Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C7U63_RS18080 Genome accession   NZ_CP028133
Coordinates   3857241..3858482 (-) Length   413 a.a.
NCBI ID   WP_005355091.1    Uniprot ID   A0A2T4MY12
Organism   Aeromonas veronii strain 17ISAe     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3852241..3863482
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C7U63_RS18055 (C7U63_18040) mutT 3854233..3854637 (+) 405 WP_107684321.1 8-oxo-dGTP diphosphatase MutT -
  C7U63_RS18060 (C7U63_18045) yacG 3854715..3854909 (-) 195 WP_107684320.1 DNA gyrase inhibitor YacG -
  C7U63_RS18065 (C7U63_18050) zapD 3854919..3855641 (-) 723 WP_005336141.1 cell division protein ZapD -
  C7U63_RS18070 (C7U63_18055) coaE 3855679..3856293 (-) 615 WP_107684319.1 dephospho-CoA kinase -
  C7U63_RS18075 (C7U63_18060) pilD 3856307..3857179 (-) 873 WP_107684318.1 prepilin peptidase Machinery gene
  C7U63_RS18080 (C7U63_18065) pilC 3857241..3858482 (-) 1242 WP_005355091.1 type II secretion system F family protein Machinery gene
  C7U63_RS18085 (C7U63_18070) pilB 3858722..3860428 (-) 1707 WP_005336134.1 PilB family type IVa pilus assembly ATPase TapB Machinery gene
  C7U63_RS18090 (C7U63_18075) - 3860432..3860908 (-) 477 WP_371733114.1 pilin -
  C7U63_RS18100 (C7U63_18085) nadC 3861226..3862089 (-) 864 WP_043821973.1 carboxylating nicotinate-nucleotide diphosphorylase -
  C7U63_RS18105 (C7U63_18090) - 3862093..3862563 (-) 471 WP_107684317.1 retropepsin-like aspartic protease family protein -
  C7U63_RS18110 (C7U63_18095) ampD 3862694..3863269 (+) 576 WP_107684316.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 413 a.a.        Molecular weight: 45441.57 Da        Isoelectric Point: 9.7221

>NTDB_id=281486 C7U63_RS18080 WP_005355091.1 3857241..3858482(-) (pilC) [Aeromonas veronii strain 17ISAe]
MATLTKKNNAPKKVFAFRWHGVNRKGQKVSGELQADSINTVKTELRKQGVNVTKVAKKSQGLFSKGGAKIKPMDIAIVSR
QITTMLSAGVPLVQSLQIIARSHEKASMRELMGQIAADVETGTPMSEALRRHPLYFDDLYCDLVEAGEQSGALETIYDRI
ATYREKSEALKSKIKKAMFYPTMVILVAIVVTSILLLFVIPQFEDIFKSFGAELPVFTQFVIGISRFMQNWWYVFFGGTA
LGIFLYVRAWRASQKVKDNTDKFVLTIPVVGMILHKAAMARFARTLSTTFSAGIPLVDALISAAGASGNYVYRTAVMAIR
NEVVAGMQINVAMRTVDLFPDMVIQMVMIGEESGAIDDMLSKVATIFEQEVDDLVDGLTSLLEPLIMVVLGVLVGGMVIA
MYLPIFKLGEVVG

Nucleotide


Download         Length: 1242 bp        

>NTDB_id=281486 C7U63_RS18080 WP_005355091.1 3857241..3858482(-) (pilC) [Aeromonas veronii strain 17ISAe]
ATGGCAACCCTAACGAAAAAGAACAATGCCCCCAAGAAAGTCTTCGCCTTCCGCTGGCACGGGGTAAACCGCAAGGGGCA
GAAGGTCTCCGGCGAGCTGCAGGCCGATAGCATCAACACCGTCAAGACAGAACTGCGCAAGCAGGGGGTCAACGTCACCA
AGGTGGCCAAGAAATCCCAGGGGCTCTTCTCCAAGGGCGGCGCCAAGATCAAACCGATGGATATCGCCATCGTCTCACGC
CAGATCACCACCATGCTCTCCGCCGGCGTACCACTGGTGCAGAGCCTGCAGATCATCGCCCGCAGCCACGAGAAAGCCTC
GATGCGAGAGCTGATGGGGCAGATTGCCGCCGATGTGGAGACTGGTACCCCCATGTCGGAGGCGCTGCGTCGCCATCCCC
TCTACTTTGATGATCTCTATTGCGATCTGGTGGAGGCCGGTGAGCAATCCGGTGCACTGGAGACCATCTACGACCGTATC
GCCACCTATCGGGAAAAGTCGGAAGCGCTCAAGTCGAAGATCAAGAAGGCGATGTTCTACCCCACCATGGTCATTCTGGT
CGCTATCGTGGTGACCTCCATCCTGCTGCTGTTCGTCATTCCGCAGTTCGAGGATATCTTCAAGAGCTTCGGCGCCGAGC
TACCGGTGTTCACCCAGTTTGTTATCGGCATCTCCCGCTTTATGCAGAACTGGTGGTATGTCTTCTTTGGTGGCACGGCC
CTTGGCATCTTCCTTTATGTGCGGGCCTGGCGGGCCTCCCAGAAGGTGAAAGACAATACCGACAAGTTCGTCCTCACCAT
TCCGGTGGTCGGGATGATCCTGCACAAGGCGGCGATGGCCCGCTTTGCCCGCACCCTGTCGACCACCTTCTCCGCCGGTA
TTCCGCTGGTAGATGCGCTGATTTCGGCGGCTGGCGCCTCCGGCAACTATGTCTATCGCACCGCGGTAATGGCCATCCGC
AACGAGGTGGTGGCCGGTATGCAGATCAACGTGGCGATGCGCACCGTCGATCTCTTCCCCGACATGGTGATCCAGATGGT
GATGATCGGTGAGGAGTCCGGTGCCATCGATGATATGCTCTCCAAGGTCGCCACCATCTTCGAACAGGAGGTGGATGATC
TGGTCGATGGCCTCACCAGCCTGCTGGAACCCCTCATCATGGTGGTGCTCGGGGTGCTGGTCGGCGGCATGGTTATTGCC
ATGTACCTGCCCATCTTCAAGCTTGGCGAAGTGGTAGGCTGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(282-404)

Type II secretion system (T2SS), protein F (T2SSF)

(79-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2T4MY12

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

57.323

95.884

0.55
  pilC Acinetobacter baumannii D1279779

53.75

96.852

0.521
  pilC Acinetobacter baylyi ADP1

52.393

96.126

0.504
  pilC Legionella pneumophila strain ERS1305867

50.985

98.305

0.501
  pilC Vibrio cholerae strain A1552

46.883

97.094

0.455
  pilC Vibrio campbellii strain DS40M4

45.792

97.821

0.448
  pilG Neisseria gonorrhoeae MS11

40.247

98.063

0.395
  pilG Neisseria meningitidis 44/76-A

40

98.063

0.392
  pilC Thermus thermophilus HB27

38

96.852

0.368

Multiple sequence alignment