Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DK875_RS00315 Genome accession   NZ_CP030020
Coordinates   60551..61732 (+) Length   393 a.a.
NCBI ID   WP_004194467.1    Uniprot ID   -
Organism   Streptococcus suis strain ISU2514     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 55551..66732
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK875_RS00295 (DK875_00300) - 55634..56923 (-) 1290 WP_002935134.1 IS4-like element ISSsu2 family transposase -
  DK875_RS00300 (DK875_00305) mutL 57125..59062 (+) 1938 WP_004194473.1 DNA mismatch repair endonuclease MutL -
  DK875_RS00305 (DK875_00310) ruvA 59101..59691 (+) 591 WP_004194470.1 Holliday junction branch migration protein RuvA -
  DK875_RS00310 (DK875_00315) - 59945..60514 (+) 570 WP_004194469.1 DNA-3-methyladenine glycosylase I -
  DK875_RS00315 (DK875_00320) cinA 60551..61732 (+) 1182 WP_004194467.1 competence/damage-inducible protein A Machinery gene
  DK875_RS00320 (DK875_00325) recA 61784..62935 (+) 1152 WP_011922545.1 recombinase RecA Machinery gene
  DK875_RS00325 (DK875_00330) spx 63171..63569 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  DK875_RS00330 (DK875_00335) - 63669..63935 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -
  DK875_RS00335 (DK875_00340) ruvX 63935..64354 (+) 420 WP_002939356.1 Holliday junction resolvase RuvX -
  DK875_RS00340 (DK875_00345) - 64366..64686 (+) 321 WP_002939343.1 DUF1292 domain-containing protein -
  DK875_RS00345 (DK875_00350) - 64944..65522 (+) 579 WP_044667815.1 nucleotidyltransferase family protein -
  DK875_RS00350 (DK875_00355) comX/sigX 65595..65861 (+) 267 WP_002939335.1 hypothetical protein Regulator
  DK875_RS00355 (DK875_00360) rpsJ 66183..66491 (+) 309 WP_002939332.1 30S ribosomal protein S10 -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 43013.95 Da        Isoelectric Point: 4.4112

>NTDB_id=298346 DK875_RS00315 WP_004194467.1 60551..61732(+) (cinA) [Streptococcus suis strain ISU2514]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEVARQRSDLVILCGGLGPTEDDLTKQI
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRILRFFGIGESQLVTVLADLIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEEE
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVIGQLGTESGRLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATTSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=298346 DK875_RS00315 WP_004194467.1 60551..61732(+) (cinA) [Streptococcus suis strain ISU2514]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCGTTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTCTATTTCCACACAGCTGTTGGAGATAATGAACAGAGGCTTCTGTCTGTACTGG
AAGTAGCCCGTCAGCGGAGCGACCTGGTCATTCTCTGTGGAGGATTGGGTCCAACTGAGGATGACTTGACCAAGCAGATC
CTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTATCCTACGTTTTTTTGGCATTGG
TGAAAGCCAGTTGGTGACTGTTTTGGCGGACTTGATCGACAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAGGCAAATCTACGTTTGAATCAGTTGGAAGAAGAA
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTAAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCATCGGTCAGCTAGGGACAGAATCGGGCAGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTGGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATATCTCACTTTGGCTACGACCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

95.929

100

0.959
  cinA Streptococcus mutans UA159

56.691

100

0.593
  cinA Streptococcus pneumoniae R6

55.769

100

0.59
  cinA Streptococcus mitis SK321

55.769

100

0.59
  cinA Streptococcus pneumoniae TIGR4

55.769

100

0.59
  cinA Streptococcus pneumoniae Rx1

55.769

100

0.59
  cinA Streptococcus mitis NCTC 12261

55.529

100

0.588
  cinA Streptococcus pneumoniae D39

55.529

100

0.588
  cinA Bacillus subtilis subsp. subtilis str. 168

40.665

99.491

0.405

Multiple sequence alignment