Detailed information NTG0281485

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: C7U63_RS18075
• Genome accession: NZ_CP028133
• Coordinates: 3856307..3857179 (-)
• Length: 290 a.a.
• NCBI ID: WP_107684318.1
• Uniprot ID: A0A2T4MXS2
• Organism: Aeromonas veronii strain 17ISAe
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3851307..3862179

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C7U63_RS18050 (C7U63_18035)	secA	3851328..3854048 (+)	2721	WP_107684322.1	preprotein translocase subunit SecA	-
C7U63_RS18055 (C7U63_18040)	mutT	3854233..3854637 (+)	405	WP_107684321.1	8-oxo-dGTP diphosphatase MutT	-
C7U63_RS18060 (C7U63_18045)	yacG	3854715..3854909 (-)	195	WP_107684320.1	DNA gyrase inhibitor YacG	-
C7U63_RS18065 (C7U63_18050)	zapD	3854919..3855641 (-)	723	WP_005336141.1	cell division protein ZapD	-
C7U63_RS18070 (C7U63_18055)	coaE	3855679..3856293 (-)	615	WP_107684319.1	dephospho-CoA kinase	-
C7U63_RS18075 (C7U63_18060)	pilD	3856307..3857179 (-)	873	WP_107684318.1	prepilin peptidase	Machinery gene
C7U63_RS18080 (C7U63_18065)	pilC	3857241..3858482 (-)	1242	WP_005355091.1	type II secretion system F family protein	Machinery gene
C7U63_RS18085 (C7U63_18070)	pilB	3858722..3860428 (-)	1707	WP_005336134.1	PilB family type IVa pilus assembly ATPase TapB	Machinery gene
C7U63_RS18090 (C7U63_18075)	-	3860432..3860908 (-)	477	WP_371733114.1	pilin	-
C7U63_RS18100 (C7U63_18085)	nadC	3861226..3862089 (-)	864	WP_043821973.1	carboxylating nicotinate-nucleotide diphosphorylase	-

Sequence

Protein

• Length: 290 a.a.
• Molecular weight: 32228.51 Da
• Isoelectric Point: 6.3694

>NTDB_id=281485 C7U63_RS18075 WP_107684318.1 3856307..3857179(-) (pilD) [Aeromonas veronii strain 17ISAe]
MTLLLELAHSLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFTPDEEATAPECYNLMVPRSACPHCGHA
ITALENIPLLSWIWLKGRCRDCQAPISARYPLVELLTALLSVAVAMVITPGWSTLAALLLTWVLVALTFIDLDKMLLPDQ
LTLPLLWGGLLFNLAGGFVPLADAVIGAMAGYLVLWSLYWAFKLLTDKEGMGYGDFKLLAALGAWLGWQALPIILLLSSL
IGAVIGISLIALHKHHQGKPIPFGPYLAIAGWIALLWGDTITRWYLSTLL

Nucleotide

• Length: 873 bp

>NTDB_id=281485 C7U63_RS18075 WP_107684318.1 3856307..3857179(-) (pilD) [Aeromonas veronii strain 17ISAe]
ATGACACTTCTTCTCGAGCTGGCTCACAGCTTGCCCTGGCTCTACTTCTCGCTGGTTTTTCTCTTCTCCCTGATGATCGG
CAGCTTCCTTAACGTGGTCATCCACCGCTTGCCCATCATGCTGGAACGGGAGTGGCAGGCCGAATATCGCAGCTACTTCA
CCCCTGATGAGGAGGCCACTGCGCCAGAGTGCTACAACCTGATGGTGCCGCGCTCCGCATGCCCTCACTGTGGCCACGCC
ATCACTGCGCTGGAGAACATCCCGCTGTTGAGCTGGATCTGGCTCAAAGGGCGTTGCCGCGACTGTCAGGCCCCCATCTC
GGCCCGCTATCCGCTGGTAGAGCTGCTGACCGCCCTGCTCTCGGTGGCCGTTGCCATGGTCATAACGCCAGGCTGGAGCA
CACTGGCCGCCCTGCTGCTGACCTGGGTGCTGGTCGCCCTCACCTTCATCGATCTCGACAAAATGTTGCTGCCCGACCAG
CTCACCCTGCCACTGCTGTGGGGCGGGCTGCTGTTCAATCTGGCTGGTGGCTTCGTGCCGCTGGCGGATGCCGTGATCGG
TGCCATGGCGGGCTATCTGGTGCTCTGGAGCCTCTACTGGGCCTTCAAGCTGCTCACTGACAAGGAGGGGATGGGCTATG
GCGACTTCAAGCTGCTGGCGGCGCTGGGCGCCTGGCTCGGTTGGCAGGCGCTGCCCATAATTCTGCTGCTCTCATCCCTG
ATCGGCGCAGTGATCGGCATCAGTCTGATCGCCTTGCACAAACACCATCAGGGCAAGCCCATCCCCTTCGGCCCCTACCT
CGCCATCGCGGGCTGGATCGCCCTGCTATGGGGCGATACCATCACCCGCTGGTATCTCTCTACCCTGCTTTGA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (139-247)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (21-126)

3D structure

• AlphaFold DB: A0A2T4MXS2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	59.441	98.621	0.586
pilD	Vibrio campbellii strain DS40M4	55.052	98.966	0.545
pilD	Acinetobacter nosocomialis M2	52.688	96.207	0.507
pilD	Acinetobacter baumannii D1279779	52.33	96.207	0.503
pilD	Neisseria gonorrhoeae MS11	50	93.103	0.466