Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   DG474_RS08380 Genome accession   NZ_CP029257
Coordinates   1753501..1754757 (-) Length   418 a.a.
NCBI ID   WP_255778074.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1748501..1759757
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS08355 (DG474_08495) - 1748954..1749670 (-) 717 WP_044021424.1 YebC/PmpR family DNA-binding transcriptional regulator -
  DG474_RS08360 (DG474_08500) - 1749767..1751137 (-) 1371 WP_255778071.1 MATE family efflux transporter -
  DG474_RS08365 (DG474_08505) - 1751247..1751801 (+) 555 WP_070656881.1 GNAT family N-acetyltransferase -
  DG474_RS08370 (DG474_08510) - 1751931..1752125 (-) 195 WP_255778072.1 PspC domain-containing protein -
  DG474_RS08375 (DG474_08515) recA 1752295..1753446 (-) 1152 WP_255778073.1 recombinase RecA Machinery gene
  DG474_RS08380 (DG474_08520) cinA 1753501..1754757 (-) 1257 WP_255778074.1 competence/damage-inducible protein A Machinery gene
  DG474_RS08385 (DG474_08525) - 1754830..1755870 (-) 1041 WP_000592174.1 LCP family protein -
  DG474_RS08390 (DG474_08530) - 1755875..1756396 (-) 522 WP_084883435.1 GNAT family N-acetyltransferase -
  DG474_RS08395 (DG474_08535) tsaE 1756386..1756829 (-) 444 WP_255778075.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  DG474_RS08400 (DG474_08540) comM 1756913..1757536 (-) 624 WP_255778076.1 hypothetical protein Regulator
  DG474_RS08405 (DG474_08545) ndk 1757671..1758090 (-) 420 WP_000438280.1 nucleoside-diphosphate kinase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45300.69 Da        Isoelectric Point: 4.7265

>NTDB_id=291439 DG474_RS08380 WP_255778074.1 1753501..1754757(-) (cinA) [Streptococcus oralis strain CCUG 53468]
MKAEIIAVGTEILTGQIVNTNSQFLSEKLAEIGVDVYFQTAVGDNEARLLSLLEIASQRSNLVILTGGLGPTEDDLTKQT
LAKFLGKDLVFDPQAQEKLDIFFAHRPDYARTPNNERQAQIVEGATPLPNETGLAVGGVSEVDGVTYVVLPGPPSELKPM
VLNQLLPMLMTGTKLYSRVLRFFGIGESQLVTILADLIDHQTDPTLAPYAKTGEVTLRLSTKAVSQEKADQALDILENQI
LSRQTFEGISLRDICYGYGEETSLASVVVEELKKRQKSITAAESLTAGLFQATLADFSGVSAIFNGGFVTYSLEEKSKML
DIFEQELKEHGVVSEFTARKMAEQARIKTQSDYGVSLTGVAGPDSLEGHPAGTVFIGLAHEKGIEVIKANIAGRSRADVR
QIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=291439 DG474_RS08380 WP_255778074.1 1753501..1754757(-) (cinA) [Streptococcus oralis strain CCUG 53468]
ATGAAAGCAGAAATTATTGCTGTTGGAACAGAAATTTTAACAGGGCAGATTGTTAATACCAATTCTCAGTTTTTATCAGA
GAAACTAGCTGAAATCGGGGTAGATGTCTACTTCCAAACAGCTGTTGGAGATAATGAAGCTCGTCTTTTGTCCTTGCTGG
AGATTGCGAGTCAACGTAGTAATCTTGTGATTTTGACAGGGGGCTTGGGACCAACTGAGGATGATTTGACCAAACAAACT
CTGGCTAAATTTTTAGGAAAAGATCTAGTGTTTGACCCTCAAGCACAAGAGAAACTGGATATTTTCTTTGCTCATAGACC
TGACTATGCTCGGACACCGAATAATGAGCGCCAAGCCCAAATTGTAGAAGGGGCGACTCCACTGCCAAATGAGACAGGTT
TAGCAGTAGGAGGGGTTTCGGAAGTGGATGGAGTGACCTACGTGGTCCTTCCAGGACCGCCAAGTGAGTTGAAACCCATG
GTCTTAAATCAACTCTTGCCCATGCTGATGACAGGAACCAAACTGTACTCACGAGTGCTCCGTTTCTTTGGAATTGGGGA
GAGTCAGTTGGTAACCATTTTGGCGGATTTGATTGACCATCAAACCGATCCGACTTTGGCGCCGTATGCCAAGACGGGAG
AAGTGACCTTGCGTTTGTCTACAAAAGCAGTCAGTCAAGAAAAGGCTGATCAAGCACTGGACATCCTAGAAAATCAAATC
TTGAGTCGCCAAACTTTCGAGGGAATTTCTTTACGAGACATCTGTTATGGATATGGGGAAGAAACCAGCCTCGCAAGTGT
CGTTGTAGAAGAGCTAAAGAAGAGACAGAAAAGCATTACTGCGGCAGAAAGCTTGACGGCAGGTCTCTTTCAAGCGACAT
TAGCAGACTTTTCGGGCGTTTCAGCAATCTTTAATGGCGGTTTTGTCACTTACAGCCTAGAAGAAAAGTCCAAGATGTTG
GATATTTTCGAGCAAGAACTAAAAGAACACGGGGTTGTTTCAGAGTTTACGGCTCGAAAAATGGCAGAGCAGGCACGGAT
CAAGACTCAGTCTGATTATGGAGTCAGTCTGACAGGTGTAGCTGGGCCAGATAGCCTAGAGGGGCATCCGGCTGGTACAG
TTTTTATTGGACTGGCACATGAAAAAGGGATAGAGGTGATCAAGGCTAATATCGCAGGACGGAGTCGAGCAGATGTTCGA
CAGATTGCGGTCATGCATGCTTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-243)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

89.474

100

0.895
  cinA Streptococcus mitis NCTC 12261

88.756

100

0.888
  cinA Streptococcus pneumoniae TIGR4

88.756

100

0.888
  cinA Streptococcus pneumoniae Rx1

88.756

100

0.888
  cinA Streptococcus pneumoniae R6

88.756

100

0.888
  cinA Streptococcus pneumoniae D39

88.517

100

0.885
  cinA Streptococcus mutans UA159

70.574

100

0.706
  cinA Streptococcus suis isolate S10

55.288

99.522

0.55
  cinA Bacillus subtilis subsp. subtilis str. 168

44.976

100

0.45

Multiple sequence alignment