6

100

0.476
  comE Streptococcus pneumoniae R6

47.6

100

0.476
  comE Streptococcus pneumoniae TIGR4

47.6

100

0.476
  comE/comE1 Streptococcus equinus JB1

38.211

98.4

0.376

Multiple sequence alignment