Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   VEIS_RS18970 Genome accession   NC_008786
Coordinates   4308265..4309488 (+) Length   407 a.a.
NCBI ID   WP_011811614.1    Uniprot ID   A1WPS0
Organism   Verminephrobacter eiseniae EF01-2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 4303265..4314488
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VEIS_RS18940 (Veis_3915) obgE 4303348..4304439 (-) 1092 WP_011811609.1 GTPase ObgE -
  VEIS_RS18945 (Veis_3916) rpmA 4304508..4304783 (-) 276 WP_011811610.1 50S ribosomal protein L27 -
  VEIS_RS18950 (Veis_3917) rplU 4304802..4305113 (-) 312 WP_011811611.1 50S ribosomal protein L21 -
  VEIS_RS18955 (Veis_3918) - 4305310..4306239 (+) 930 WP_041951049.1 polyprenyl synthetase family protein -
  VEIS_RS18965 (Veis_3919) pilB 4306503..4308239 (+) 1737 WP_041950195.1 type IV-A pilus assembly ATPase PilB Machinery gene
  VEIS_RS18970 (Veis_3920) pilC 4308265..4309488 (+) 1224 WP_011811614.1 type II secretion system F family protein Machinery gene
  VEIS_RS18975 (Veis_3921) - 4309488..4310372 (+) 885 WP_011811615.1 A24 family peptidase -
  VEIS_RS18980 (Veis_3922) coaE 4310376..4311008 (+) 633 WP_011811616.1 dephospho-CoA kinase -
  VEIS_RS18985 (Veis_3923) zapD 4311052..4311807 (+) 756 WP_011811617.1 cell division protein ZapD -
  VEIS_RS18990 (Veis_3924) - 4311828..4312049 (+) 222 WP_011811618.1 DNA gyrase inhibitor YacG -
  VEIS_RS18995 (Veis_3925) - 4312083..4312550 (-) 468 WP_011811619.1 NUDIX domain-containing protein -
  VEIS_RS19000 (Veis_3926) - 4312528..4313400 (-) 873 WP_041950196.1 ATP-binding protein -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 44815.70 Da        Isoelectric Point: 9.2732

>NTDB_id=27319 VEIS_RS18970 WP_011811614.1 4308265..4309488(+) (pilC) [Verminephrobacter eiseniae EF01-2]
MATITAAKREIKEKVFEWEGKDRNGKIVRGEIRAVGENQVQASLRRQGVLSTKIKERRMRSGKKVKPKDIALFTRQLATM
MKAGVPLLQSFDIVGRGSTNPSVTKLLNDIRSDIETGTSLSGAFRHYPKYFNELYCNLVEAGETAGILESLLDRLATYME
KTEAIKSRIKSALMYPSAVLCVAFVVVSLIMVFVIPAFKEVFTSFGADLPPPTLLVMAISETFVHWWWLIFGGVGGGIFF
FMQSWRRNEKLQKFMDRLLLRLPIFGVLFEKACVARWTRTLSTMFAAGVPLVEALDSVGGAAGNSVYASVTDKIQQEVST
GTSLTVAMGNANIFPTMVLQMCAIGEETGSIDHMLGKAADFYEAEVDTMVAGISSLMEPIIIVFLGCLIGGIVISMYLPI
FKLGQVV

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=27319 VEIS_RS18970 WP_011811614.1 4308265..4309488(+) (pilC) [Verminephrobacter eiseniae EF01-2]
ATGGCAACCATCACGGCAGCAAAAAGAGAGATCAAGGAAAAAGTCTTCGAATGGGAAGGCAAGGACCGCAATGGAAAAAT
CGTCCGCGGCGAGATCCGGGCGGTTGGTGAAAACCAGGTGCAGGCGAGCCTGCGCCGTCAAGGGGTGCTCTCGACGAAAA
TCAAGGAGCGCCGCATGCGCTCCGGCAAGAAGGTCAAACCCAAGGATATTGCACTTTTTACCCGGCAATTGGCGACCATG
ATGAAGGCCGGTGTTCCGCTGCTGCAGTCCTTCGACATCGTGGGGCGTGGCTCTACCAACCCCAGTGTCACCAAATTGCT
CAATGACATCCGCTCCGATATCGAGACCGGCACTTCCCTGAGCGGTGCCTTCAGACATTATCCAAAATACTTCAACGAGC
TCTACTGCAATCTGGTGGAGGCCGGCGAAACCGCCGGTATTTTGGAATCCCTGCTGGATCGGCTTGCCACTTACATGGAA
AAAACCGAGGCGATCAAGTCACGGATCAAATCGGCCTTGATGTACCCCAGCGCGGTGCTGTGCGTGGCCTTTGTGGTGGT
GTCGCTGATCATGGTTTTCGTGATCCCGGCCTTCAAAGAGGTTTTCACCTCCTTCGGCGCCGATCTTCCGCCGCCCACCT
TGCTCGTCATGGCCATCAGTGAGACTTTCGTCCACTGGTGGTGGTTGATTTTCGGGGGTGTCGGTGGTGGCATTTTCTTC
TTCATGCAGTCCTGGCGGCGCAATGAGAAATTGCAGAAGTTCATGGATCGCCTGCTGTTGCGCTTGCCGATTTTCGGGGT
ACTGTTCGAGAAAGCATGCGTTGCGCGCTGGACCCGAACGCTGTCGACGATGTTTGCCGCCGGGGTTCCGCTCGTGGAGG
CGCTGGACTCGGTGGGGGGGGCCGCAGGCAACTCGGTCTACGCGTCGGTAACGGACAAGATTCAGCAGGAAGTCTCCACC
GGCACCAGTCTCACGGTGGCCATGGGCAACGCCAATATCTTTCCGACGATGGTGCTGCAAATGTGTGCCATTGGTGAAGA
GACCGGTTCCATCGATCACATGCTGGGCAAGGCCGCCGATTTTTACGAGGCAGAAGTCGATACCATGGTGGCGGGCATAT
CCAGCCTGATGGAGCCGATCATCATCGTTTTTCTTGGCTGCCTGATCGGCGGCATCGTCATCTCGATGTATCTGCCGATC
TTCAAATTGGGACAGGTCGTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(277-399)

Type II secretion system (T2SS), protein F (T2SSF)

(73-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1WPS0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Pseudomonas stutzeri DSM 10701

51.485

99.263

0.511
  pilG Neisseria gonorrhoeae MS11

50.63

97.543

0.494
  pilC Acinetobacter baylyi ADP1

48.894

100

0.489
  pilG Neisseria meningitidis 44/76-A

49.874

97.543

0.486
  pilC Legionella pneumophila strain ERS1305867

47.98

97.297

0.467
  pilC Acinetobacter baumannii D1279779

47.103

97.543

0.459
  pilC Vibrio cholerae strain A1552

38.631

100

0.388
  pilC Thermus thermophilus HB27

37.469

99.017

0.371
  pilC Vibrio campbellii strain DS40M4

37.065

98.771

0.366

Multiple sequence alignment