Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DP112_RS00375 Genome accession   NZ_CP030125
Coordinates   63099..64280 (+) Length   393 a.a.
NCBI ID   WP_114866096.1    Uniprot ID   -
Organism   Streptococcus suis strain HA1003     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 58099..69280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP112_RS00360 (DP112_00360) mutL 59686..61623 (+) 1938 WP_029172056.1 DNA mismatch repair endonuclease MutL -
  DP112_RS00365 (DP112_00365) ruvA 61662..62252 (+) 591 WP_114866094.1 Holliday junction branch migration protein RuvA -
  DP112_RS00370 (DP112_00370) - 62493..63062 (+) 570 WP_114866095.1 DNA-3-methyladenine glycosylase I -
  DP112_RS00375 (DP112_00375) cinA 63099..64280 (+) 1182 WP_114866096.1 competence/damage-inducible protein A Machinery gene
  DP112_RS00380 (DP112_00380) recA 64332..65483 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  DP112_RS00385 (DP112_00385) spx 65719..66117 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  DP112_RS00390 (DP112_00390) - 66217..66483 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  DP112_RS00395 (DP112_00395) ruvX 66483..66902 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  DP112_RS00400 (DP112_00400) - 66914..67234 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  DP112_RS11065 - 67519..67677 (+) 159 WP_164503888.1 hypothetical protein -
  DP112_RS00405 (DP112_00405) - 67707..68660 (-) 954 WP_114866097.1 IS30-like element ISSpn8 family transposase -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 43034.08 Da        Isoelectric Point: 4.4112

>NTDB_id=299460 DP112_RS00375 WP_114866096.1 63099..64280(+) (cinA) [Streptococcus suis strain HA1003]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEVARQRSDLVILCGGLGPTEDDLTKQT
LATFLGRKLVFDEKAIAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKMVASCLIEKKQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGWLSEEV
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=299460 DP112_RS00375 WP_114866096.1 63099..64280(+) (cinA) [Streptococcus suis strain HA1003]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGCCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTCCACACAGCTGTTGGAGATAATGAACAGCGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACTTGGTCATTCTCTGTGGAGGACTTGGTCCAACTGAGGATGACTTGACCAAGCAGACC
CTGGCGACCTTCTTAGGTAGAAAATTGGTCTTTGATGAAAAGGCTATAGCAAAATTAGACCGCTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGCCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTGCCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGTATTGG
TGAAAGCCAGCTGGTGACTGTTTTGGCGGACTTGATTGACAAGCAGACAGACCCAACTCTTGCACCCTATGCTAAGGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAATGGTAGCGTCTTG
TTTGATAGAGAAAAAACAAACTATAGCCATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGTCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGGAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCTGGCTATCAGAGGAAGTT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGCCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

94.402

100

0.944
  cinA Streptococcus mutans UA159

56.934

100

0.595
  cinA Streptococcus pneumoniae R6

56.01

100

0.593
  cinA Streptococcus mitis SK321

56.01

100

0.593
  cinA Streptococcus pneumoniae TIGR4

56.01

100

0.593
  cinA Streptococcus pneumoniae Rx1

56.01

100

0.593
  cinA Streptococcus mitis NCTC 12261

55.769

100

0.59
  cinA Streptococcus pneumoniae D39

55.769

100

0.59
  cinA Bacillus subtilis subsp. subtilis str. 168

40.921

99.491

0.407

Multiple sequence alignment