Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   ECS88_RS22050 Genome accession   NC_011742
Coordinates   4063679..4064269 (-) Length   196 a.a.
NCBI ID   WP_001332271.1    Uniprot ID   A0A0H2Z4C4
Organism   Escherichia coli S88     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4058679..4069269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ECS88_RS22035 (ECS88_4091) uhpT 4059319..4060710 (-) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -
  ECS88_RS22040 (ECS88_4092) uhpC 4060848..4062167 (-) 1320 WP_001514377.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  ECS88_RS22045 (ECS88_4093) uhpB 4062177..4063679 (-) 1503 WP_001332272.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  ECS88_RS22050 (ECS88_4094) letA 4063679..4064269 (-) 591 WP_001332271.1 transcriptional regulator UhpA Regulator
  ECS88_RS22055 (ECS88_4095) ilvN 4064342..4064632 (-) 291 WP_001181706.1 acetolactate synthase small subunit -
  ECS88_RS22060 (ECS88_4096) ilvB 4064636..4066324 (-) 1689 WP_000168473.1 acetolactate synthase large subunit -
  ECS88_RS22065 (ECS88_5092) ivbL 4066430..4066528 (-) 99 WP_001312198.1 ilvB operon leader peptide IvbL -
  ECS88_RS27860 ysdE 4066773..4066847 (-) 75 WP_211180519.1 protein YsdE -
  ECS88_RS22075 (ECS88_4098) emrD 4066929..4068113 (+) 1185 WP_001332269.1 multidrug efflux MFS transporter EmrD -
  ECS88_RS22080 (ECS88_4099) yidF 4068121..4068618 (-) 498 WP_000148034.1 radical SAM protein -
  ECS88_RS22085 (ECS88_4100) yidG 4068615..4068977 (-) 363 WP_001113443.1 DUF202 domain-containing protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20836.26 Da        Isoelectric Point: 5.6059

>NTDB_id=29081 ECS88_RS22050 WP_001332271.1 4063679..4064269(-) (letA) [Escherichia coli S88]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGCGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=29081 ECS88_RS22050 WP_001332271.1 4063679..4064269(-) (letA) [Escherichia coli S88]
ATGATCACCGTTGCCCTTATAGACGATCACCTTATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGTGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCTGATATCTCCGGTCTGGAGCTTCTAAGCCAGCTGCCGAAAGGCATGGCGACAATTATGCTCTCCGTT
CACGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCCGGGGCGCGCGGCTTTCTCTCCAAACGCTGTAGCCCGGATGA
ACTCATTGCTGCGGTGCATACGGTTGCCACTGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GCCAGGACCCGCTAACCAAACGCGAACGCCAGGTGGCAGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCCGCC
GAACTGGGCTTGTCGCCGAAAACGGTACACGTCCATCGCGCCAATCTGATGGAAAAACTGGGCGTCAGTAACGACGTTGA
ACTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(136-191)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2Z4C4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378

Multiple sequence alignment