Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   UCCLBBS449_RS04545 Genome accession   NZ_CP031198
Coordinates   952228..953478 (+) Length   416 a.a.
NCBI ID   WP_011667974.1    Uniprot ID   M5AZ98
Organism   Levilactobacillus brevis strain UCCLBBS449     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 947228..958478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  UCCLBBS449_RS04525 (UCCLBBS449_0885) yfmF 947942..949237 (+) 1296 WP_042522427.1 EF-P 5-aminopentanol modification-associated protein YfmF -
  UCCLBBS449_RS04530 (UCCLBBS449_0886) yfmH 949215..950504 (+) 1290 WP_021742877.1 EF-P 5-aminopentanol modification-associated protein YfmH -
  UCCLBBS449_RS04535 (UCCLBBS449_0887) - 950618..951523 (+) 906 WP_011668110.1 helix-turn-helix domain-containing protein -
  UCCLBBS449_RS04540 (UCCLBBS449_0888) pgsA 951585..952172 (+) 588 WP_011668109.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  UCCLBBS449_RS04545 (UCCLBBS449_0889) cinA 952228..953478 (+) 1251 WP_011667974.1 competence/damage-inducible protein A Machinery gene
  UCCLBBS449_RS04550 (UCCLBBS449_0890) recA 953572..954705 (+) 1134 WP_011667973.1 recombinase RecA Machinery gene
  UCCLBBS449_RS13890 (UCCLBBS449_0891) - 954788..954940 (-) 153 WP_021742880.1 hypothetical protein -
  UCCLBBS449_RS04555 (UCCLBBS449_0892) rny 955268..956827 (+) 1560 WP_011667971.1 ribonuclease Y -
  UCCLBBS449_RS04560 (UCCLBBS449_0893) - 956959..957753 (+) 795 WP_024525499.1 TIGR00282 family metallophosphoesterase -

Sequence

Protein


Download         Length: 416 a.a.        Molecular weight: 44778.88 Da        Isoelectric Point: 5.2849

>NTDB_id=304037 UCCLBBS449_RS04545 WP_011667974.1 952228..953478(+) (cinA) [Levilactobacillus brevis strain UCCLBBS449]
MQAEIIAVGTEILLGQIVDTNSAFIARELAEAGIEVYYHSLVGDNATRLTAVVEQARSRSDLVIISGGLGPTKDDLTKQT
VAHLLGVKLVEDALAMAKIRRRFAINGREMTPNNRLQALYPAGSQPLANRTGLAVGAFYQDPDGADIMLLPGPPSETEPM
FREQALPLLKQTYPRSEYLSSRVLRFFGIGESQLVTQLSDLIDQQTNPTIAPYAKVNEVTLRLTAQAPDEMQGQRLLDDL
TATIKARVGDYLYGYGDDNSLAAVVVQTLIDRQLTITAAESLTAGQFQSTLGSVPGVSAVFPGGFVTYAASAKHDLLGVS
QATIDQDGVVSAATAKEMASRSRERLDTDFSLSFTGVAGPDALEGQPAGTVWLGLAQRGQQPQAKLLHLTGTRSAIRERS
VLTGLDWLRRTLQKVK

Nucleotide


Download         Length: 1251 bp        

>NTDB_id=304037 UCCLBBS449_RS04545 WP_011667974.1 952228..953478(+) (cinA) [Levilactobacillus brevis strain UCCLBBS449]
GTGCAAGCAGAAATTATTGCGGTTGGTACAGAGATTTTACTCGGGCAAATTGTGGATACGAACTCTGCCTTCATTGCGCG
CGAACTGGCGGAAGCTGGGATTGAGGTGTATTACCATTCTCTAGTAGGTGATAACGCAACCCGGTTAACGGCTGTTGTTG
AACAAGCCCGTTCGCGGAGCGATTTAGTGATTATTAGTGGGGGATTAGGACCGACCAAAGATGATTTGACAAAACAAACG
GTCGCTCACTTGCTAGGCGTAAAGTTGGTTGAAGATGCGTTGGCAATGGCTAAGATTCGTCGCCGGTTTGCTATCAATGG
CCGTGAGATGACGCCTAATAATCGCCTACAAGCTTTATATCCAGCAGGCAGTCAACCCTTAGCAAATCGGACTGGGTTAG
CTGTGGGAGCTTTTTATCAAGATCCTGATGGTGCGGACATCATGCTATTACCGGGACCACCAAGTGAGACTGAACCCATG
TTTCGTGAGCAAGCCTTACCCCTGCTGAAGCAAACATATCCACGGAGTGAGTACTTGTCTTCACGGGTACTTCGGTTCTT
TGGCATCGGCGAAAGTCAATTGGTCACTCAACTGAGTGATCTGATTGACCAGCAGACTAATCCGACCATCGCTCCTTATG
CTAAAGTTAATGAAGTAACGTTACGTTTAACCGCACAGGCCCCTGATGAGATGCAAGGGCAACGCCTCTTAGATGACTTA
ACGGCGACGATTAAGGCCCGCGTAGGGGATTATCTTTATGGTTATGGTGATGATAATTCATTGGCGGCAGTGGTGGTTCA
GACACTAATTGACCGTCAATTGACCATTACGGCTGCTGAGAGCTTAACGGCCGGTCAATTTCAAAGTACCTTGGGAAGTG
TTCCCGGTGTTTCGGCGGTTTTCCCTGGTGGTTTTGTCACCTATGCGGCCAGTGCCAAGCATGACTTATTGGGAGTCTCG
CAGGCCACGATTGATCAAGATGGTGTGGTTAGTGCGGCCACAGCTAAGGAAATGGCATCACGTTCTCGAGAACGGCTGGA
TACTGATTTTTCGTTGAGCTTCACGGGAGTTGCTGGCCCGGACGCCTTGGAAGGCCAACCGGCTGGAACAGTCTGGTTAG
GTTTAGCGCAACGGGGGCAACAACCACAGGCAAAACTGTTACATTTGACGGGTACGCGATCGGCAATTCGGGAACGGAGT
GTCTTGACCGGGTTGGACTGGTTGCGACGAACATTGCAAAAAGTAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(181-254)

Competence-damaged protein (CinA)

(259-412)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB M5AZ98

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

51.566

99.76

0.514
  cinA Streptococcus mitis NCTC 12261

49.644

100

0.502
  cinA Streptococcus mitis SK321

49.762

100

0.502
  cinA Streptococcus pneumoniae TIGR4

48.694

100

0.493
  cinA Streptococcus pneumoniae Rx1

48.694

100

0.493
  cinA Streptococcus pneumoniae R6

48.694

100

0.493
  cinA Streptococcus pneumoniae D39

48.456

100

0.49
  cinA Bacillus subtilis subsp. subtilis str. 168

47.7

99.279

0.474
  cinA Streptococcus suis isolate S10

44.471

100

0.445

Multiple sequence alignment