Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   EW997_RS17215 Genome accession   NZ_CP035879
Coordinates   3502656..3503288 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain DS26-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3497656..3508288
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW997_RS17190 yhfG 3497788..3497955 (+) 168 WP_000736862.1 YhfG family protein -
  EW997_RS17195 fic 3497945..3498547 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  EW997_RS17200 pabA 3498579..3499142 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  EW997_RS17205 argD 3499228..3500448 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  EW997_RS17210 yhfK 3500515..3502605 (-) 2091 WP_001364263.1 YccS/YhfK family putative transporter -
  EW997_RS17215 crp 3502656..3503288 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  EW997_RS17220 yhfA 3503590..3503994 (+) 405 WP_001148908.1 OsmC family protein -
  EW997_RS17225 prkB 3504049..3504918 (-) 870 WP_001274680.1 phosphoribulokinase -
  EW997_RS17230 yheU 3504972..3505190 (-) 219 WP_000907085.1 YheU family protein -
  EW997_RS17235 yheT 3505184..3506206 (-) 1023 WP_001364264.1 hydrolase -
  EW997_RS17240 yheS 3506206..3508119 (-) 1914 WP_000634798.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=306318 EW997_RS17215 WP_000242755.1 3502656..3503288(-) (crp) [Escherichia coli strain DS26-1]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=306318 EW997_RS17215 WP_000242755.1 3502656..3503288(-) (crp) [Escherichia coli strain DS26-1]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment