Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   SGO_RS07850 Genome accession   NC_009785
Coordinates   1657744..1658409 (-) Length   221 a.a.
NCBI ID   WP_012130666.1    Uniprot ID   A8AYM0
Organism   Streptococcus gordonii str. Challis substr. CH1     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1652744..1663409
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SGO_RS07835 (SGO_1599) - 1653714..1654319 (-) 606 WP_012130663.1 superoxide dismutase -
  SGO_RS07840 (SGO_1600) holA 1654392..1655429 (-) 1038 WP_012130664.1 DNA polymerase III subunit delta -
  SGO_RS07845 (SGO_1601) comEC/celB 1655520..1657760 (-) 2241 WP_012130665.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  SGO_RS07850 (SGO_1602) comEA/celA/cilE 1657744..1658409 (-) 666 WP_012130666.1 helix-hairpin-helix domain-containing protein Machinery gene
  SGO_RS07855 (SGO_1603) - 1658506..1659033 (-) 528 WP_012130667.1 HXXEE domain-containing protein -
  SGO_RS07860 (SGO_1604) - 1659072..1659812 (-) 741 WP_041789898.1 lysophospholipid acyltransferase family protein -
  SGO_RS07865 (SGO_1605) - 1659942..1662311 (+) 2370 WP_012130669.1 cation-translocating P-type ATPase -
  SGO_RS07870 (SGO_1606) - 1662416..1663162 (+) 747 WP_041789750.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23562.26 Da        Isoelectric Point: 4.8121

>NTDB_id=29082 SGO_RS07850 WP_012130666.1 1657744..1658409(-) (comEA/celA/cilE) [Streptococcus gordonii str. Challis substr. CH1]
MIENLIEKAKQYKIALGLSLLGAIAASFILLQGRDQGGTDVQQLTEQTSSSSSYMNEKSNKSNEISQSETEDQLVTVDVK
GAVKKPGVYQLQSNSRVHDALEKAGGLTDEADLKSINQAQKLSDEAVVYVAKVGENAVDVTTSAPTSATSGTGQTKSALV
NLNTATEADFQTISGIGQKRAQDIIAYREANGRFKSVDDLKNVSGIGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 666 bp        

>NTDB_id=29082 SGO_RS07850 WP_012130666.1 1657744..1658409(-) (comEA/celA/cilE) [Streptococcus gordonii str. Challis substr. CH1]
ATGATAGAAAATTTGATAGAAAAAGCAAAGCAATATAAAATTGCTCTAGGTCTCAGTCTATTAGGAGCGATTGCAGCAAG
CTTTATTTTACTACAGGGAAGAGACCAAGGGGGGACAGATGTTCAGCAATTGACAGAGCAAACTTCTTCCTCTAGTTCAT
ATATGAATGAAAAAAGTAACAAGAGCAACGAGATCAGTCAATCCGAGACAGAAGATCAGTTGGTTACAGTTGATGTCAAG
GGGGCGGTAAAAAAGCCTGGTGTCTATCAGTTGCAGTCTAATAGTCGGGTTCATGATGCTTTAGAAAAGGCTGGTGGTTT
AACTGACGAAGCTGACTTAAAATCCATCAATCAGGCTCAGAAACTAAGTGATGAGGCAGTAGTATATGTGGCCAAGGTCG
GAGAAAATGCTGTAGATGTTACAACGAGTGCTCCTACAAGTGCAACATCAGGCACCGGTCAGACAAAATCAGCACTTGTC
AATCTTAATACAGCAACAGAAGCAGACTTTCAAACTATTTCTGGTATCGGCCAAAAACGAGCACAGGATATTATTGCTTA
TCGAGAAGCCAATGGTAGGTTTAAGTCTGTAGATGATCTGAAAAATGTATCAGGTATTGGGGCCAAAACTCTAGAAAAAT
TAAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(158-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8AYM0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis SK321

48.869

100

0.489
  comEA/celA/cilE Streptococcus mitis NCTC 12261

49.091

99.548

0.489
  comEA/celA/cilE Streptococcus pneumoniae D39

48.636

99.548

0.484
  comEA/celA/cilE Streptococcus pneumoniae R6

48.636

99.548

0.484
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

48.636

99.548

0.484
  comEA/celA/cilE Streptococcus pneumoniae Rx1

48.636

99.548

0.484
  comEA Streptococcus thermophilus LMD-9

56.757

66.968

0.38
  comEA Latilactobacillus sakei subsp. sakei 23K

35

100

0.38
  comEA Bacillus subtilis subsp. subtilis str. 168

38.863

95.475

0.371

Multiple sequence alignment