Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DK237_RS00385 Genome accession   NZ_CP031377
Coordinates   67231..68412 (+) Length   393 a.a.
NCBI ID   WP_004194467.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2614     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 62231..73412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK237_RS00370 (DK237_00375) mutL 63805..65742 (+) 1938 WP_053861385.1 DNA mismatch repair endonuclease MutL -
  DK237_RS00375 (DK237_00380) ruvA 65781..66371 (+) 591 WP_004194470.1 Holliday junction branch migration protein RuvA -
  DK237_RS00380 (DK237_00385) - 66625..67194 (+) 570 WP_004194469.1 DNA-3-methyladenine glycosylase I -
  DK237_RS00385 (DK237_00390) cinA 67231..68412 (+) 1182 WP_004194467.1 competence/damage-inducible protein A Machinery gene
  DK237_RS00390 (DK237_00395) recA 68464..69615 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  DK237_RS00395 (DK237_00400) spx 69851..70249 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  DK237_RS00400 (DK237_00405) - 70349..70615 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  DK237_RS00405 (DK237_00410) ruvX 70615..71034 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  DK237_RS00410 (DK237_00415) - 71046..71366 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  DK237_RS00415 (DK237_00420) - 71624..72202 (+) 579 WP_044667815.1 nucleotidyltransferase family protein -
  DK237_RS00420 (DK237_00425) comX/sigX 72275..72541 (+) 267 WP_002939335.1 hypothetical protein Regulator
  DK237_RS00425 (DK237_00430) rpsJ 72863..73171 (+) 309 WP_013730061.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 43013.95 Da        Isoelectric Point: 4.4112

>NTDB_id=306316 DK237_RS00385 WP_004194467.1 67231..68412(+) (cinA) [Streptococcus suis strain ISU2614]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEVARQRSDLVILCGGLGPTEDDLTKQI
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRILRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=306316 DK237_RS00385 WP_004194467.1 67231..68412(+) (cinA) [Streptococcus suis strain ISU2614]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTCTATTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACCTGGTCATTCTCTGTGGAGGATTGGGTCCAACTGAGGATGACTTGACCAAGCAGATC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTATCCTACGTTTTTTTGGCATTGG
TGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATCGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTAAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

95.929

100

0.959
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus pneumoniae R6

55.769

100

0.59
  cinA Streptococcus mitis SK321

55.769

100

0.59
  cinA Streptococcus pneumoniae TIGR4

55.769

100

0.59
  cinA Streptococcus pneumoniae Rx1

55.769

100

0.59
  cinA Streptococcus mitis NCTC 12261

55.529

100

0.588
  cinA Streptococcus pneumoniae D39

55.529

100

0.588
  cinA Bacillus subtilis subsp. subtilis str. 168

40.665

99.491

0.405

Multiple sequence alignment