Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   DF184_RS03545 Genome accession   NZ_CP029398
Coordinates   696659..698896 (+) Length   745 a.a.
NCBI ID   WP_044674359.1    Uniprot ID   A0A0Z8JDK0
Organism   Streptococcus suis strain HN105     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 691659..703896
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DF184_RS03525 (DF184_03525) - 692522..693307 (-) 786 WP_014636900.1 ABC transporter ATP-binding protein -
  DF184_RS03530 (DF184_03530) - 693607..695052 (-) 1446 WP_109371312.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  DF184_RS03535 (DF184_03535) - 695198..695944 (+) 747 WP_014735985.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  DF184_RS03540 (DF184_03540) comEA/celA/cilE 696013..696675 (+) 663 WP_052501755.1 helix-hairpin-helix domain-containing protein Machinery gene
  DF184_RS03545 (DF184_03545) comEC/celB 696659..698896 (+) 2238 WP_044674359.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DF184_RS03550 (DF184_03550) holA 698992..700023 (+) 1032 WP_109371314.1 DNA polymerase III subunit delta -
  DF184_RS03555 (DF184_03555) sodA 700136..700741 (+) 606 WP_105120723.1 superoxide dismutase SodA -
  DF184_RS03560 (DF184_03560) - 701005..703029 (+) 2025 WP_109371316.1 bifunctional metallophosphatase/5'-nucleotidase -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 84019.97 Da        Isoelectric Point: 6.9059

>NTDB_id=292270 DF184_RS03545 WP_044674359.1 696659..698896(+) (comEC/celB) [Streptococcus suis strain HN105]
MLRSIKLPCQPIHLALLAVAAYFVVHSFSLLTMGLFSLVLTIFCVRQGKTVFLKTLPLLALCGLFFGYQKVQWERADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQIFYKLTSQEEQAYFQKLADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKLTAIKKIVPVQSWNIFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSLVYAGLTGFSVSVVRSLIQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYALLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPLIKITWVNGFFVFMEKIIVWVADLGLRPWILGKPSELVLLLLLVSLFLLYDFHRKKNWLLGLSLILALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSSQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDALEVAKQVKIGRIVVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIATYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALISAGENNRYKHPHQETLDRFDSRNIQ
VYRTDQQGAIRFRGWREWRIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=292270 DF184_RS03545 WP_044674359.1 696659..698896(+) (comEC/celB) [Streptococcus suis strain HN105]
ATGTTACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCACTC
TTTTTCCCTCTTGACAATGGGCCTGTTCAGTTTGGTGTTAACTATCTTTTGTGTCCGGCAAGGTAAGACGGTTTTCCTCA
AAACGCTGCCGCTTCTAGCCCTGTGCGGTCTGTTTTTCGGCTACCAAAAGGTCCAATGGGAGCGGGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTTCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGTCTGTCCTTTCGTGGTCGGGC
TGACGGACAAACCTATCAGATTTTCTATAAATTAACCAGTCAGGAGGAGCAGGCTTATTTTCAAAAGCTGGCAGACTTAG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGAGGAATTTCAAGGGTTTTGATTATCAGGCCTATCTG
AAAACCCAGGGCATATATCGGACAGTCAAGTTAACGGCGATTAAGAAGATTGTTCCAGTCCAGTCATGGAATATTTTTGA
CTGGCTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATGTCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTGTTGCGTCTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCCCTTGTTTATGCTGGTTTGACAGGCTTTTCGGTGTCGGTGGTGCGGTCACTTA
TCCAAAAAATTCTGGGCAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACAGTCTTTGTCTGTTTGCTGATTCTG
CCCCGATTTCTTTTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTCTTTTGCTGACGGTTTTTGATTTTGAAGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTTGGAATTTTGCCGGTGCTTATGACCTATTTCTTTG
CCTTCCAGCCCCTGTCTATTCTCTTGACCTTTGTATTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGCTTGTCGGTC
ATTTTTCTCCTCTCACCCTTGATCAAGATTACTTGGGTCAACGGATTTTTCGTTTTTATGGAGAAAATCATTGTCTGGGT
GGCGGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGAGCTGGTCCTCTTGCTTTTGCTGGTCAGCCTTTTCT
TGCTCTACGATTTCCACAGGAAGAAAAACTGGCTCCTGGGACTGAGCCTGATCCTCGCTCTGCTATTTTTCATAACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATTGGGCAGGGGGACAGTATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCTTGATTGATGTGGGCGGTCGGGTCGATTTTGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTTCGCAGGCAAATGCAG
AGCGGACCTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTCCTGACCCATACCGATACGGAC
CATGTGGGTGATGCGCTGGAAGTGGCTAAGCAGGTGAAAATTGGACGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATCAATGTGCCTGTCCATGTGGTAAAAGTGGGCGATCGCTTGCCAATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGCAACCTATCCCAACCTGCCAGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGATATCTGCAGGAGAAAATAACCGCTACAAGCATCCTCATCAAGAAACCTTGGACCGCTTTGACAGTCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAGGGAGTGGAGGATTGAAACGGTGAGGGAGTAA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(215-460)

Domain of unknown function (DUF4131) (DUF4131)

(30-175)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8JDK0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

54.189

99.329

0.538
  comEC/celB Streptococcus mitis NCTC 12261

52.949

100

0.53
  comEC/celB Streptococcus pneumoniae TIGR4

52.075

100

0.522
  comEC/celB Streptococcus pneumoniae Rx1

51.807

100

0.519
  comEC/celB Streptococcus pneumoniae D39

51.807

100

0.519
  comEC/celB Streptococcus pneumoniae R6

51.807

100

0.519
  comEC Lactococcus lactis subsp. cremoris KW2

49.132

100

0.494

Multiple sequence alignment