Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   C1S76_RS14240 Genome accession   NZ_CP025796
Coordinates   2959297..2960520 (-) Length   407 a.a.
NCBI ID   WP_009707569.1    Uniprot ID   A0A812FEE4
Organism   Vibrio owensii strain 051011B     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2954297..2965520
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C1S76_RS14205 rimM 2954538..2955086 (+) 549 WP_005438038.1 ribosome maturation factor RimM -
  C1S76_RS14210 trmD 2955114..2955857 (+) 744 WP_005425529.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  C1S76_RS14215 rplS 2955899..2956252 (+) 354 WP_005438036.1 50S ribosomal protein L19 -
  C1S76_RS14220 yacG 2956715..2956909 (-) 195 WP_009707573.1 DNA gyrase inhibitor YacG -
  C1S76_RS14225 zapD 2956972..2957712 (-) 741 WP_009707572.1 cell division protein ZapD -
  C1S76_RS14230 coaE 2957740..2958354 (-) 615 WP_045413058.1 dephospho-CoA kinase -
  C1S76_RS14235 pilD 2958355..2959224 (-) 870 WP_045413056.1 prepilin peptidase Machinery gene
  C1S76_RS14240 pilC 2959297..2960520 (-) 1224 WP_009707569.1 type II secretion system F family protein Machinery gene
  C1S76_RS14245 pilB 2960554..2962239 (-) 1686 WP_045413053.1 type IV-A pilus assembly ATPase PilB Machinery gene
  C1S76_RS14250 - 2962243..2962683 (-) 441 WP_045413051.1 type IV pilin protein -
  C1S76_RS14260 nadC 2962948..2963835 (-) 888 WP_039840279.1 carboxylating nicotinate-nucleotide diphosphorylase -
  C1S76_RS14265 ampD 2963928..2964479 (+) 552 WP_045413040.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 44910.22 Da        Isoelectric Point: 10.3176

>NTDB_id=263900 C1S76_RS14240 WP_009707569.1 2959297..2960520(-) (pilC) [Vibrio owensii strain 051011B]
MKTITPQLKNYRWKGINSSGKKTSGNVLAMTEIEVRERLDAQHIKIKKLKKGSISFITKLSHRVKGKDITVFTRQIATML
MTGVPIVQALKLVSENHKKAEMKSILMSVTRAVEAGTPMSKAMRTASTHFDPLYTDLIATGEQSGNLSQVFERLATYREK
SEQLRAKVIKALIYPAMVVLVALGVSYLMLTRVIPEFEKMFVGFGADLPAFTQMVLDLSAWTQNWGPFIGLGFLSLLIGS
KVISNRSDSFKLLLARSSLKIPILGPVLSKAAIAKFSRTLATSFSAGIPILTALKTTSKTSGNMHYQLAIEEVYRDTAAG
MPMYIAMRNCNVFPELVLQMVMIGEESGRLDDMLNKIAAIYEFEVDNTVDNLSKILEPLIIVFLGVVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=263900 C1S76_RS14240 WP_009707569.1 2959297..2960520(-) (pilC) [Vibrio owensii strain 051011B]
ATGAAAACCATTACTCCTCAACTTAAGAACTACCGTTGGAAAGGCATCAATAGCTCGGGCAAAAAGACCTCAGGTAATGT
CCTCGCCATGACGGAAATCGAAGTAAGAGAACGCCTCGATGCTCAGCACATCAAAATTAAGAAACTGAAAAAGGGCAGTA
TTTCTTTTATTACTAAATTGAGCCATAGAGTCAAAGGGAAAGACATCACGGTGTTTACTCGCCAAATTGCTACCATGCTA
ATGACGGGTGTACCAATCGTTCAAGCACTCAAATTGGTTTCAGAGAACCATAAAAAAGCGGAAATGAAATCGATTTTAAT
GAGTGTCACAAGGGCGGTAGAGGCCGGAACACCAATGTCGAAAGCCATGCGTACAGCTAGCACGCATTTCGACCCGCTTT
ATACCGATTTAATCGCAACGGGTGAGCAGTCTGGTAACTTATCCCAAGTCTTCGAGCGTTTGGCAACCTACAGAGAAAAA
AGCGAACAGTTGCGCGCGAAAGTGATCAAAGCACTTATTTATCCGGCCATGGTTGTCTTGGTTGCCTTAGGGGTTTCCTA
CCTAATGCTGACTCGGGTCATTCCTGAGTTTGAAAAGATGTTTGTAGGCTTTGGCGCAGATTTACCTGCGTTTACGCAAA
TGGTATTAGACCTCTCTGCTTGGACTCAAAACTGGGGCCCTTTCATTGGACTCGGTTTCTTGAGTCTCTTGATCGGCTCA
AAAGTCATATCGAACCGCTCTGATTCTTTCAAGCTATTGCTCGCTCGATCCAGTTTAAAGATTCCCATCTTGGGCCCTGT
TTTATCCAAAGCCGCCATTGCCAAGTTTAGCCGTACGCTTGCCACTAGTTTTAGTGCCGGTATCCCAATCCTCACCGCGT
TAAAAACCACCTCAAAGACCTCGGGTAACATGCACTATCAATTGGCAATAGAAGAGGTATACCGAGATACGGCTGCGGGT
ATGCCAATGTATATTGCTATGCGCAACTGCAATGTCTTCCCCGAACTAGTATTGCAAATGGTCATGATTGGCGAAGAATC
TGGCCGCTTAGATGACATGCTCAACAAGATTGCAGCAATTTACGAGTTTGAGGTCGACAATACCGTCGATAACCTAAGTA
AGATTCTTGAGCCGCTGATCATCGTTTTTCTCGGTGTCGTTGTTGGCGGTTTGGTCACAGCAATGTACTTGCCAATCTTT
AACTTGATGAGCGTATTGGGATAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A812FEE4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

95.577

100

0.956
  pilC Vibrio cholerae strain A1552

73.827

99.509

0.735
  pilC Acinetobacter baylyi ADP1

42.04

98.771

0.415
  pilG Neisseria meningitidis 44/76-A

40.098

100

0.403
  pilC Legionella pneumophila strain ERS1305867

40.295

100

0.403
  pilC Acinetobacter baumannii D1279779

40.75

98.28

0.4
  pilC Pseudomonas stutzeri DSM 10701

40.657

97.297

0.396
  pilG Neisseria gonorrhoeae MS11

39.851

99.263

0.396

Multiple sequence alignment