Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DDV21_RS11305 Genome accession   NZ_CP031733
Coordinates   2358006..2359265 (-) Length   419 a.a.
NCBI ID   WP_116877801.1    Uniprot ID   A0A372KMJ2
Organism   Streptococcus chenjunshii strain Z15     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2353006..2364265
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DDV21_RS11270 (DDV21_011270) - 2353075..2353374 (-) 300 WP_116877807.1 DUF1292 domain-containing protein -
  DDV21_RS11275 (DDV21_011275) ruvX 2353430..2353849 (-) 420 WP_116877806.1 Holliday junction resolvase RuvX -
  DDV21_RS11280 (DDV21_011280) - 2353846..2354115 (-) 270 WP_116877805.1 IreB family regulatory phosphoprotein -
  DDV21_RS11285 (DDV21_011285) brsR 2354418..2354858 (+) 441 WP_116877804.1 LytTR family DNA-binding domain-containing protein Regulator
  DDV21_RS11290 (DDV21_011290) - 2355250..2355711 (+) 462 WP_116877803.1 DUF3021 domain-containing protein -
  DDV21_RS11295 (DDV21_011295) spx 2355901..2356299 (-) 399 WP_067064532.1 transcriptional regulator Spx -
  DDV21_RS11300 (DDV21_011300) recA 2356694..2357848 (-) 1155 WP_116877802.1 recombinase RecA Machinery gene
  DDV21_RS11305 (DDV21_011305) cinA 2358006..2359265 (-) 1260 WP_116877801.1 competence/damage-inducible protein A Machinery gene
  DDV21_RS11310 (DDV21_011310) - 2359346..2359909 (-) 564 WP_116877800.1 DNA-3-methyladenine glycosylase I -
  DDV21_RS11315 (DDV21_011315) ruvA 2360691..2361284 (-) 594 WP_116877799.1 Holliday junction branch migration protein RuvA -
  DDV21_RS11320 (DDV21_011320) mutL 2361300..2363237 (-) 1938 WP_116877798.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45292.95 Da        Isoelectric Point: 7.9648

>NTDB_id=310864 DDV21_RS11305 WP_116877801.1 2358006..2359265(-) (cinA) [Streptococcus chenjunshii strain Z15]
MRAEIIAVGTELLTGQIVNTNAQFLSEKFAELGIDVFFQTAVGDNEKRLLSVIDIASRRSNLVVLCGGLGPTEDDLTKQT
LAKYLGRDLVFDGQAVQRLDAFFAERPQHTRTPNNERQAQLIAGSSPLQNNNGLAVGGVLEQNGVTYVVLPGPPSELKPM
VLEQLVPLLGQGKQRLYSRVLRFFGIGESQLVTVLADFIEEQTDPTVAPYAKIGEVTLRLSTKAPSQKDADLKLDRLEKK
ILAVKTLDGLRLSDLHYGYGDDNSLAQTVFELLKKNKKTVTAAESLTAGLFQSSLAEFSGASQVFSGGFITYSIEEKAKM
LKIPLADLRANGVVSSFTAERMAAQARLLTGADFGIGLTGVAGPEELEKQPAGTVFIGLSSKDRLYSIKLSLGGRSRSDV
RYIAALSAFNLIRQALLKG

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=310864 DDV21_RS11305 WP_116877801.1 2358006..2359265(-) (cinA) [Streptococcus chenjunshii strain Z15]
ATGAGAGCTGAAATTATTGCGGTAGGGACTGAATTGCTAACAGGGCAGATTGTAAATACCAATGCTCAATTTCTATCTGA
AAAGTTTGCTGAGCTGGGTATCGATGTTTTTTTTCAAACAGCGGTAGGAGATAATGAAAAGCGTCTTTTATCTGTGATTG
ATATTGCCAGCAGACGCAGCAATCTTGTTGTCCTTTGCGGAGGGCTTGGTCCGACAGAAGATGATTTAACAAAGCAAACT
CTGGCAAAATATTTAGGCCGGGACTTGGTATTCGACGGTCAGGCAGTCCAGCGTTTAGATGCTTTTTTTGCGGAACGTCC
TCAGCATACCAGAACACCGAATAATGAGAGGCAGGCTCAACTGATTGCCGGTTCATCCCCTTTGCAAAACAATAACGGTC
TGGCAGTGGGAGGTGTGCTTGAGCAGAACGGAGTAACCTATGTTGTTCTGCCGGGCCCTCCTAGTGAACTGAAACCTATG
GTTTTAGAACAGCTTGTTCCTCTTTTGGGACAGGGTAAACAGCGGCTGTACTCCCGTGTTTTACGGTTTTTTGGCATTGG
CGAAAGTCAGCTGGTTACTGTTTTAGCGGATTTTATTGAAGAGCAGACAGACCCTACTGTAGCTCCTTACGCTAAAATCG
GCGAGGTGACTCTACGGTTATCTACTAAAGCCCCCAGCCAAAAGGATGCTGATTTAAAACTTGACCGGCTGGAAAAGAAG
ATTTTGGCAGTAAAAACTCTGGATGGACTTAGATTAAGCGATTTGCATTATGGATATGGTGATGATAACAGTCTGGCCCA
AACTGTCTTTGAACTGCTTAAAAAAAATAAAAAGACTGTGACGGCAGCAGAGAGTCTCACGGCAGGTTTATTTCAATCCA
GTTTGGCAGAATTTTCCGGTGCTTCTCAGGTTTTTAGCGGCGGTTTTATAACTTACAGTATAGAAGAAAAGGCAAAAATG
CTGAAAATCCCGCTTGCAGATTTACGGGCTAACGGAGTAGTCAGCTCTTTTACTGCTGAGCGAATGGCTGCACAAGCTCG
CTTGTTGACTGGTGCGGATTTTGGTATAGGACTGACAGGAGTCGCAGGACCGGAGGAGCTGGAAAAGCAGCCGGCAGGTA
CAGTTTTTATCGGTCTTTCCAGTAAAGACAGACTTTATTCGATTAAGCTCAGCTTAGGGGGACGCAGCCGTTCCGATGTG
CGCTATATTGCCGCGCTGTCTGCTTTCAATTTGATACGTCAAGCTTTATTAAAAGGCTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A372KMJ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

71.703

99.523

0.714
  cinA Streptococcus mitis SK321

69.784

99.523

0.695
  cinA Streptococcus mitis NCTC 12261

69.065

99.523

0.687
  cinA Streptococcus pneumoniae TIGR4

67.626

99.523

0.673
  cinA Streptococcus pneumoniae Rx1

67.626

99.523

0.673
  cinA Streptococcus pneumoniae R6

67.626

99.523

0.673
  cinA Streptococcus pneumoniae D39

67.386

99.523

0.671
  cinA Streptococcus suis isolate S10

54.567

99.284

0.542
  cinA Bacillus subtilis subsp. subtilis str. 168

44.976

99.761

0.449

Multiple sequence alignment