Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DF184_RS03540 Genome accession   NZ_CP029398
Coordinates   696013..696675 (+) Length   220 a.a.
NCBI ID   WP_052501755.1    Uniprot ID   A0A0Z8P7Z1
Organism   Streptococcus suis strain HN105     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 691013..701675
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS03520 (DF184_03520) - 691580..692509 (-) 930 WP_044674354.1 ABC transporter substrate-binding protein -
  DF184_RS03525 (DF184_03525) - 692522..693307 (-) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  DF184_RS03530 (DF184_03530) - 693607..695052 (-) 1446 WP_109371312.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  DF184_RS03535 (DF184_03535) - 695198..695944 (+) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DF184_RS03540 (DF184_03540) comEA/celA/cilE 696013..696675 (+) 663 WP_052501755.1 helix-hairpin-helix domain-containing protein Machinery gene
  DF184_RS03545 (DF184_03545) comEC/celB 696659..698896 (+) 2238 WP_044674359.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DF184_RS03550 (DF184_03550) holA 698992..700023 (+) 1032 WP_109371314.1 DNA polymerase III subunit delta -
  DF184_RS03555 (DF184_03555) sodA 700136..700741 (+) 606 WP_105120723.1 superoxide dismutase SodA -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23466.21 Da        Isoelectric Point: 4.1234

>NTDB_id=292269 DF184_RS03540 WP_052501755.1 696013..696675(+) (comEA/celA/cilE) [Streptococcus suis strain HN105]
MDTIKTYIEMFKEYKWQISLPAVAGLLMATLLIFSQPAKSDQTGLTDFPQTEQTSSSSDLVEETSTEVSKEPSLLVVDVK
GAVVKPGLYTLEADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVGSKDENISVVANTTTSSAMSQEEKNTSLVN
LNTATEADLQTISGIGAKRATDIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=292269 DF184_RS03540 WP_052501755.1 696013..696675(+) (comEA/celA/cilE) [Streptococcus suis strain HN105]
ATGGATACGATTAAAACTTATATAGAAATGTTTAAAGAATACAAGTGGCAAATTTCCCTGCCAGCAGTGGCTGGCTTGCT
AATGGCGACGTTATTAATATTCAGCCAACCAGCTAAGTCTGATCAGACAGGCCTGACAGATTTTCCGCAGACCGAACAAA
CTTCTAGCAGCTCTGACTTGGTCGAGGAAACCAGTACAGAAGTAAGTAAGGAGCCCAGCCTGCTGGTCGTTGATGTCAAA
GGAGCGGTAGTAAAACCAGGACTCTACACTTTAGAAGCTGATGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCTAAGTCTATCAATCTGGCTCAAAAGCTCAGCGACGAAGCGGTGGTCTATGTGGGCAGCAAGG
ATGAAAACATCTCTGTAGTGGCCAATACGACTACCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTCAATACGGCGACCGAGGCTGACTTGCAGACCATTTCTGGTATTGGTGCCAAGCGAGCGACGGACATTATCGCCTATCG
TGAGGCCAACGGTGGATTCAAGTCGGTGGACGATCTCAACAATGTTTCGGGCATTGGCGACAAGACTATGGAAAGCATTC
GACCTTATGTTACGGTCGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-129)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8P7Z1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.982

100

0.486
  comEA/celA/cilE Streptococcus pneumoniae D39

47.982

100

0.486
  comEA/celA/cilE Streptococcus pneumoniae R6

47.982

100

0.486
  comEA/celA/cilE Streptococcus mitis NCTC 12261

47.982

100

0.486
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.402

99.545

0.482
  comEA/celA/cilE Streptococcus mitis SK321

46.847

100

0.473
  comEA Streptococcus thermophilus LMD-9

60.131

69.545

0.418
  comEA Lactococcus lactis subsp. cremoris KW2

39.631

98.636

0.391

Multiple sequence alignment